G:12349

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Official Symbol Car2
Aliases Ca2, CAII, Car-2, Ltw-5, Lvtw-5, AI131712
EntrezGene 12349
UniProt Coming Soon
Unique Molecular Interactions 132
Total Molecular Interactions 169
Total Single Events 1798
Unique Interaction Partners 97

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Car2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Car2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Car2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
2 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
3 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63
4 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
5 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
6 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05
7 INT110118 A630055G03Rik Regulation of Car2 1 0.01 0.35 0.81
8 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78
9 INT296297 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Car2 1 0.01 0.59 0.77
10 INT170369 Binding of Car2 and Nono 1 0.01 0 0.76
11 INT136538 Nrgn Regulation of Car2 1 0.33 0 0.73
12 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
13 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67
14 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65
15 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
16 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
17 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
18 INT209591 Car2 Positive_regulation of Positive_regulation of Ltp 1 0.05 0 0.54
19 INT209592 Car2 Positive_regulation of Localization of Ltp 1 0.05 0 0.54
20 INT237810 Itpr3 Positive_regulation of Localization of Car2 2 0.08 0.68 0.45
21 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45
22 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45
23 INT265359 Efs Positive_regulation of Car2 1 0.19 0.42 0.45
24 INT291449 Car2 Positive_regulation of SK 1 0.03 0 0.39
25 INT334662 Ltp Regulation of Car2 1 0.09 0.22 0.39
26 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38
27 INT26168 Car2 Positive_regulation of Hrasls 1 0.10 0 0.36
28 INT309192 Binding of Car2 and Rbms1 1 0.05 0 0.34
29 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32
30 INT317557 Calm3 Positive_regulation of Car2 1 0.05 0 0.31
31 INT232614 Positive_regulation of Car2 Positive_regulation of Cysltr1 1 0.01 0.62 0.31
32 INT232616 Car2 Positive_regulation of Cysltr1 1 0.02 0.62 0.31
33 INT209233 Tg(Ngf)47Kma Regulation of Car2 1 0.01 0.1 0.28
34 INT209232 Tg(Ngf)47Kma Regulation of Localization of Car2 1 0.02 0.1 0.28
35 INT250461 Binding of Car2 and Ba2 1 0.01 0 0.26
36 INT209230 Positive_regulation of Car2 Positive_regulation of Ltp 1 0.04 0.12 0.25
37 INT265360 Binding of Car2 and Daf2 1 0.18 0.09 0.22
38 INT248173 Car2 Positive_regulation of GRIN1 1 0.08 0 0.22
39 INT190745 Adcyap1 Regulation of Car2 1 0.08 0 0.21
40 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
41 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2
42 INT80927 Acot1 Positive_regulation of Car2 1 0.31 0 0.2
43 INT212921 Positive_regulation of Binding of Car2 and Tg(CAG-EGFP)D4Nagy 1 0.12 0.22 0.19
44 INT308646 Car2 Regulation of Gene_expression of Ins1 1 0.00 0 0.19
45 INT212920 Binding of Car2 and Tg(CAG-EGFP)D4Nagy 1 0.09 0.22 0.19
46 INT354223 Binding of Car2 and Igfbp7 1 0.02 0.4 0.19
47 INT207640 Binding of Car2 and Nrgn 1 0.04 0 0.18
48 INT328923 Car2 Positive_regulation of Prkca 1 0.00 0 0.18
49 INT69949 Car2 Positive_regulation of MTAP 1 0.02 0.41 0.18
50 INT334769 Ednra Positive_regulation of Car2 1 0.02 0.49 0.18
51 INT351759 Gria2 Regulation of Car2 1 0.07 0.4 0.17
52 INT264277 Binding of Car2 and P2rx1 1 0.10 0 0.16
53 INT190744 Adcyap1 Positive_regulation of Car2 1 0.10 0.08 0.16
54 INT345176 Lpar1 Positive_regulation of Gene_expression of Car2 1 0.03 0.11 0.16
55 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
56 INT334765 Ednra Positive_regulation of Positive_regulation of Car2 1 0.02 0.24 0.14
57 INT180447 Binding of Rhoa and Car2 1 0.17 0.56 0.13
58 INT190743 Adcyap1 Regulation of Gene_expression of Car2 1 0.10 0.06 0.12
59 INT354215 Binding of Car2 and Accn3 1 0.03 0.21 0.1
60 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
61 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
62 INT180449 Rhoa Regulation of Positive_regulation of Car2 1 0.13 0 0.09
63 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
64 INT276039 Positive_regulation of Car2 Positive_regulation of Positive_regulation of Rpa1 1 0.04 0 0.09
65 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09
66 INT215007 Car2 Regulation of Gene_expression of Trpv6 1 0.07 0.25 0.09
67 INT190746 Positive_regulation of Gria2 Positive_regulation of Car2 1 0.00 0.13 0.09
68 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
69 INT217030 Il1 Positive_regulation of Localization of Car2 1 0.00 0 0.08
70 INT251623 Car2 Regulation of Gene_expression of Fig4 1 0.02 0.31 0.08
71 INT217026 Car2 Positive_regulation of Localization of Il1 1 0.00 0 0.08
72 INT215880 Car2 Regulation of Hspa5 1 0.09 0.66 0.08
73 INT237809 Esr1 Positive_regulation of Localization of Car2 1 0.09 0.66 0.07
74 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
75 INT276067 Binding of Car2 and Pde1b 1 0.32 0 0.06
76 INT297214 Myoz1 Regulation of Gene_expression of Car2 1 0.03 0.5 0.06
77 INT212922 Binding of Car2 and Gfm1 1 0.02 0.19 0.06
78 INT297211 Negative_regulation of Myoz1 Negative_regulation of Gene_expression of Car2 1 0.03 0.6 0.05
79 INT333034 Trpv4 Positive_regulation of Localization of Car2 1 0.06 0 0.05
80 INT291451 Binding of CALM1 and Car2 1 0.00 0 0.05
81 INT332325 Car2 Regulation of Pirt 1 0.00 0 0.04
82 INT225735 Car2 Positive_regulation of Entpd2 1 0.01 0.06 0.04
83 INT329222 Positive_regulation of Car2 Regulation of Camkk1 1 0.07 0.08 0.04
84 INT261110 Cir1 Positive_regulation of Car2 1 0.04 0 0.04
85 INT225730 Car2 Positive_regulation of Entpd3 1 0.01 0.06 0.04
86 INT329220 Car2 Regulation of Camkk1 1 0.04 0.08 0.04
87 INT225734 Car2 Positive_regulation of Entpd1 1 0.03 0.06 0.04
88 INT225733 Car2 Positive_regulation of Entpd8 1 0.01 0.06 0.04
89 INT317395 Gopc Regulation of Gene_expression of Car2 2 0.10 0 0.03
90 INT244049 Positive_regulation of Binding of Car2 and Camk2d 1 0.01 0 0.03
91 INT271025 Binding of Car2 and Casq1 1 0.03 0.7 0.03
92 INT180438 Positive_regulation of Rhoa Positive_regulation of Car2 1 0.22 0.48 0.03
93 INT276072 Car2 Regulation of Gene_expression of Rpa1 1 0.03 0 0.03
94 INT334837 Binding of Car2 and Ncs1 1 0.07 0 0.03
95 INT207644 Binding of Car2 and Mtap1b 1 0.04 0 0.03
96 INT244042 Binding of Car2 and Camk2d 1 0.01 0 0.03
97 INT215009 Myoz1 Regulation of Car2 2 0.04 0.1 0
98 INT317393 Binding of Car2 and Ide 1 0.03 0.3 0
99 INT316648 Safb Positive_regulation of Car2 1 0.02 0 0
100 INT180446 Rhoa Regulation of Gene_expression of Car2 1 0.21 0.17 0
101 INT343645 Positive_regulation of Grm5 Positive_regulation of Localization of Car2 1 0.03 0 0
102 INT202894 Binding of Car1 and Car2 1 0.00 0.35 0
103 INT305256 Binding of Car2 and Lipo2 1 0.01 0.89 0
104 INT292384 Itpr3 Regulation of Car2 1 0.07 0 0
105 INT289836 BEST1 Positive_regulation of Gene_expression of Car2 1 0.03 0.08 0
106 INT170562 Car2 Regulation of Narf 1 0.05 1.17 0
107 INT316649 Safb Positive_regulation of Localization of Car2 1 0.02 0 0
108 INT292388 Lrmp Regulation of Car2 1 0.06 0 0
109 INT276035 Regulation of Binding of Car2 and Myoz1 1 0.04 0 0
110 INT170559 Narf Regulation of Gene_expression of Car2 1 0.05 1.01 0
111 INT196406 Car2 Positive_regulation of Ros1 1 0.00 0.69 0
112 INT279695 Hc Negative_regulation of Car2 1 0.02 0 0
113 INT340178 Car2 Positive_regulation of Positive_regulation of Nos3 1 0.01 0.26 0
114 INT340316 Positive_regulation of Bdnf Positive_regulation of Car2 1 0.14 0.06 0
115 INT271026 Binding of Car2 and Dnahc8 1 0.00 0.44 0
116 INT317396 Binding of Car2 and Prkag1 1 0.07 0.31 0
117 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0
118 INT276077 Binding of Camk2a and Car2 1 0.32 0 0
119 INT305259 Binding of Car2 and Obsty1 1 0.02 1.2 0
120 INT276054 Positive_regulation of Car2 Positive_regulation of Rpa1 1 0.04 0 0
121 INT276074 Binding of Car2 and Ppp1cc 1 0.09 0 0
122 INT276051 Pde1b Regulation of Regulation of Car2 1 0.30 0 0
123 INT273291 Atp2a2 Regulation of Car2 1 0.10 0.31 0
124 INT325604 Nppa Regulation of Car2 1 0.23 0 0
125 INT234989 IgG Positive_regulation of Positive_regulation of Car2 1 0.01 0.98 0
126 INT351762 Adarb1 Regulation of Car2 1 0.11 0.68 0
127 INT234993 Binding of Car2 and Dsp 1 0.00 0 0
128 INT271027 Binding of RYR1 and Car2 1 0.03 0.46 0
129 INT273286 Tlx2 Regulation of Car2 1 0.06 0.31 0
130 INT276032 Binding of Car2 and Myoz1 1 0.03 0 0
131 INT305270 Lep Negative_regulation of Localization of Car2 1 0.16 1.28 0
132 INT325611 Nppa Regulation of Gene_expression of Car2 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12349. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12349. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35
2 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76
3 INT17561 Localization of Car2 303 0.79 60.95 44.52
4 INT17962 Regulation of Car2 124 0.41 33.98 22.71
5 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86
6 INT119400 Phosphorylation of Car2 19 0.52 8.47 11.63
7 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24
8 INT29967 Positive_regulation of Positive_regulation of Car2 40 0.40 8.03 10.13
9 INT1129 Binding of Car2 69 0.35 14.01 9.2
10 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45
11 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48
12 INT22160 Negative_regulation of Positive_regulation of Car2 18 0.38 4.94 5.45
13 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1
14 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21
15 INT76468 Regulation of Positive_regulation of Car2 13 0.29 4.54 3.46
16 INT196870 Positive_regulation of Phosphorylation of Car2 6 0.26 3.43 2.63
17 INT146566 Transcription of Car2 8 0.56 1.51 1.6
18 INT60281 Negative_regulation of Negative_regulation of Car2 4 0.36 1.88 1.26
19 INT199386 Negative_regulation of Phosphorylation of Car2 1 0.16 1.37 1.14
20 INT170511 Regulation of Localization of Car2 11 0.21 2.18 1.09
21 INT238532 Negative_regulation of Binding of Car2 4 0.29 0.61 1.07
22 INT146568 Positive_regulation of Transcription of Car2 1 0.31 1.39 0.78
23 INT17964 Negative_regulation of Regulation of Car2 3 0.36 0.58 0.58
24 INT324578 Positive_regulation of Regulation of Car2 1 0.20 0.23 0.49
25 INT250447 Positive_regulation of Binding of Car2 3 0.11 0.36 0.39
26 INT276021 Regulation of Transcription of Car2 2 0.30 0.08 0.36
27 INT81942 Regulation of Regulation of Car2 5 0.29 0.43 0.16
28 INT170552 Regulation of Negative_regulation of Car2 3 0.39 1.97 0.07
29 INT325560 Positive_regulation of Negative_regulation of Car2 2 0.25 0 0.05
30 INT276002 Regulation of Binding of Car2 1 0.35 0 0
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