G:13866

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Official Symbol Erbb2
Aliases Neu, HER2, HER-2, c-neu, Erbb-2, c-erbB2, mKIAA3023
EntrezGene 13866
UniProt Coming Soon
Unique Molecular Interactions 16
Total Molecular Interactions 16
Total Single Events 259
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Erbb2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Erbb2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Erbb2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
2 INT144434 Gene_expression of Erbb2 Positive_regulation of ras 1 0.16 0.6 0.28
3 INT144433 Gene_expression of Erbb2 Positive_regulation of Positive_regulation of Mapk3 1 0.41 0.56 0.21
4 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
5 INT315163 Erbb2 Negative_regulation of Akt1 1 0.17 0.83 0
6 INT315161 Egfr Negative_regulation of Erbb2 1 0.36 0.83 0
7 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0
8 INT191099 Erbb2 Positive_regulation of Shc1 1 0.08 1.95 0
9 INT293493 Hsp90aa1 Regulation of Gene_expression of Erbb2 1 0.38 0.1 0
10 INT315166 Erbb2 Negative_regulation of Egfr 1 0.36 0.83 0
11 INT225266 Erbb2 Positive_regulation of Gene_expression of VEGFA 1 0.04 0.79 0
12 INT160861 Erbb2 Regulation of EGF 1 0.49 0.73 0
13 INT315168 Erbb2 Negative_regulation of Mapk3 1 0.03 0.83 0
14 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0
15 INT232558 Binding of Erbb2 and Esr1 1 0.24 0.59 0
16 INT93173 Ttf1 Positive_regulation of Erbb2 1 0.05 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 13866. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 13866. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
2 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
3 INT293487 Regulation of Gene_expression of Erbb2 4 0.61 3.4 1.06
4 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84
5 INT202196 Transcription of Erbb2 3 0.69 3.87 0.51
6 INT199559 Binding of Erbb2 5 0.36 4.23 0.36
7 INT181756 Positive_regulation of Erbb2 6 0.46 4.12 0.28
8 INT178191 Regulation of Erbb2 7 0.36 4.11 0.24
9 INT153075 Phosphorylation of Erbb2 5 0.73 2.06 0.19
10 INT153074 Negative_regulation of Phosphorylation of Erbb2 3 0.52 1.41 0.19
11 INT153073 Positive_regulation of Phosphorylation of Erbb2 1 0.39 0.47 0.1
12 INT232550 Negative_regulation of Gene_expression of Erbb2 9 0.43 4.96 0.07
13 INT221674 Localization of Erbb2 2 0.38 1.28 0.07
14 INT232554 Negative_regulation of Transcription of Erbb2 1 0.42 1.16 0
15 INT293491 Protein_catabolism of Erbb2 1 0.87 1.06 0
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