G:1312

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Official Symbol COMT
Aliases none
EntrezGene 1312
UniProt Coming Soon
Unique Molecular Interactions 11
Total Molecular Interactions 14
Total Single Events 245
Unique Interaction Partners 10

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to COMT. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to COMT. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to COMT. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
2 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
3 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
4 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88
5 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
6 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74
7 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
8 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21
9 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
10 INT195423 COMT Negative_regulation of GBE1 1 0.00 0.22 0.19
11 INT202253 Binding of COMT and TCN1 1 0.16 0 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1312. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1312. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
2 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05
3 INT135629 Binding of COMT 33 0.48 16.68 19.37
4 INT17619 Regulation of COMT 12 0.45 8.46 12.22
5 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28
6 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89
7 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08
8 INT194289 Transcription of COMT 3 0.72 3.56 2.72
9 INT202257 Localization of COMT 7 0.75 2.13 2.65
10 INT265662 Negative_regulation of Binding of COMT 4 0.37 1.29 2.42
11 INT136962 Protein_catabolism of COMT 4 0.89 1.12 2.14
12 INT265659 Positive_regulation of Negative_regulation of COMT 1 0.43 0.78 1.57
13 INT246088 Negative_regulation of Negative_regulation of COMT 2 0.37 2.01 1
14 INT265663 Positive_regulation of Gene_expression of COMT 2 0.50 0.26 0.79
15 INT136963 Regulation of Protein_catabolism of COMT 1 0.24 0.49 0.72
16 INT265655 Regulation of Positive_regulation of COMT 1 0.39 0.38 0.49
17 INT266128 Positive_regulation of Transcription of COMT 1 0.44 0.35 0.41
18 INT266123 Negative_regulation of Transcription of COMT 1 0.59 0.65 0.3
19 INT266127 Regulation of Binding of COMT 1 0.39 0.54 0.27
20 INT266124 Positive_regulation of Binding of COMT 1 0.44 0 0.23
21 INT266122 Regulation of Localization of COMT 1 0.39 0 0.21
22 INT266125 Regulation of Transcription of COMT 1 0.24 0.88 0.08
23 INT292012 Positive_regulation of Localization of COMT 1 0.44 0.13 0
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