G:15567

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Official Symbol Slc6a4
Aliases Htt, Sert, 5-HTT, AI323329, MGC124313, MGC124314
EntrezGene 15567
UniProt Coming Soon
Unique Molecular Interactions 34
Total Molecular Interactions 55
Total Single Events 328
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Slc6a4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Slc6a4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Slc6a4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
2 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
3 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
4 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
5 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
6 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
7 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
8 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
9 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
10 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
11 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
12 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
13 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
14 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
15 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
16 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
17 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
18 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
19 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
20 INT333304 Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.68 0.1 0.06
21 INT333297 Gtf3a Positive_regulation of Gene_expression of Slc6a4 1 0.01 0.1 0.06
22 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
23 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05
24 INT333301 Binding of Slc6a4 and Zic2 1 0.47 0 0.03
25 INT333307 Gene_expression of Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.45 0.05 0.03
26 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0
27 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0
28 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0
29 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0
30 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0
31 INT333306 Ephb1 Regulation of Gene_expression of Slc6a4 1 0.19 0.21 0
32 INT333295 Gtf3a Positive_regulation of Slc6a4 1 0.01 0 0
33 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0
34 INT333300 Positive_regulation of Zic2 Positive_regulation of Slc6a4 1 0.45 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 15567. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 15567. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
2 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
3 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
4 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
5 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
6 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
7 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
8 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
9 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
10 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
11 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
12 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
13 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
14 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
15 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
16 INT286687 Phosphorylation of Slc6a4 1 0.46 0 0.58
17 INT286690 Positive_regulation of Phosphorylation of Slc6a4 1 0.28 0 0.58
18 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36
19 INT340198 Regulation of Transcription of Slc6a4 1 0.36 0.66 0.22
20 INT103022 Positive_regulation of Transcription of Slc6a4 2 0.44 0.52 0.21
21 INT332749 Positive_regulation of Binding of Slc6a4 1 0.23 0.19 0.07
22 INT333286 Negative_regulation of Positive_regulation of Slc6a4 1 0.50 0 0
23 INT333280 Regulation of Localization of Slc6a4 1 0.38 0.18 0
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