G:12568

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Official Symbol Cdk5
Aliases Crk6, AW048668
EntrezGene 12568
UniProt Coming Soon
Unique Molecular Interactions 28
Total Molecular Interactions 36
Total Single Events 204
Unique Interaction Partners 16

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cdk5. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cdk5. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cdk5. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
2 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
3 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
4 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
5 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
6 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
7 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
8 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
9 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
10 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
11 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
12 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
13 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
14 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
15 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
16 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
17 INT332329 Binding of Cdk5 and P2rx3 1 0.22 0.05 0.05
18 INT332331 Binding of Cdk5 and Rbm39 1 0.00 0.05 0.05
19 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
20 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
21 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
22 INT332330 Cdk5 Negative_regulation of Pirt 1 0.00 0 0.03
23 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03
24 INT221666 Sema3a Positive_regulation of Fyn Positive_regulation of Cdk5 1 0.10 0.29 0.03
25 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03
26 INT201734 Binding of Akt1 and Cdk5 1 0.01 0.31 0
27 INT201738 Positive_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
28 INT201731 Negative_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
29 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12568. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12568. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
2 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
3 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
4 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
5 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
6 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
7 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
8 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
9 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
10 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
11 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
12 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
13 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
14 INT326820 Negative_regulation of Positive_regulation of Cdk5 1 0.36 1.27 0.28
15 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28
16 INT273226 Negative_regulation of Gene_expression of Cdk5 2 0.42 0.79 0.17
17 INT326822 Negative_regulation of Phosphorylation of Cdk5 1 0.36 0.43 0.12
18 INT201655 Negative_regulation of Binding of Cdk5 1 0.06 0.9 0.09
19 INT268444 Regulation of Positive_regulation of Cdk5 1 0.08 0.66 0
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