G:12912

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Official Symbol Creb1
Aliases Creb, Creb-1, AV083133, 2310001E10Rik, 3526402H21Rik
EntrezGene 12912
UniProt Coming Soon
Unique Molecular Interactions 92
Total Molecular Interactions 115
Total Single Events 1101
Unique Interaction Partners 59

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Creb1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Creb1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Creb1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
2 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
3 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
4 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
5 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
6 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
7 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
8 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
9 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
10 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
11 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
12 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
13 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
14 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
15 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
16 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
17 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
18 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57
19 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
20 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
21 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
22 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53
23 INT305731 Binding of Bdnf and Creb1 Positive_regulation of BDNF 1 0.11 0.49 0.47
24 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
25 INT305747 Binding of Bdnf and Creb1 Positive_regulation of Bdnf 1 0.03 0.49 0.47
26 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
27 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
28 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
29 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
30 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
31 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4
32 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4
33 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39
34 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38
35 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
36 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36
37 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
38 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
39 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32
40 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
41 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32
42 INT186152 Camk4 Regulation of Phosphorylation of Creb1 3 0.27 0.44 0.29
43 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28
44 INT296284 Calm3 Regulation of Positive_regulation of Creb1 1 0.09 0.31 0.28
45 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28
46 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28
47 INT283733 Trib3 Positive_regulation of Creb1 1 0.00 0 0.28
48 INT296287 Camk4 Regulation of Positive_regulation of Creb1 1 0.27 0.31 0.27
49 INT186151 Camk4 Regulation of Creb1 2 0.27 1.06 0.25
50 INT169049 Positive_regulation of Binding of Creb1 and Sult4a1 1 0.47 0.11 0.24
51 INT169051 Binding of Creb1 and Sult4a1 1 0.32 0.11 0.24
52 INT257233 PRKG1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0.09 0.2
53 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
54 INT57383 Binding of Creb1 and Penk 1 0.05 0.67 0.2
55 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
56 INT156970 Negative_regulation of Kcnip3 Positive_regulation of Transcription of Creb1 1 0.47 0.45 0.17
57 INT156971 Kcnip3 Negative_regulation of Creb1 1 0.48 0.46 0.17
58 INT103889 Pdyn Regulation of Gene_expression of Creb1 1 0.03 0.19 0.15
59 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13
60 INT201749 Creb1 Positive_regulation of Ngf 1 0.03 0.33 0.13
61 INT264835 Binding of Creb1 and Tpr 1 0.01 0.05 0.06
62 INT273944 Negative_regulation of Creb1 Positive_regulation of Positive_regulation of Crem 1 0.26 0.62 0.05
63 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
64 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
65 INT186147 Camk4 Regulation of Regulation of Creb1 1 0.45 0.95 0.04
66 INT272728 Binding of Creb1 and Jun 1 0.00 0.09 0.04
67 INT240905 Gene_expression of Sod1 Negative_regulation of Phosphorylation of Creb1 1 0.32 0.1 0.03
68 INT240894 Gcg Positive_regulation of Creb1 1 0.14 0.06 0.03
69 INT273946 Phosphorylation of Creb1 Positive_regulation of Gene_expression of Crem 1 0.29 0 0
70 INT273938 Creb1 Positive_regulation of Transcription of Mirg 1 0.01 0.06 0
71 INT225565 Ncoa6 Regulation of Creb1 1 0.06 0.21 0
72 INT286730 Creb1 Regulation of Ppargc1a 1 0.17 0 0
73 INT273948 Binding of Creb1 and Pmp2 1 0.04 0 0
74 INT240878 Creb1 Positive_regulation of Ppargc1a 1 0.19 0.11 0
75 INT240908 Negative_regulation of Ros1 Positive_regulation of Creb1 1 0.17 0.18 0
76 INT273952 Creb1 Positive_regulation of Pmp2 1 0.09 0.06 0
77 INT57382 Creb1 Regulation of Gene_expression of Penk 1 0.06 0.51 0
78 INT240898 Mapk1 Regulation of Phosphorylation of Creb1 1 0.11 0.17 0
79 INT333854 Binding of SOD1 and Creb1 1 0.02 0 0
80 INT273943 Creb1 Positive_regulation of Transcription of Crem 1 0.44 0.07 0
81 INT240907 Mapk14 Positive_regulation of Creb1 1 0.13 0.34 0
82 INT333845 Igf1 Positive_regulation of Gene_expression of Creb1 1 0.21 0.13 0
83 INT207210 Binding of Creb1 and Cytip 1 0.18 0.33 0
84 INT240904 Ros1 Positive_regulation of Creb1 1 0.20 0.18 0
85 INT240895 Mapk14 Regulation of Phosphorylation of Creb1 1 0.12 0.17 0
86 INT57385 Binding of PENK and Creb1 1 0.33 0.59 0
87 INT191066 Akt1 Positive_regulation of Creb1 1 0.11 0.33 0
88 INT273957 Binding of Creb1 and Pmp2 Positive_regulation of Gene_expression of Crem 1 0.06 0 0
89 INT240882 Sod1 Positive_regulation of Phosphorylation of Creb1 1 0.31 0.1 0
90 INT240869 Ros1 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.9 0
91 INT57384 Binding of FOS and Creb1 1 0.29 0.59 0
92 INT225527 Ncoa6 Positive_regulation of Creb1 1 0.12 0 0
93 INT221467 Binding of Creb1 and Dusp1 1 0.10 0 0
94 INT273951 Phosphorylation of Creb1 Positive_regulation of Pmp2 1 0.06 0.06 0
95 INT273942 Creb1 Positive_regulation of Gene_expression of Crem 1 0.29 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12912. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12912. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
2 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
3 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
4 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
5 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
6 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
7 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
8 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
9 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
10 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
11 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
12 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
13 INT92971 Binding of Creb1 31 0.47 11.3 6.22
14 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
15 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
16 INT121866 Localization of Creb1 13 0.73 1.95 4.48
17 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
18 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
19 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
20 INT169721 Negative_regulation of Negative_regulation of Creb1 1 0.43 0.09 1.22
21 INT121867 Positive_regulation of Localization of Creb1 2 0.60 0.43 1.2
22 INT207201 Positive_regulation of Transcription of Creb1 4 0.50 0.69 1.09
23 INT114536 Regulation of Negative_regulation of Creb1 1 0.45 0 0.72
24 INT271162 Positive_regulation of Regulation of Creb1 1 0.20 0.3 0.67
25 INT121868 Regulation of Localization of Creb1 1 0.23 0 0.66
26 INT303595 Negative_regulation of Localization of Creb1 1 0.19 0.86 0.57
27 INT207194 Regulation of Regulation of Creb1 2 0.45 1.09 0.46
28 INT124256 Positive_regulation of Binding of Creb1 2 0.40 1.27 0.39
29 INT274924 Positive_regulation of Protein_catabolism of Creb1 1 0.30 0 0.39
30 INT124253 Negative_regulation of Binding of Creb1 3 0.42 0.75 0.32
31 INT273921 Regulation of Binding of Creb1 2 0.35 0.28 0.16
32 INT207192 Negative_regulation of Transcription of Creb1 1 0.43 0.58 0.11
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