G:12367

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Official Symbol Casp3
Aliases CC3, AC-3, Lice, Yama, mldy, CPP32, Apopain, Caspase-3, A830040C14Rik
EntrezGene 12367
UniProt Coming Soon
Unique Molecular Interactions 53
Total Molecular Interactions 63
Total Single Events 954
Unique Interaction Partners 41

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Casp3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Casp3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Casp3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
3 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
4 INT159238 H2-M3 Negative_regulation of Gpm6a Positive_regulation of Casp3 1 0.01 0 1.14
5 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
6 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
7 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
8 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
9 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
10 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
11 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
12 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
13 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
14 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
15 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
16 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
17 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
18 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
19 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
20 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
21 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
22 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
23 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
24 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
25 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
26 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
27 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
28 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
29 INT234062 Nes Positive_regulation of Casp3 1 0.18 0.08 0.11
30 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07
31 INT211347 Binding of Sigmar1 and Positive_regulation of Casp3 1 0.12 0.92 0.06
32 INT242411 Mch Positive_regulation of Casp3 1 0.09 0.15 0.04
33 INT302983 Fadd Positive_regulation of Casp3 1 0.15 1.13 0.04
34 INT242413 Regulation of Mch Positive_regulation of Casp3 1 0.05 0.16 0.04
35 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04
36 INT322358 Binding of Parp1 and Casp3 1 0.05 1.08 0.04
37 INT172897 Negative_regulation of Lox Positive_regulation of Positive_regulation of Casp3 1 0.04 1.19 0.03
38 INT172910 Lox Positive_regulation of Positive_regulation of Casp3 1 0.03 1.19 0.03
39 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03
40 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0
41 INT333772 Positive_regulation of Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
42 INT333696 Tpsg1 Positive_regulation of Casp3 1 0.08 3.18 0
43 INT157755 Tmx1 Regulation of Positive_regulation of Casp3 1 0.15 0 0
44 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
45 INT333771 Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
46 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0
47 INT268633 Mpz Positive_regulation of Positive_regulation of Casp3 1 0.14 0 0
48 INT157754 Tmx1 Regulation of Gene_expression of Casp3 1 0.15 0 0
49 INT322365 TNF Positive_regulation of Positive_regulation of Casp3 1 0.01 1.54 0
50 INT333698 Gene_expression of Hr Negative_regulation of Casp3 1 0.14 0.73 0
51 INT201755 ROS1 Positive_regulation of Casp3 1 0.00 1.4 0
52 INT263335 Olfm4 Regulation of Regulation of Casp3 1 0.00 0.33 0
53 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
54 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12367. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12367. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
2 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
3 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
4 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
5 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
6 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
7 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
8 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
9 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
10 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
11 INT31118 Localization of Casp3 17 0.73 11.55 2.3
12 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
13 INT31117 Binding of Casp3 14 0.23 5.27 0.93
14 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
15 INT153436 Positive_regulation of Localization of Casp3 3 0.49 2.12 0.43
16 INT155293 Positive_regulation of Protein_catabolism of Casp3 3 0.45 1.7 0.4
17 INT165916 Negative_regulation of Localization of Casp3 2 0.41 2.41 0.34
18 INT123522 Phosphorylation of Casp3 3 0.80 1.36 0.14
19 INT226041 Positive_regulation of Binding of Casp3 1 0.12 0.82 0.12
20 INT288609 Regulation of Regulation of Casp3 1 0.05 0.69 0.07
21 INT333205 Negative_regulation of Protein_catabolism of Casp3 1 0.04 0.6 0.05
22 INT304140 Regulation of Negative_regulation of Casp3 1 0.05 0.67 0
23 INT159172 Negative_regulation of Negative_regulation of Casp3 1 0.09 0.07 0
24 INT228785 Positive_regulation of Transcription of Casp3 1 0.17 0.06 0
25 INT228792 Transcription of Casp3 1 0.24 0.05 0
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