G:1493

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Official Symbol CTLA4
Aliases CD, GSE, GRD4, ICOS, CD152, CTLA-4, IDDM12, CELIAC3
EntrezGene 1493
UniProt Coming Soon
Unique Molecular Interactions 21
Total Molecular Interactions 84
Total Single Events 134
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CTLA4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CTLA4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CTLA4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
3 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
4 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
5 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7
6 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
7 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
8 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
9 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
10 INT157657 Binding of CTLA4 and FCGR1A 1 0.01 0.07 0.4
11 INT139068 Binding of CTLA4 and Cd80 1 0.00 0.33 0.33
12 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
13 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
14 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
15 INT333549 Binding of CTLA4 and PDCD1 1 0.36 1.2 0.27
16 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18
17 INT299763 Binding of APC and CTLA4 Positive_regulation of Ido1 1 0.11 0.31 0.14
18 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12
19 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
20 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09
21 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
22 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08
23 INT149120 Binding of CTLA4 and Cd28 1 0.03 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1493. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1493. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07
2 INT132278 Binding of CTLA4 32 0.39 18.69 8.17
3 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39
4 INT143083 Regulation of CTLA4 4 0.25 1.06 1.36
5 INT145986 Positive_regulation of CTLA4 8 0.56 2.66 0.82
6 INT264192 Positive_regulation of Gene_expression of CTLA4 6 0.43 2.06 0.45
7 INT160874 Protein_catabolism of CTLA4 1 0.88 0.56 0.39
8 INT294135 Positive_regulation of Positive_regulation of CTLA4 1 0.25 0.45 0.32
9 INT173956 Negative_regulation of Gene_expression of CTLA4 3 0.37 0.91 0.2
10 INT296068 Regulation of Gene_expression of CTLA4 1 0.16 0.22 0.2
11 INT277827 Localization of CTLA4 1 0.65 0 0.18
12 INT277819 Positive_regulation of Localization of CTLA4 1 0.43 0 0.18
13 INT149118 Regulation of Binding of CTLA4 1 0.33 0.32 0.07
14 INT276341 Transcription of CTLA4 1 0.30 1.04 0.07
15 INT283499 Negative_regulation of Positive_regulation of CTLA4 1 0.09 1.02 0.05
16 INT283512 Positive_regulation of Binding of CTLA4 1 0.11 1.03 0.03
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