G:16000

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Official Symbol Igf1
Aliases Igf-1, Igf-I, C730016P09Rik
EntrezGene 16000
UniProt Coming Soon
Unique Molecular Interactions 65
Total Molecular Interactions 94
Total Single Events 812
Unique Interaction Partners 39

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Igf1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Igf1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Igf1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
3 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
4 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
5 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
6 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36
7 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36
8 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35
9 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
10 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23
11 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
12 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
13 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2
14 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2
15 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
16 INT175991 Binding of VEGFA and Igf1 1 0.04 0.57 0.17
17 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
18 INT225778 Igf1 Negative_regulation of Positive_regulation of Ppi-rs 1 0.01 0.82 0.14
19 INT65272 Igf1 Positive_regulation of Binding of Col7a1 1 0.42 0 0.14
20 INT65269 Igf1 Positive_regulation of Gene_expression of Lox 1 0.15 0 0.14
21 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
22 INT215034 Gh Regulation of Igf1 1 0.13 0.27 0.13
23 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
24 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
25 INT228453 Igf1 Positive_regulation of Prkca 2 0.12 1.17 0.12
26 INT228456 Igf1 Positive_regulation of Trpv1 1 0.24 0.97 0.12
27 INT308651 Binding of Igf1 and Ins1 1 0.02 0.22 0.11
28 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 0.14 0.55 0.11
29 INT175987 Igf1 Positive_regulation of Serpina1c 1 0.13 0.54 0.11
30 INT340555 Igf1 Positive_regulation of Mapk1 1 0.24 0.65 0.09
31 INT276141 Binding of Gh and Igf1 2 0.34 0.66 0.08
32 INT175984 Igf1 Regulation of Localization of Serpina1c 1 0.14 0.54 0.08
33 INT315987 Rhd Positive_regulation of Gene_expression of Igf1 1 0.10 0.47 0.07
34 INT142348 Igf1 Positive_regulation of Akt1 2 0.50 1.16 0.06
35 INT142346 Igf1 Positive_regulation of Mapk3 1 0.75 0.33 0.06
36 INT295130 Igf1 Regulation of Grxcr1 1 0.02 0.64 0.06
37 INT343481 Epo Positive_regulation of Igf1 1 0.15 0.31 0.06
38 INT142345 Negative_regulation of Igf1 Positive_regulation of Akt1 1 0.42 0.33 0.06
39 INT295128 Igf1 Regulation of Transcription of Pou1f1 1 0.16 0.64 0.06
40 INT250538 Igf1 Positive_regulation of Gh 1 0.24 0.05 0.06
41 INT142347 Negative_regulation of Igf1 Positive_regulation of Mapk3 1 0.46 0.33 0.06
42 INT335023 Fgf21 Positive_regulation of Gene_expression of Igf1 1 0.49 0.65 0.05
43 INT198358 GH1 Regulation of Igf1 1 0.00 0.09 0.05
44 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05
45 INT184083 Positive_regulation of Gh Positive_regulation of Igf1 1 0.09 0.7 0.04
46 INT184115 Igf1 Positive_regulation of Gene_expression of Socs2 1 0.16 0.62 0.04
47 INT295573 Igf1 Positive_regulation of Gene_expression of Mstn 1 0.19 0 0
48 INT201767 Igf1 Positive_regulation of PIK3CG 1 0.00 0.84 0
49 INT315984 Rhd Positive_regulation of Localization of Igf1 1 0.07 0.25 0
50 INT295868 Igf1 Positive_regulation of VEGFA 1 0.16 0.19 0
51 INT200211 Gh Positive_regulation of Localization of Igf1 1 0.38 2.05 0
52 INT295574 Binding of Igf1 and Mstn 1 0.16 0.08 0
53 INT284370 Igf1 Regulation of Gene_expression of VEGFA 1 0.37 0.05 0
54 INT295857 Igf1 Regulation of Localization of Srsf1 1 0.50 0 0
55 INT253007 Igf1 Regulation of Gene_expression of PTTG1 1 0.03 0.46 0
56 INT215206 Gh Positive_regulation of Transcription of Igf1 1 0.03 0 0
57 INT215209 Binding of Igf1 and Igfbp3 1 0.11 0 0
58 INT333845 Igf1 Positive_regulation of Gene_expression of Creb1 1 0.21 0.13 0
59 INT199369 DST Regulation of Igf1 1 0.02 0.8 0
60 INT162437 Binding of Igf1 and Igfals 1 0.10 1.45 0
61 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0
62 INT315985 Rhd Positive_regulation of Igf1 1 0.07 0.25 0
63 INT295127 Proc Regulation of Igf1 1 0.00 0.48 0
64 INT284369 Igf1 Regulation of VEGFA 1 0.27 0.05 0
65 INT269769 Gh Regulation of Gene_expression of Igf1 1 0.04 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16000. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16000. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
2 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
3 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
4 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
5 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
6 INT151032 Localization of Igf1 49 0.76 26.32 5.71
7 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
8 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
9 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
10 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
11 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
12 INT90491 Binding of Igf1 25 0.44 9.75 1.36
13 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
14 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
15 INT200198 Regulation of Localization of Igf1 6 0.58 4.51 0.34
16 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22
17 INT198357 Negative_regulation of Localization of Igf1 1 0.03 0.51 0.17
18 INT286068 Positive_regulation of Positive_regulation of Igf1 2 0.40 1.03 0.16
19 INT175970 Negative_regulation of Phosphorylation of Igf1 2 0.39 2.1 0.13
20 INT285632 Regulation of Binding of Igf1 1 0.37 0.55 0.13
21 INT175968 Phosphorylation of Igf1 6 0.74 2.54 0.1
22 INT175972 Regulation of Phosphorylation of Igf1 1 0.41 0.95 0.07
23 INT286067 Regulation of Regulation of Igf1 2 0.37 0.21 0.05
24 INT176243 Positive_regulation of Binding of Igf1 3 0.07 1.36 0
25 INT142343 Negative_regulation of Regulation of Igf1 2 0.41 0.35 0
26 INT216450 Regulation of Transcription of Igf1 1 0.26 0 0
27 INT295565 Positive_regulation of Phosphorylation of Igf1 1 0.19 0.17 0
28 INT269768 Negative_regulation of Negative_regulation of Igf1 1 0.08 0.96 0
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