G:1392

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Official Symbol CRH
Aliases CRF
EntrezGene 1392
UniProt Coming Soon
Unique Molecular Interactions 57
Total Molecular Interactions 85
Total Single Events 706
Unique Interaction Partners 34

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CRH. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CRH. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CRH. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
2 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
3 INT34310 CRH Positive_regulation of POMC 3 0.42 0.62 2.21
4 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
5 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
6 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
7 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
8 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
9 INT18247 Binding of CRH and GNRH1 1 0.51 1.57 0.95
10 INT5451 CRH Regulation of POMC 2 0.28 0.39 0.85
11 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85
12 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81
13 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74
14 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
15 INT34311 Regulation of CRH Positive_regulation of POMC 1 0.24 0 0.59
16 INT61505 ABAT Negative_regulation of Localization of CRH 1 0.09 0 0.57
17 INT55872 Binding of ADRA1D and CRH 1 0.26 0 0.54
18 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
19 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 0.25 0 0.42
20 INT105771 CRH Negative_regulation of Localization of GNRH1 1 0.35 0.56 0.39
21 INT37249 CRH Positive_regulation of PPY 1 0.04 0.34 0.39
22 INT260893 CRH Positive_regulation of Gene_expression of IL8 1 0.28 0.05 0.31
23 INT111813 CREM Regulation of Regulation of CRH 1 0.12 0 0.3
24 INT107747 CRH Negative_regulation of HSD17B1 1 0.40 0.41 0.3
25 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3
26 INT35080 CRH Negative_regulation of Localization of FSHR 1 0.03 0 0.29
27 INT35079 CRH Negative_regulation of Localization of PLOD1 1 0.06 0 0.29
28 INT264782 Binding of CRH and CRHR1 1 0.02 0.06 0.28
29 INT31508 FEM1B Positive_regulation of Gene_expression of CRH 1 0.54 0 0.28
30 INT31505 CRH Positive_regulation of Gene_expression of FEM1B 1 0.54 0 0.28
31 INT180194 CRH Positive_regulation of CRHR2 1 0.02 0.24 0.27
32 INT180195 CRH Regulation of CRHR2 1 0.01 0.24 0.27
33 INT139271 Binding of CRH and POMC 1 0.35 1.1 0.22
34 INT100084 Binding of CRH and CRHR2 1 0.32 1.11 0.19
35 INT153322 CRH Positive_regulation of Positive_regulation of CRHR1 1 0.31 0.12 0.19
36 INT25495 AVP Positive_regulation of CRH 1 0.14 0 0.19
37 INT297393 TRIM6-TRIM34 Regulation of CRH 1 0.01 1.42 0.19
38 INT25497 AVP Positive_regulation of Localization of CRH 1 0.14 0 0.19
39 INT34346 CRH Regulation of DBI 1 0.01 0.25 0.17
40 INT107750 CRH Regulation of Transcription of HSD17B1 1 0.19 0.21 0.17
41 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16
42 INT57500 CREM Positive_regulation of Regulation of CRH 1 0.39 0 0.14
43 INT12830 Regulation of CRH Regulation of PENK 1 0.10 0.41 0.12
44 INT12828 CRH Regulation of PENK 1 0.10 0.41 0.12
45 INT198620 CRH Negative_regulation of GH1 1 0.05 0.47 0.05
46 INT198619 CRH Negative_regulation of TRH 1 0.18 0.47 0.05
47 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05
48 INT198618 CRH Negative_regulation of Localization of SST 1 0.07 0.53 0.05
49 INT247080 Binding of CRH and CRHBP 1 0.11 0.2 0.03
50 INT247077 CRHBP Regulation of Binding of CRH and CRHBP 1 0.06 0.2 0.03
51 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03
52 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0
53 INT121541 Positive_regulation of Binding of CRH and CCL7 1 0.09 0.07 0
54 INT144261 CRH Positive_regulation of SEMA6A 1 0.56 0 0
55 INT121542 Binding of CRH and CCL7 1 0.07 0.07 0
56 INT111768 IL2 Positive_regulation of Localization of CRH 1 0.02 0 0
57 INT233400 COPD Regulation of CRH 1 0.11 1.67 0
58 INT51878 CCBE1 Regulation of CRH 1 0.01 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1392. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1392. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5454 Localization of CRH 124 0.79 79.18 41.53
2 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74
3 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12
4 INT5452 Regulation of CRH 56 0.62 15.32 12.42
5 INT11288 Negative_regulation of CRH 44 0.00 16.69 12.37
6 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79
7 INT5455 Negative_regulation of Localization of CRH 16 0.49 7.31 6.41
8 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7
9 INT7559 Transcription of CRH 37 0.69 4.84 3.61
10 INT25029 Positive_regulation of Positive_regulation of CRH 7 0.49 6.77 3.52
11 INT63534 Binding of CRH 23 0.47 6.84 3.43
12 INT23763 Regulation of Localization of CRH 6 0.48 0.22 3.04
13 INT12835 Negative_regulation of Positive_regulation of CRH 6 0.42 3.15 1.76
14 INT115963 Negative_regulation of Gene_expression of CRH 9 0.59 4.53 1.48
15 INT34312 Regulation of Gene_expression of CRH 6 0.46 1.97 1.48
16 INT97763 Negative_regulation of Binding of CRH 2 0.42 0 0.76
17 INT194127 Negative_regulation of Transcription of CRH 2 0.41 0.16 0.51
18 INT12833 Regulation of Regulation of CRH 2 0.27 1.32 0.44
19 INT7558 Regulation of Transcription of CRH 1 0.60 0.06 0.35
20 INT67420 Negative_regulation of Negative_regulation of CRH 2 0.43 0.81 0.28
21 INT28717 Regulation of Positive_regulation of CRH 2 0.29 1.4 0.24
22 INT12834 Positive_regulation of Transcription of CRH 3 0.67 1 0.2
23 INT264799 Regulation of Binding of CRH 1 0.04 0 0.11
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