G:12487

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Official Symbol Cd28
Aliases none
EntrezGene 12487
UniProt Coming Soon
Unique Molecular Interactions 34
Total Molecular Interactions 57
Total Single Events 105
Unique Interaction Partners 24

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cd28. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cd28. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cd28. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49
2 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
3 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05
4 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98
5 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
6 INT103937 Cps1 Negative_regulation of Gene_expression of Cd28 1 0.03 0.19 0.51
7 INT287819 Binding of CD80 and Cd28 1 0.25 0.7 0.4
8 INT287818 Negative_regulation of Binding of CD80 and Cd28 1 0.29 0.7 0.4
9 INT222212 TFAM Negative_regulation of Cd28 1 0.02 1.17 0.39
10 INT299780 Binding of Cd28 and Cd80 1 0.21 1.36 0.34
11 INT238006 Cxcl10 Positive_regulation of Gene_expression of Cd28 1 0.24 0.91 0.21
12 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17
13 INT265215 Cd28 Regulation of Transcription of thd 1 0.00 0 0.15
14 INT188356 Binding of Cd28 and Positive_regulation of Localization of Cd4 1 0.30 0.18 0.11
15 INT299782 Cd28 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
16 INT188360 Binding of Cd28 and Positive_regulation of Localization of Cd8a 1 0.09 0.18 0.11
17 INT265212 Cd28 Negative_regulation of Gene_expression of Il17a 1 0.10 0 0.09
18 INT265222 Binding of Cd28 and Gopc 1 0.04 0 0.08
19 INT265221 Binding of Cd28 and Positive_regulation of Gene_expression of Il17a 1 0.15 0.09 0.08
20 INT174561 Binding of Cd28 and Ncl 1 0.00 0.62 0.07
21 INT252353 Regulation of Binding of LCP2 and Cd28 1 0.37 0 0.06
22 INT252355 Binding of LCP2 and Cd28 1 0.30 0 0.06
23 INT252338 Binding of Cd28 and Lat 1 0.30 0 0.06
24 INT237192 Cd28 Positive_regulation of LPT 1 0.01 0.15 0.06
25 INT252335 Regulation of Binding of Cd28 and Lat 1 0.37 0 0.06
26 INT265224 Cd28 Positive_regulation of Gene_expression of IFN1@ 1 0.34 0.25 0.05
27 INT265218 Cd28 Positive_regulation of Gene_expression of Gopc 1 0.06 0.25 0.05
28 INT265225 Cd28 Positive_regulation of IFN1@ 1 0.47 0.25 0.05
29 INT299762 Binding of Cd28 and Positive_regulation of Gene_expression of Il2 1 0.03 0.07 0.04
30 INT252354 TNF Negative_regulation of Cd28 1 0.05 0.48 0
31 INT273716 Binding of Cd28 and Icam1 1 0.09 0 0
32 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0
33 INT265223 Negative_regulation of Binding of Ctla4 and Cd28 1 0.18 0.14 0
34 INT252350 Binding of Cd86 and Apcs Positive_regulation of Cd28 1 0.10 0.3 0
35 INT265216 Cd28 Positive_regulation of Gene_expression of Il17a 1 0.10 0 0
36 INT252351 Binding of Cd80 and Apcs Positive_regulation of Cd28 1 0.07 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12487. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12487. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75
2 INT188355 Binding of Cd28 25 0.34 8.29 3.38
3 INT94126 Positive_regulation of Cd28 9 0.50 4.23 1.33
4 INT174557 Negative_regulation of Gene_expression of Cd28 7 0.43 4.42 1.2
5 INT174550 Negative_regulation of Cd28 7 0.33 4.7 1.06
6 INT265207 Positive_regulation of Gene_expression of Cd28 3 0.43 1.47 0.66
7 INT174556 Regulation of Gene_expression of Cd28 3 0.42 2.9 0.57
8 INT287809 Negative_regulation of Positive_regulation of Cd28 1 0.26 0.65 0.38
9 INT252317 Negative_regulation of Binding of Cd28 3 0.31 1.09 0.21
10 INT220835 Localization of Cd28 1 0.65 0.45 0.2
11 INT220837 Regulation of Cd28 2 0.41 0.14 0.19
12 INT220838 Protein_catabolism of Cd28 1 0.60 0.46 0.16
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