G:12362

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Official Symbol Casp1
Aliases ICE, Il1bc
EntrezGene 12362
UniProt Coming Soon
Unique Molecular Interactions 20
Total Molecular Interactions 23
Total Single Events 149
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Casp1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Casp1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Casp1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83
2 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8
3 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55
4 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
5 INT90079 Ass1 Positive_regulation of Casp1 1 0.02 0.99 0.43
6 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36
7 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
8 INT69042 Negative_regulation of Casp1 Negative_regulation of Positive_regulation of IL1B 1 0.21 0.17 0.22
9 INT69041 Casp1 Negative_regulation of Gene_expression of IL1B 1 0.21 0.17 0.22
10 INT69040 Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
11 INT69039 Negative_regulation of Casp1 Negative_regulation of Gene_expression of IFNA1 1 0.07 0.17 0.22
12 INT69038 Casp1 Regulation of Gene_expression of IFNA1 1 0.07 0.16 0.18
13 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
14 INT205709 CAMP Positive_regulation of Positive_regulation of Casp1 1 0.00 0.27 0.11
15 INT278376 Negative_regulation of Casp1 Negative_regulation of Hps5 1 0.05 0.05 0.08
16 INT278369 Ctsb Positive_regulation of Casp1 1 0.03 0 0
17 INT226045 Binding of Casp1 and Lta 1 0.04 0.73 0
18 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
19 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0
20 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12362. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12362. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67
2 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52
3 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26
4 INT156876 Positive_regulation of Gene_expression of Casp1 10 0.50 10.25 2.58
5 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44
6 INT69034 Regulation of Casp1 3 0.27 3.56 1.36
7 INT96073 Localization of Casp1 11 0.78 4.91 1.29
8 INT267750 Binding of Casp1 4 0.35 1.53 1.02
9 INT96074 Negative_regulation of Gene_expression of Casp1 4 0.57 2.77 0.87
10 INT205685 Regulation of Positive_regulation of Casp1 3 0.11 1.62 0.78
11 INT182049 Protein_catabolism of Casp1 3 0.20 1.64 0.73
12 INT90078 Negative_regulation of Positive_regulation of Casp1 2 0.42 1.38 0.53
13 INT117939 Transcription of Casp1 1 0.27 0.89 0.4
14 INT117938 Negative_regulation of Transcription of Casp1 1 0.22 0.89 0.4
15 INT298971 Positive_regulation of Localization of Casp1 2 0.06 0.97 0.28
16 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24
17 INT267759 Negative_regulation of Binding of Casp1 1 0.04 0.09 0.1
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