G:12576

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Official Symbol Cdkn1b
Aliases p27, Kip1, p27Kip1, AA408329, AI843786
EntrezGene 12576
UniProt Coming Soon
Unique Molecular Interactions 20
Total Molecular Interactions 27
Total Single Events 185
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cdkn1b. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cdkn1b. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cdkn1b. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
2 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
3 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
4 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
5 INT295045 Akt1 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.09 2.06 0
6 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
7 INT322536 Negative_regulation of Ctsb Positive_regulation of Gene_expression of Cdkn1b 1 0.02 0.3 0
8 INT322547 FOXO3 Regulation of Transcription of Cdkn1b 1 0.12 0.32 0
9 INT295050 Protein_catabolism of Cdkn1b Positive_regulation of Akt1 Positive_regulation of Cdk2 1 0.05 1.03 0
10 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0
11 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
12 INT322548 FOXO3 Regulation of Cdkn1b 1 0.09 0.23 0
13 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
14 INT322540 Positive_regulation of Plaur Regulation of Gene_expression of Cdkn1b 1 0.06 0 0
15 INT322537 Ctsb Regulation of Gene_expression of Cdkn1b 1 0.01 0.1 0
16 INT276336 Skp2 Regulation of Cdkn1b 1 0.00 0.57 0
17 INT322538 Plaur Regulation of Cdkn1b 1 0.14 0.19 0
18 INT276335 Binding of Cdkn1b and Skp2 1 0.00 0.57 0
19 INT220519 Ugt1a6b Positive_regulation of Negative_regulation of Cdkn1b 1 0.01 0.24 0
20 INT322539 Ctsb Regulation of Cdkn1b 1 0.03 0.19 0
21 INT220523 Ugt1a6b Positive_regulation of Gene_expression of Cdkn1b 1 0.01 0.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12576. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12576. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
2 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
3 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
4 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
5 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
6 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
7 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
8 INT179043 Negative_regulation of Cdkn1b 7 0.36 5.99 0.22
9 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18
10 INT179034 Binding of Cdkn1b 7 0.31 5.12 0.12
11 INT220494 Negative_regulation of Positive_regulation of Cdkn1b 1 0.14 0.35 0.1
12 INT179033 Negative_regulation of Regulation of Cdkn1b 1 0.36 1.34 0.05
13 INT220489 Regulation of Gene_expression of Cdkn1b 1 0.20 1.57 0.04
14 INT123524 Phosphorylation of Cdkn1b 4 0.29 2.29 0
15 INT276307 Protein_catabolism of Cdkn1b 2 0.45 2.57 0
16 INT295040 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.21 1 0
17 INT322505 Transcription of Cdkn1b 1 0.26 1.02 0
18 INT322508 Regulation of Localization of Cdkn1b 1 0.10 0.4 0
19 INT322519 Negative_regulation of Transcription of Cdkn1b 1 0.16 0.07 0
20 INT322517 Positive_regulation of Transcription of Cdkn1b 1 0.17 0.64 0
21 INT276316 Positive_regulation of Negative_regulation of Cdkn1b 1 0.07 0.56 0
22 INT322506 Negative_regulation of Phosphorylation of Cdkn1b 1 0.16 0.07 0
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