G:12286

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Official Symbol Cacna1a
Aliases la, tg, EA2, FHM, MHP, rkr, APCA, HPCA, MHP1, SCA6, Caca1a, Cav2.1, Ccha1a, leaner, nmf352, rocker, alpha1A, Cacnl1a4, tottering
EntrezGene 12286
UniProt Coming Soon
Unique Molecular Interactions 22
Total Molecular Interactions 32
Total Single Events 308
Unique Interaction Partners 16

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cacna1a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cacna1a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cacna1a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
4 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
5 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
6 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
7 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
8 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
9 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
10 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
11 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
12 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
13 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
14 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
15 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
16 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
17 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
18 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
19 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
20 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
21 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
22 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12286. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12286. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
6 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
7 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
8 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
9 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
10 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
11 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
12 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
13 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
14 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
15 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
16 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
17 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
18 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
19 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
20 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
21 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
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