G:13614

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Official Symbol Edn1
Aliases ET-1, preproET
EntrezGene 13614
UniProt Coming Soon
Unique Molecular Interactions 44
Total Molecular Interactions 60
Total Single Events 354
Unique Interaction Partners 30

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Edn1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Edn1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Edn1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
3 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
4 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
5 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
6 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
7 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
8 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
9 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
10 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
11 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
12 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
13 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
14 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
15 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
16 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
17 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
18 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
19 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
20 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
21 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
22 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
23 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
24 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
25 INT50499 Edn1 Positive_regulation of Pla2g1b Positive_regulation of Pla2g1b 1 0.00 0.07 0.15
26 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
27 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
28 INT50498 Edn1 Regulation of Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
29 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
30 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
31 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
32 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
33 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
34 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
35 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
36 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
37 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03
38 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03
39 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
40 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
41 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0
42 INT192910 Edn1 Regulation of Col4a1 1 0.16 0.49 0
43 INT192911 Edn1 Positive_regulation of Positive_regulation of Col4a1 1 0.24 0.13 0
44 INT192909 Regulation of Edn1 Regulation of Col4a1 1 0.16 0.49 0
45 INT213008 Hdl1 Positive_regulation of Gene_expression of Edn1 1 0.10 0.85 0
46 INT199312 Edn1 Negative_regulation of VEGFA 1 0.01 0.76 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 13614. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 13614. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
2 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
3 INT6361 Localization of Edn1 30 0.81 19.09 9.7
4 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
5 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
6 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
7 INT53374 Binding of Edn1 17 0.43 11.66 2.98
8 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
9 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
10 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
11 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
12 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
13 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
14 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
15 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
16 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
17 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
18 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
19 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
20 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
21 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
22 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
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