G:142

From wiki-pain
Jump to: navigation, search
Official Symbol PARP1
Aliases PARP, PPOL, ADPRT, ADPRT1, PARP-1, ADPRT 1, pADPRT-1
EntrezGene 142
UniProt Coming Soon
Unique Molecular Interactions 15
Total Molecular Interactions 22
Total Single Events 281
Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PARP1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PARP1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PARP1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
2 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
3 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
4 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
5 INT81159 Binding of PARP1 and IgG-2a 1 0.00 1.02 0.21
6 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06
7 INT155915 PARP1 Positive_regulation of Binding of PARP1 and NFKB1 1 0.48 0 0
8 INT155920 PARP1 Regulation of Gene_expression of IL6 1 0.19 0.08 0
9 INT155926 PARP1 Regulation of Binding of NFKB1 1 0.24 0.16 0
10 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0
11 INT155916 PARP1 Positive_regulation of Gene_expression of TNF 1 0.42 0 0
12 INT155923 Negative_regulation of PARP1 Negative_regulation of Gene_expression of TNF 1 0.36 0.07 0
13 INT155919 Gene_expression of PARP1 Positive_regulation of Gene_expression of IL6 1 0.33 0 0
14 INT155922 PARP1 Positive_regulation of Binding of NFKB1 1 0.42 0.06 0
15 INT155924 Binding of PARP1 and NFKB1 1 0.34 0.23 0
16 INT155925 PARP1 Positive_regulation of NFKB1 1 0.42 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 142. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 142. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
2 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
3 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
4 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36
5 INT155091 Localization of PARP1 15 0.63 13.34 3.15
6 INT163833 Positive_regulation of Localization of PARP1 7 0.28 7.54 2.14
7 INT155928 Positive_regulation of Gene_expression of PARP1 13 0.68 6.54 2.1
8 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89
9 INT10993 Regulation of PARP1 4 0.26 2.04 1.89
10 INT153125 Negative_regulation of Protein_catabolism of PARP1 8 0.32 6.57 0.98
11 INT126585 Positive_regulation of Positive_regulation of PARP1 3 0.55 2.84 0.56
12 INT126586 Binding of PARP1 15 0.43 4.96 0.53
13 INT126584 Regulation of Positive_regulation of PARP1 1 0.24 0.78 0.49
14 INT10994 Regulation of Gene_expression of PARP1 1 0.01 0.2 0.38
15 INT154804 Negative_regulation of Positive_regulation of PARP1 2 0.34 3.88 0.33
16 INT352918 Transcription of PARP1 1 0.25 0.85 0.33
17 INT153126 Negative_regulation of Gene_expression of PARP1 3 0.19 2.09 0.29
18 INT169195 Negative_regulation of Localization of PARP1 1 0.27 0.99 0.26
19 INT325373 Negative_regulation of Binding of PARP1 1 0.31 0.98 0.15
20 INT257999 Phosphorylation of PARP1 1 0.12 0.28 0.05
21 INT155929 Positive_regulation of Negative_regulation of PARP1 2 0.49 1.02 0.04
22 INT236481 Negative_regulation of Negative_regulation of PARP1 1 0.15 0.95 0.04
23 INT155927 Positive_regulation of Binding of PARP1 2 0.49 0.32 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox