G:12370

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Official Symbol Casp8
Aliases MACH, Mch5, FLICE, CASP-8
EntrezGene 12370
UniProt Coming Soon
Unique Molecular Interactions 11
Total Molecular Interactions 12
Total Single Events 71
Unique Interaction Partners 10

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Casp8. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Casp8. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Casp8. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
2 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
3 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58
4 INT349539 Smcp Positive_regulation of Positive_regulation of Casp8 1 0.04 0.68 0.18
5 INT349540 Tnfsf10 Positive_regulation of Positive_regulation of Casp8 1 0.05 0.65 0.15
6 INT251565 Binding of Casp8 and Fadd 1 0.04 1.18 0.04
7 INT251570 Binding of Casp8 and Faf1 1 0.01 1.18 0.04
8 INT261123 Tnfsf10 Positive_regulation of Casp8 1 0.04 1 0
9 INT270657 Casp8 Regulation of Localization of Ins1 1 0.03 0.68 0
10 INT342854 Binding of Casp8 and Mapk1 1 0.05 2.18 0
11 INT342852 Binding of Casp8 and Dedd2 1 0.01 1.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12370. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12370. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9
2 INT109970 Negative_regulation of Casp8 5 0.52 9.34 2.19
3 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13
4 INT156875 Positive_regulation of Gene_expression of Casp8 2 0.49 2.49 0.7
5 INT142872 Regulation of Casp8 6 0.29 3.11 0.39
6 INT167206 Positive_regulation of Positive_regulation of Casp8 4 0.49 2.11 0.26
7 INT116193 Protein_catabolism of Casp8 5 0.17 4.37 0.17
8 INT199848 Binding of Casp8 3 0.15 3.29 0.09
9 INT256923 Regulation of Gene_expression of Casp8 2 0.11 2.31 0.04
10 INT199851 Positive_regulation of Protein_catabolism of Casp8 1 0.07 1.04 0.04
11 INT292858 Localization of Casp8 2 0.27 1.68 0.03
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