G:1401

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Official Symbol CRP
Aliases PTX1, MGC88244, MGC149895
EntrezGene 1401
UniProt Coming Soon
Unique Molecular Interactions 95
Total Molecular Interactions 208
Total Single Events 2085
Unique Interaction Partners 70

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CRP. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CRP. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CRP. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
2 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
3 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2
4 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
5 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
6 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
7 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
8 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
9 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71
10 INT202037 Binding of CRP and URB1 1 0.01 1.26 0.68
11 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
12 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59
13 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
14 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
15 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51
16 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
17 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48
18 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47
19 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45
20 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43
21 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
22 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
23 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
24 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
25 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36
26 INT270789 CRP Negative_regulation of Gene_expression of TNF 1 0.34 0.87 0.36
27 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32
28 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
29 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
30 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28
31 INT194045 Binding of CRP and PM20D2 1 0.01 1.64 0.27
32 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26
33 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26
34 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26
35 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24
36 INT184404 CRP Regulation of Gene_expression of KRT20 1 0.02 1.21 0.24
37 INT194047 Negative_regulation of Binding of CRP and PM20D2 1 0.02 1.57 0.23
38 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21
39 INT228703 MPO Regulation of Positive_regulation of CRP 1 0.40 1.63 0.2
40 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2
41 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19
42 INT240625 Binding of CRP and Hdlcl1 1 0.01 2.56 0.19
43 INT139302 Binding of CRP and TLR4 1 0.38 1.18 0.19
44 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17
45 INT254392 Binding of CRP and GSN 1 0.12 0.33 0.16
46 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
47 INT140648 Binding of CRP and CCL11 1 0.14 0.88 0.13
48 INT266681 TRD@ Regulation of CRP 1 0.06 0.5 0.13
49 INT281267 Binding of CRP and TIMP1 1 0.06 0.82 0.13
50 INT255514 Binding of CRP and LAIR1 1 0.06 0 0.12
51 INT185162 Binding of CRP and Retn 1 0.13 2.8 0.12
52 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11
53 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1
54 INT192353 CRP Regulation of CP 1 0.20 2.46 0.1
55 INT279409 Binding of CRP and IGKV2-19 1 0.02 0.4 0.1
56 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1
57 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1
58 INT192352 CRP Regulation of HSPD1 1 0.15 2.46 0.1
59 INT10739 IL3 Positive_regulation of CRP 1 0.18 1.14 0.09
60 INT294711 CRP Regulation of CCL2 1 0.12 0 0.09
61 INT294712 CRP Regulation of IL6 1 0.41 0 0.09
62 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08
63 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08
64 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08
65 INT299493 IL6 Positive_regulation of CRP 1 0.55 0.16 0.08
66 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
67 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07
68 INT332305 Binding of CRP and Ccl2 1 0.15 0.86 0.06
69 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06
70 INT255512 Binding of COL5A2 and CRP 1 0.01 0 0.06
71 INT279406 Binding of CRP and MTRF1 1 0.02 0.23 0.05
72 INT170668 GOPC Regulation of CRP 1 0.07 0.32 0.04
73 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
74 INT279536 Binding of C1QC and CRP 1 0.01 0.59 0.04
75 INT319120 CRP Positive_regulation of Gene_expression of SERPINE1 1 0.70 0.54 0.04
76 INT313508 Binding of ALOX12 and CRP 1 0.06 0.44 0.03
77 INT278291 Binding of CRP and DBP 1 0.12 1.57 0.03
78 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03
79 INT278290 Binding of CRP and PADI4 1 0.11 1.2 0.03
80 INT192354 Binding of CRP and HSPD1 1 0.12 1.28 0
81 INT218260 Binding of CRP and HIST2H4A 1 0.03 1.93 0
82 INT308583 Binding of CRP and PLA2G7 1 0.28 1.23 0
83 INT265951 Clas4 Negative_regulation of CRP 1 0.01 0.57 0
84 INT353910 Binding of CRP and UROD 1 0.06 0.34 0
85 INT242034 Positive_regulation of Binding of CRP and CHDH 1 0.18 2.08 0
86 INT192356 Binding of CP and CRP 1 0.16 4.35 0
87 INT313499 Binding of ALOX5AP and CRP 1 0.07 0.45 0
88 INT218259 Binding of CRP and SEPT5 1 0.04 0.33 0
89 INT242022 Negative_regulation of Binding of CRP and CIMT 1 0.33 1.01 0
90 INT242040 Negative_regulation of CRP Regulation of CHDH 1 0.17 0.58 0
91 INT265952 Clas4 Regulation of Negative_regulation of CRP 1 0.01 0.57 0
92 INT242024 CRP Regulation of CIMT 1 0.24 0.44 0
93 INT242032 Binding of CRP and RS1 1 0.01 1.92 0
94 INT291623 Binding of CRP and CSTA 1 0.03 0.38 0
95 INT242036 CRP Regulation of CHDH 1 0.18 1.57 0
96 INT218258 Binding of CRP and HIST1H1B 1 0.05 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1401. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1401. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
2 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
3 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33
4 INT100861 Binding of CRP 179 0.48 175.2 26.45
5 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9
6 INT23257 Regulation of CRP 127 0.62 100.05 21.87
7 INT106745 Localization of CRP 65 0.81 66.44 15.21
8 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58
9 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61
10 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07
11 INT204124 Transcription of CRP 14 0.69 20.79 2.71
12 INT171576 Phosphorylation of CRP 6 0.80 5.55 1.22
13 INT184415 Regulation of Positive_regulation of CRP 3 0.43 4.32 0.77
14 INT279202 Positive_regulation of Localization of CRP 3 0.69 2.45 0.72
15 INT204123 Positive_regulation of Transcription of CRP 5 0.49 8.11 0.57
16 INT270790 Negative_regulation of Binding of CRP 5 0.42 2.9 0.55
17 INT231736 Regulation of Transcription of CRP 1 0.45 1.46 0.54
18 INT204119 Negative_regulation of Transcription of CRP 2 0.36 2.57 0.52
19 INT265901 Regulation of Localization of CRP 1 0.30 2 0.27
20 INT242028 Negative_regulation of Negative_regulation of CRP 3 0.43 2.39 0.24
21 INT194049 Positive_regulation of Binding of CRP 3 0.48 4.48 0.24
22 INT188242 Negative_regulation of Positive_regulation of CRP 4 0.23 3.94 0.22
23 INT329446 Positive_regulation of Phosphorylation of CRP 1 0.29 0.44 0.16
24 INT355774 Negative_regulation of Regulation of CRP 1 0.15 0.64 0.15
25 INT240125 Positive_regulation of Negative_regulation of CRP 2 0.37 1.04 0.14
26 INT153771 Negative_regulation of Localization of CRP 3 0.38 0.99 0.09
27 INT174491 Positive_regulation of Regulation of CRP 2 0.22 0.9 0.04
28 INT351620 Protein_catabolism of CRP 1 0.88 0 0.03
29 INT351621 Negative_regulation of Protein_catabolism of CRP 1 0.38 0 0.03
30 INT242027 Regulation of Regulation of CRP 1 0.27 0 0
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