G:12675

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Official Symbol Chuk
Aliases IKK1, Ikka, Chuk1, Fbx24, IKBKA, Fbxo24, NFKBIKA, AI256658, MGC25325
EntrezGene 12675
UniProt Coming Soon
Unique Molecular Interactions 22
Total Molecular Interactions 50
Total Single Events 185
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Chuk. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Chuk. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Chuk. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
2 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29
3 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29
4 INT324801 Positive_regulation of Binding of Chuk and Irak1 1 0.03 0.86 0.28
5 INT324825 Binding of Chuk and Myd88 1 0.03 0.86 0.28
6 INT324810 Binding of Chuk and Irak1 1 0.02 0.85 0.28
7 INT324806 Positive_regulation of Binding of Chuk and Myd88 1 0.04 0.86 0.28
8 INT143725 Chuk Negative_regulation of Phosphorylation of Nfkb1 1 0.17 0.71 0.26
9 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
10 INT311989 Binding of Chuk and Mthfd1 1 0.05 0.56 0.24
11 INT222874 NDUFA6 Regulation of Chuk 1 0.01 1.57 0.15
12 INT222876 Binding of NDUFA6 and Chuk 1 0.02 2.02 0.13
13 INT222875 Binding of NDUFA6 and Positive_regulation of Chuk 1 0.01 0.74 0.13
14 INT222873 NDUFA6 Negative_regulation of Phosphorylation of Chuk 1 0.01 0.24 0.08
15 INT163618 Chuk Regulation of Rela 1 0.16 0.23 0.08
16 INT222878 NDUFA6 Negative_regulation of Chuk 1 0.01 2.06 0.05
17 INT348024 Binding of Chuk and Traf3 1 0.13 0.65 0.04
18 INT348018 Map3k7 Positive_regulation of Chuk 1 0.19 0.06 0
19 INT222868 Binding of Chuk and Pkn1 1 0.00 0 0
20 INT222871 Binding of Chuk and Ikbkg 1 0.02 0 0
21 INT348035 Map3k7 Positive_regulation of Binding of Chuk 1 0.20 0.06 0
22 INT222870 Traf2 Positive_regulation of Chuk 1 0.03 0.37 0
23 INT222864 NDUFA6 Negative_regulation of Binding of NDUFA6 and Chuk 1 0.00 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12675. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12675. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113700 Positive_regulation of Chuk 30 0.41 21.17 5.69
2 INT174958 Negative_regulation of Chuk 21 0.25 8.73 2.96
3 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67
4 INT143716 Phosphorylation of Chuk 16 0.41 5.25 1.35
5 INT217438 Binding of Chuk 24 0.25 7.29 1.29
6 INT143713 Positive_regulation of Phosphorylation of Chuk 4 0.25 1.38 0.58
7 INT202494 Regulation of Chuk 5 0.20 2.17 0.46
8 INT222850 Positive_regulation of Gene_expression of Chuk 7 0.34 4.91 0.44
9 INT222838 Negative_regulation of Gene_expression of Chuk 5 0.25 3.43 0.31
10 INT278145 Positive_regulation of Positive_regulation of Chuk 2 0.29 1.45 0.28
11 INT222844 Positive_regulation of Binding of Chuk 1 0.13 0.58 0.26
12 INT206047 Negative_regulation of Positive_regulation of Chuk 2 0.11 0.6 0.23
13 INT222836 Negative_regulation of Phosphorylation of Chuk 5 0.16 0.98 0.19
14 INT222837 Regulation of Binding of Chuk 1 0.12 1.18 0.18
15 INT302181 Positive_regulation of Negative_regulation of Chuk 1 0.04 0.54 0.16
16 INT243679 Protein_catabolism of Chuk 1 0.02 0 0.14
17 INT202489 Localization of Chuk 3 0.53 1.63 0.08
18 INT202479 Positive_regulation of Localization of Chuk 1 0.35 0.33 0
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