G:13489

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Official Symbol Drd2
Aliases D2R, Drd-2
EntrezGene 13489
UniProt Coming Soon
Unique Molecular Interactions 39
Total Molecular Interactions 52
Total Single Events 425
Unique Interaction Partners 26

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Drd2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Drd2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Drd2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
2 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
3 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
4 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
5 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
6 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
7 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
8 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87
9 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
10 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
11 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76
12 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75
13 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
14 INT209131 Binding of Bcl2a1a and Drd2 1 0.22 0.45 0.62
15 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
16 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
17 INT165045 Drd2 Regulation of Cpe 1 0.07 0 0.52
18 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
19 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52
20 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
21 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
22 INT36009 Binding of Drd2 and Prl 1 0.01 1.05 0.42
23 INT334835 Negative_regulation of Binding of Drd2 and Ncs1 1 0.04 0.56 0.38
24 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
25 INT334836 Ncs1 Regulation of Drd2 1 0.02 0.48 0.33
26 INT109894 Drd2 Positive_regulation of FOS 1 0.01 0 0.33
27 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28
28 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28
29 INT69254 Drd2 Regulation of Gene_expression of Pomc 1 0.01 0 0.2
30 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13
31 INT227957 Chrm4 Regulation of Localization of Drd2 1 0.19 0.38 0.13
32 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13
33 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13
34 INT227959 Drd2 Regulation of Chrm4 1 0.08 0.38 0.13
35 INT8046 SORT1 Negative_regulation of Drd2 1 0.00 0 0.09
36 INT244092 Binding of C2 and Drd2 1 0.01 0.06 0.07
37 INT327711 Binding of Drd2 and Uts2r 1 0.07 0.41 0.04
38 INT69257 Drd2 Regulation of Gene_expression of Cpe 1 0.06 0 0
39 INT69256 Drd2 Regulation of Regulation of Pomc 1 0.29 0 0
40 INT69255 Drd2 Regulation of Transcription of Pomc 1 0.29 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 13489. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 13489. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
2 INT13501 Binding of Drd2 65 0.48 23.76 35.6
3 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
4 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
5 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
6 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
7 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
8 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
9 INT86772 Localization of Drd2 14 0.80 1.93 6.17
10 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
11 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
12 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
13 INT102209 Negative_regulation of Gene_expression of Drd2 5 0.59 0.46 3.17
14 INT75062 Regulation of Transcription of Drd2 1 0.51 0 1.41
15 INT11086 Regulation of Positive_regulation of Drd2 2 0.45 1.22 0.84
16 INT184840 Positive_regulation of Transcription of Drd2 2 0.35 1.03 0.65
17 INT66984 Regulation of Binding of Drd2 1 0.60 0 0.47
18 INT337102 Protein_catabolism of Drd2 1 0.88 0 0
19 INT263506 Regulation of Regulation of Drd2 1 0.26 0.34 0
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