G:12367

Official Symbol Casp3 Aliases CC3, AC-3, Lice, Yama, mldy, CPP32, Apopain, Caspase-3, A830040C14Rik EntrezGene 12367 UniProt Coming Soon

Unique Molecular Interactions 53 Total Molecular Interactions 63 Total Single Events 954 Unique Interaction Partners 41

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Casp3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Casp3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Casp3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT155891	Nps Negative_regulation of Positive_regulation of Casp3	1	0.27	0.17	3.48
2	INT155892	Nps Negative_regulation of Casp3	1	0.27	0.06	1.16
3	INT155890	Nps Negative_regulation of Gene_expression of Casp3	1	0.27	0.05	1.15
4	INT159238	H2-M3 Negative_regulation of Gpm6a Positive_regulation of Casp3	1	0.01	0	1.14
5	INT112607	DNAJC15 Negative_regulation of Positive_regulation of Casp3	1	0.03	0.14	1.12
6	INT159235	H2-M3 Negative_regulation of Casp3	1	0.05	0	1.12
7	INT159236	H2-M3 Positive_regulation of Casp3	1	0.06	0	1.12
8	INT155894	Nps Regulation of Gene_expression of Casp3	1	0.33	0.07	1.09
9	INT74460	GTS Negative_regulation of Casp3	1	0.04	0.37	1.08
10	INT159237	Gpm6a Positive_regulation of Casp3	1	0.03	0	1.07
11	INT307047	Foxm1 Positive_regulation of Casp3	1	0.11	0.06	1.03
12	INT98556	Oprm1 Positive_regulation of Casp3	1	0.38	0.36	1.01
13	INT155893	Nps Regulation of Casp3	1	0.24	0.08	0.95
14	INT148806	Diablo Positive_regulation of Positive_regulation of Casp3	1	0.03	1.02	0.89
15	INT147885	Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3	1	0.13	0	0.88
16	INT307045	Tmie Negative_regulation of Positive_regulation of Casp3	1	0.01	0.29	0.85
17	INT307044	Tmie Regulation of Casp3	1	0.01	0	0.75
18	INT114860	Negative_regulation of Insrr Positive_regulation of Casp3	1	0.02	0.71	0.73
19	INT114505	Negative_regulation of Hmmr Positive_regulation of Casp3	1	0.01	0.72	0.6
20	INT114506	Hmmr Positive_regulation of Casp3	1	0.01	0.72	0.6
21	INT163376	RYBP Positive_regulation of Gene_expression of Casp3	2	0.01	0.57	0.59
22	INT307048	Cnr1 Positive_regulation of Casp3	1	0.08	0	0.47
23	INT145908	Pdyn Regulation of Positive_regulation of Casp3	1	0.14	0.94	0.37
24	INT286708	Negative_regulation of Mapk1 Negative_regulation of Casp3	1	0.12	0	0.31
25	INT166162	Ccr9 Negative_regulation of Positive_regulation of Casp3	1	0.18	1.49	0.28
26	INT148629	Binding of Cat and Casp3	1	0.08	0.09	0.26
27	INT149713	Binding of Casp3 and Fas	1	0.40	1.09	0.25
28	INT201754	CASP8 Positive_regulation of Casp3	1	0.00	0.47	0.12
29	INT234062	Nes Positive_regulation of Casp3	1	0.18	0.08	0.11
30	INT203849	Ass1 Positive_regulation of Casp3	1	0.00	0.71	0.07
31	INT211347	Binding of Sigmar1 and Positive_regulation of Casp3	1	0.12	0.92	0.06
32	INT242411	Mch Positive_regulation of Casp3	1	0.09	0.15	0.04
33	INT302983	Fadd Positive_regulation of Casp3	1	0.15	1.13	0.04
34	INT242413	Regulation of Mch Positive_regulation of Casp3	1	0.05	0.16	0.04
35	INT267217	Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3	1	0.14	2.8	0.04
36	INT322358	Binding of Parp1 and Casp3	1	0.05	1.08	0.04
37	INT172897	Negative_regulation of Lox Positive_regulation of Positive_regulation of Casp3	1	0.04	1.19	0.03
38	INT172910	Lox Positive_regulation of Positive_regulation of Casp3	1	0.03	1.19	0.03
39	INT345350	Casp3 Positive_regulation of Prkcd	1	0.05	0.79	0.03
40	INT277693	Stat6 Positive_regulation of Positive_regulation of Casp3	1	0.01	1.01	0
41	INT333772	Positive_regulation of Casp3 Positive_regulation of Gga3	1	0.05	0.5	0
42	INT333696	Tpsg1 Positive_regulation of Casp3	1	0.08	3.18	0
43	INT157755	Tmx1 Regulation of Positive_regulation of Casp3	1	0.15	0	0
44	INT277691	Cdkn1a Negative_regulation of Positive_regulation of Casp3	1	0.00	1.01	0
45	INT333771	Casp3 Positive_regulation of Gga3	1	0.05	0.5	0
46	INT226042	Binding of Casp1 and Casp3	1	0.02	0.73	0
47	INT268633	Mpz Positive_regulation of Positive_regulation of Casp3	1	0.14	0	0
48	INT157754	Tmx1 Regulation of Gene_expression of Casp3	1	0.15	0	0
49	INT322365	TNF Positive_regulation of Positive_regulation of Casp3	1	0.01	1.54	0
50	INT333698	Gene_expression of Hr Negative_regulation of Casp3	1	0.14	0.73	0
51	INT201755	ROS1 Positive_regulation of Casp3	1	0.00	1.4	0
52	INT263335	Olfm4 Regulation of Regulation of Casp3	1	0.00	0.33	0
53	INT319170	Casp3 Regulation of Hdac1	1	0.01	0.27	0
54	INT277694	Cdkn1a Positive_regulation of Positive_regulation of Casp3	1	0.00	1.01	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12367. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12367. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT65600	Positive_regulation of Casp3	376	0.70	198.44	128.03
2	INT31116	Gene_expression of Casp3	192	0.78	78.21	57.43
3	INT65597	Negative_regulation of Casp3	69	0.59	39.19	29.32
4	INT65598	Negative_regulation of Positive_regulation of Casp3	45	0.59	18.36	28.59
5	INT78694	Positive_regulation of Gene_expression of Casp3	46	0.66	18.64	19.62
6	INT78697	Negative_regulation of Gene_expression of Casp3	33	0.57	11.22	16.16
7	INT81626	Positive_regulation of Positive_regulation of Casp3	34	0.69	16.75	12.18
8	INT78695	Regulation of Casp3	24	0.44	9.43	10.48
9	INT105103	Regulation of Gene_expression of Casp3	11	0.39	3.15	9.22
10	INT78696	Regulation of Positive_regulation of Casp3	9	0.39	2.93	8.2
11	INT31118	Localization of Casp3	17	0.73	11.55	2.3
12	INT102532	Protein_catabolism of Casp3	24	0.64	16.78	1.64
13	INT31117	Binding of Casp3	14	0.23	5.27	0.93
14	INT242061	Positive_regulation of Negative_regulation of Casp3	3	0.09	1.7	0.58
15	INT153436	Positive_regulation of Localization of Casp3	3	0.49	2.12	0.43
16	INT155293	Positive_regulation of Protein_catabolism of Casp3	3	0.45	1.7	0.4
17	INT165916	Negative_regulation of Localization of Casp3	2	0.41	2.41	0.34
18	INT123522	Phosphorylation of Casp3	3	0.80	1.36	0.14
19	INT226041	Positive_regulation of Binding of Casp3	1	0.12	0.82	0.12
20	INT288609	Regulation of Regulation of Casp3	1	0.05	0.69	0.07
21	INT333205	Negative_regulation of Protein_catabolism of Casp3	1	0.04	0.6	0.05
22	INT304140	Regulation of Negative_regulation of Casp3	1	0.05	0.67	0
23	INT159172	Negative_regulation of Negative_regulation of Casp3	1	0.09	0.07	0
24	INT228785	Positive_regulation of Transcription of Casp3	1	0.17	0.06	0
25	INT228792	Transcription of Casp3	1	0.24	0.05	0