G:1385

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Official Symbol CREB1
Aliases CREB, MGC9284
EntrezGene 1385
UniProt Coming Soon
Unique Molecular Interactions 41
Total Molecular Interactions 48
Total Single Events 260
Unique Interaction Partners 28

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CREB1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CREB1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CREB1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
2 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
3 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
4 INT194714 CREB1 Regulation of Gene_expression of IK 1 0.00 0.07 0.25
5 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
6 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
7 INT255940 Elk1 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
8 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
9 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
10 INT255947 CREB1 Regulation of Transcription of Elk1 1 0.03 0.12 0.22
11 INT255943 Elk1 Regulation of Binding of CREB1 1 0.03 0.12 0.22
12 INT255938 CREB1 Regulation of Binding of Elk1 1 0.03 0.12 0.22
13 INT194807 MAPK1 Positive_regulation of Binding of CREB1 and Nfatc1 1 0.01 0.08 0.19
14 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
15 INT182929 Binding of CREB1 and KCNIP3 1 0.18 0.37 0.19
16 INT194805 MAPK1 Positive_regulation of Binding of CREB1 and Crebbp 1 0.02 0.08 0.19
17 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16
18 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
19 INT117912 CREB1 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.89 0.13
20 INT182958 Binding of CA2 and CREB1 1 0.04 0.25 0.13
21 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
22 INT54544 CREB1 Regulation of PENK 1 0.59 0 0.12
23 INT54545 Binding of CREB1 and PENK 1 0.35 0 0.12
24 INT194671 MAPKAPK2 Positive_regulation of CREB1 1 0.06 0.05 0.1
25 INT194825 Camk4 Positive_regulation of CREB1 1 0.01 0 0.1
26 INT194721 MAPK1 Positive_regulation of CREB1 1 0.08 0.05 0.1
27 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
28 INT194668 CREB1 Negative_regulation of Transcription of IK 1 0.00 0.07 0.08
29 INT275102 Prkcg Regulation of CREB1 1 0.01 0 0.06
30 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04
31 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04
32 INT185938 Phosphorylation of Prkaca Positive_regulation of CREB1 1 0.04 0.07 0.04
33 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03
34 INT333635 Positive_regulation of Tlr4 Positive_regulation of Transcription of CREB1 1 0.08 0 0.03
35 INT133489 CREB1 Positive_regulation of Csnk2b 1 0.08 0.42 0.03
36 INT333640 Tlr4 Positive_regulation of Transcription of CREB1 1 0.08 0 0.03
37 INT133482 CREB1 Positive_regulation of KCNMA1 1 0.01 0.43 0.03
38 INT333564 CREB1 Regulation of Transcription of JUN 1 0.02 0 0.03
39 INT133491 CREB1 Positive_regulation of Phosphorylation of Csnk2b 1 0.08 0.42 0.03
40 INT6676 Binding of Edn1 and Regulation of Gene_expression of CREB1 1 0.04 0.15 0
41 INT189012 Binding of CREB1 and Pp 1 0.00 0.17 0
42 INT194675 MAPK14 Positive_regulation of CREB1 1 0.07 0.33 0
43 INT194684 MAPK14 Positive_regulation of Transcription of CREB1 1 0.07 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1385. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1385. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
2 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
3 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
4 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
5 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
6 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
7 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
8 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
9 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
10 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
11 INT115494 Negative_regulation of Positive_regulation of CREB1 2 0.05 1.25 0.83
12 INT54546 Binding of CREB1 9 0.41 3.44 0.72
13 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61
14 INT116134 Positive_regulation of Positive_regulation of CREB1 2 0.28 0.59 0.45
15 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45
16 INT229206 Regulation of Positive_regulation of CREB1 2 0.11 0.25 0.25
17 INT98920 Localization of CREB1 4 0.52 1.77 0.1
18 INT69911 Negative_regulation of Binding of CREB1 1 0.48 0 0.1
19 INT194802 Negative_regulation of Gene_expression of CREB1 1 0.14 0.07 0.08
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