G:12767

From wiki-pain
Jump to: navigation, search
Official Symbol Cxcr4
Aliases CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, PBSF/SDF-1
EntrezGene 12767
UniProt Coming Soon
Unique Molecular Interactions 39
Total Molecular Interactions 55
Total Single Events 250
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cxcr4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cxcr4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cxcr4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT353362 amd Negative_regulation of Cxcr4 1 0.04 0.52 0.33
2 INT226716 Binding of Cxcr4 and Sdf2l1 2 0.30 1.42 0.32
3 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
4 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
5 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
6 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
7 INT226759 Serpinf1 Negative_regulation of Cxcr4 1 0.01 0.58 0.17
8 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
9 INT226712 Sdf2l1 Positive_regulation of Negative_regulation of Cxcr4 1 0.02 1.34 0.13
10 INT182477 Binding of Akt1 and Cxcr4 1 0.10 0.12 0.13
11 INT182484 Binding of Akt1 and Cxcr4 Positive_regulation of Akt1 1 0.06 0.12 0.13
12 INT326380 Binding of Cxcr4 and Podxl 1 0.05 0.36 0.12
13 INT284218 Binding of Cxcr4 and Avpr1b 1 0.00 0.46 0.12
14 INT226766 Sdf2l1 Regulation of Binding of Cxcr4 and Sdf2l1 1 0.00 0.48 0.1
15 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09
16 INT273655 Binding of FUT1 and Cxcr4 1 0.07 0.41 0.09
17 INT226746 Cxcr4 Regulation of Protein_catabolism of Vps28 1 0.08 0.35 0.07
18 INT226729 Cxcr4 Regulation of Vps28 1 0.08 0.35 0.07
19 INT226763 Binding of Cxcr4 and Vps28 1 0.07 0.35 0.07
20 INT273653 Cxcr4 Negative_regulation of Binding of FUT1 1 0.08 0.21 0.06
21 INT332795 Negative_regulation of Vhl Positive_regulation of Positive_regulation of Cxcr4 1 0.02 1.64 0.05
22 INT226728 Tnip1 Regulation of Cxcr4 1 0.04 0.66 0
23 INT280262 Binding of Tgfb1 and Positive_regulation of Cxcr4 1 0.07 1.27 0
24 INT226722 Cxcr4 Positive_regulation of Protein_catabolism of Sdf2l1 1 0.02 0.3 0
25 INT273652 Cxcr4 Regulation of Binding of FUT1 1 0.08 0.22 0
26 INT226765 Sdf2l1 Negative_regulation of Cxcr4 Negative_regulation of Cd4 1 0.01 0.43 0
27 INT226739 Tsg101 Regulation of Negative_regulation of Cxcr4 1 0.13 0.69 0
28 INT226762 Gene_expression of Hivan1 Positive_regulation of Cxcr4 1 0.01 0.25 0
29 INT280265 Binding of Cxcr4 and Tgfb1 1 0.06 0.89 0
30 INT226743 Binding of Cxcr4 and Hivan1 1 0.01 1.03 0
31 INT226710 Binding of Cxcr4 and Mela 1 0.02 1.03 0
32 INT226747 Mela Positive_regulation of Gene_expression of Cxcr4 1 0.03 1.01 0
33 INT280272 VEGFA Regulation of Cxcr4 1 0.05 0.87 0
34 INT226755 Cxcr4 Negative_regulation of Cd4 1 0.15 0.38 0
35 INT280269 Tgfb1 Regulation of Cxcr4 1 0.04 0.88 0
36 INT226753 Hivan1 Positive_regulation of Negative_regulation of Cxcr4 1 0.01 0.81 0
37 INT226718 Sdf2l1 Negative_regulation of Cxcr4 1 0.02 0.62 0
38 INT226723 Sdf2l1 Positive_regulation of Protein_catabolism of Cxcr4 1 0.03 1.93 0
39 INT280264 Negative_regulation of Binding of Cxcr4 and Tgfb1 1 0.07 0.89 0
40 INT226754 Mela Regulation of Cxcr4 1 0.02 0.66 0
41 INT226730 Tnip1 Positive_regulation of Negative_regulation of Cxcr4 1 0.06 0.81 0
42 INT347957 Binding of PTPRC and Cxcr4 1 0.39 0.37 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12767. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12767. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6
2 INT226637 Negative_regulation of Cxcr4 41 0.48 24.42 1.91
3 INT126476 Positive_regulation of Cxcr4 25 0.69 19.01 1.72
4 INT182629 Binding of Cxcr4 12 0.36 5.24 1.47
5 INT226691 Positive_regulation of Gene_expression of Cxcr4 14 0.57 7.9 0.9
6 INT167677 Localization of Cxcr4 8 0.58 6.61 0.76
7 INT126479 Regulation of Cxcr4 11 0.58 10.75 0.34
8 INT226649 Positive_regulation of Positive_regulation of Cxcr4 4 0.39 3.83 0.32
9 INT226647 Negative_regulation of Gene_expression of Cxcr4 4 0.40 3.31 0.31
10 INT273642 Negative_regulation of Binding of Cxcr4 2 0.35 0.35 0.13
11 INT226668 Positive_regulation of Negative_regulation of Cxcr4 1 0.29 2.77 0.13
12 INT226639 Phosphorylation of Cxcr4 1 0.47 0.64 0.1
13 INT226634 Protein_catabolism of Cxcr4 1 0.57 6.83 0.08
14 INT165212 Regulation of Gene_expression of Cxcr4 4 0.48 1.33 0
15 INT226677 Regulation of Negative_regulation of Cxcr4 3 0.25 2.54 0
16 INT226654 Negative_regulation of Negative_regulation of Cxcr4 1 0.34 3.39 0
17 INT280237 Negative_regulation of Positive_regulation of Cxcr4 1 0.33 0.75 0
18 INT347956 Negative_regulation of Regulation of Cxcr4 1 0.40 1.25 0
19 INT226662 Negative_regulation of Protein_catabolism of Cxcr4 1 0.25 0.37 0
20 INT226701 Transcription of Cxcr4 1 0.40 0 0
21 INT226686 Regulation of Positive_regulation of Cxcr4 1 0.26 0.46 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox