G:16153

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Official Symbol Il10
Aliases CSIF, Il-10
EntrezGene 16153
UniProt Coming Soon
Unique Molecular Interactions 117
Total Molecular Interactions 140
Total Single Events 1367
Unique Interaction Partners 76

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il10. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il10. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il10. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
2 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
3 INT129215 RYBP Positive_regulation of Il10 1 0.01 1.24 0.98
4 INT129213 RYBP Positive_regulation of Gene_expression of Il10 1 0.01 1.04 0.94
5 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
6 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82
7 INT187232 Vip Positive_regulation of Gene_expression of Il10 1 0.16 0.95 0.81
8 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
9 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79
10 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
11 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77
12 INT209045 Il10 Positive_regulation of Csf2 1 0.03 0.37 0.72
13 INT209050 Il10 Positive_regulation of Elf1 1 0.10 0.37 0.72
14 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
15 INT209042 Il10 Positive_regulation of Cxcl1 1 0.07 0.37 0.72
16 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72
17 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
18 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
19 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63
20 INT95545 Ptgir Regulation of Gene_expression of Il10 1 0.04 0.97 0.63
21 INT276598 Il10 Positive_regulation of Gene_expression of Paf 1 0.29 0.49 0.6
22 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6
23 INT276597 Paf Positive_regulation of Il10 1 0.27 0.48 0.6
24 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
25 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
26 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58
27 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
28 INT237205 LGALS4 Positive_regulation of Localization of Il10 1 0.05 0.65 0.56
29 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55
30 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
31 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5
32 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
33 INT185074 Bpifa2 Positive_regulation of Il10 1 0.20 0.84 0.48
34 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
35 INT253075 Prok2 Negative_regulation of Gene_expression of Il10 1 0.24 0.24 0.45
36 INT297694 Positive_regulation of Binding of Il10 and Il13ra1 1 0.01 1.12 0.44
37 INT297696 Binding of Il10 and Il13ra1 1 0.00 1.12 0.43
38 INT233513 Pklr Negative_regulation of Localization of Il10 1 0.04 1.12 0.39
39 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39
40 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39
41 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
42 INT187818 Gene_expression of Il10 Positive_regulation of Gene_expression of Il4 1 0.09 0.69 0.35
43 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34
44 INT112021 Binding of Il10 and IgG2a 1 0.07 0.31 0.33
45 INT112023 Binding of Ifng and Il10 1 0.03 0.31 0.33
46 INT254218 Binding of Il10 and Il10rb 1 0.00 0.87 0.32
47 INT254226 Binding of Il10 and Il10ra 1 0.00 0.87 0.32
48 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32
49 INT204792 Tnbs1 Positive_regulation of Transcription of Il10 1 0.09 1.2 0.32
50 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31
51 INT76397 Il10 Negative_regulation of Ngf 1 0.44 0.45 0.3
52 INT76395 Il10 Negative_regulation of Gene_expression of Ngf 1 0.45 0.45 0.3
53 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29
54 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29
55 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28
56 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
57 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28
58 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27
59 INT251567 Il4 Negative_regulation of Gene_expression of Il10 1 0.01 0.96 0.27
60 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27
61 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26
62 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25
63 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24
64 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24
65 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
66 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
67 INT185065 Bpifa2 Positive_regulation of Gene_expression of Il10 1 0.20 0.22 0.18
68 INT316477 Stat3 Positive_regulation of Il10 1 0.39 0.35 0.18
69 INT331601 Il10 Regulation of IFN1@ 1 0.00 1.05 0.16
70 INT298055 Binding of IFN1@ and Il10 1 0.19 1.07 0.16
71 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
72 INT225989 Il10 Negative_regulation of Gene_expression of Hand1 1 0.11 0.68 0.13
73 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 0.01 0.44 0.13
74 INT228119 Il10 Negative_regulation of H2 1 0.07 0.38 0.13
75 INT333761 Il27 Positive_regulation of Il10 1 0.16 0.58 0.13
76 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13
77 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13
78 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13
79 INT253079 Prok2 Negative_regulation of Il10 1 0.24 0.31 0.13
80 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13
81 INT223751 Regulation of Tlr4 Positive_regulation of Il10 1 0.18 0 0.12
82 INT335993 Mmp8 Regulation of Il10 1 0.25 0.36 0.11
83 INT233384 Il10 Negative_regulation of Il12a 1 0.01 0.54 0.11
84 INT223750 Binding of Il10 and Tlr4 1 0.25 0.1 0.1
85 INT216943 Rtf1 Regulation of Localization of Il10 1 0.02 0.35 0.09
86 INT223755 Tlr4 Positive_regulation of Tlr4 Positive_regulation of Il10 1 0.22 0 0.09
87 INT223748 Tlr4 Positive_regulation of Il10 1 0.47 0 0.09
88 INT223749 Positive_regulation of Tlr4 Positive_regulation of Il10 1 0.34 0 0.09
89 INT297589 Binding of HAT1 and Il10 1 0.00 1.14 0.08
90 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 0.09 0.06 0.08
91 INT276987 Tlr2 Negative_regulation of Gene_expression of Il10 1 0.15 0.19 0.08
92 INT228747 Rae1 Regulation of Transcription of Il10 1 0.10 0.21 0.08
93 INT222869 Rpl13 Regulation of Il10 1 0.00 0.22 0.07
94 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06
95 INT228749 Il10 Regulation of Gene_expression of Il4 1 0.11 0.21 0.05
96 INT228743 Il10 Regulation of Gene_expression of Il13 1 0.14 0.21 0.05
97 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05
98 INT228750 Il10 Regulation of Gene_expression of Il5 1 0.12 0.21 0.05
99 INT314536 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of Il10 1 0.02 0.83 0.04
100 INT276951 Hspd1 Positive_regulation of Il10 1 0.05 0.75 0.04
101 INT276969 Tlr2 Positive_regulation of Il10 1 0.20 0.75 0.04
102 INT314538 Il10 Negative_regulation of Gene_expression of Ptger2 1 0.02 0.65 0.04
103 INT276990 Tlr2 Positive_regulation of Negative_regulation of Il10 1 0.20 0.75 0.04
104 INT314539 Ptger2 Positive_regulation of Gene_expression of Il10 1 0.04 0.83 0.04
105 INT276970 Hspd1 Positive_regulation of Gene_expression of Il10 1 0.10 0.69 0.03
106 INT126931 Slc8a2 Positive_regulation of Localization of Il10 1 0.12 0.08 0
107 INT228120 PDLIM7 Positive_regulation of Localization of Il10 1 0.51 1.37 0
108 INT228117 Chrm2 Positive_regulation of Positive_regulation of Il10 1 0.22 0.61 0
109 INT314537 Il10 Positive_regulation of Gene_expression of Itgam 1 0.21 1.23 0
110 INT313076 Tlr2 Positive_regulation of Gene_expression of Il10 1 0.02 0.14 0
111 INT228108 Il10 Negative_regulation of H2-Eb1 1 0.04 1.38 0
112 INT314535 Il10 Negative_regulation of Gene_expression of Gopc 1 0.05 0.23 0
113 INT276957 Il10 Positive_regulation of Localization of Stat3 1 0.14 0.16 0
114 INT228114 Chrm2 Positive_regulation of Gene_expression of Il10 1 0.22 0.61 0
115 INT156367 Ednra Positive_regulation of Gene_expression of Il10 1 0.01 0 0
116 INT276985 Il10 Positive_regulation of Phosphorylation of Stat3 1 0.14 0.16 0
117 INT126932 Slc8a2 Positive_regulation of Il10 1 0.09 0.06 0
118 INT276975 Il10 Positive_regulation of Gene_expression of Stat3 1 0.14 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16153. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16153. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
2 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
3 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
4 INT90792 Localization of Il10 144 0.80 87.88 30.03
5 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
6 INT79835 Regulation of Il10 28 0.61 21.22 11.29
7 INT71766 Transcription of Il10 31 0.69 24.66 10.78
8 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4
9 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37
10 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87
11 INT71767 Positive_regulation of Transcription of Il10 10 0.67 5.55 4.66
12 INT194846 Positive_regulation of Positive_regulation of Il10 9 0.57 5.07 3.71
13 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38
14 INT90791 Regulation of Localization of Il10 6 0.44 2.94 2.5
15 INT160241 Negative_regulation of Positive_regulation of Il10 6 0.39 6.33 1.92
16 INT223746 Binding of Il10 12 0.36 9.49 1.73
17 INT194854 Regulation of Positive_regulation of Il10 3 0.37 2.55 1.44
18 INT103755 Positive_regulation of Negative_regulation of Il10 3 0.49 2.64 1.4
19 INT107198 Negative_regulation of Transcription of Il10 3 0.38 4.19 1.14
20 INT103758 Negative_regulation of Negative_regulation of Il10 1 0.41 0 0.95
21 INT276928 Phosphorylation of Il10 4 0.58 1.74 0.49
22 INT275517 Positive_regulation of Binding of Il10 1 0.08 1.06 0.33
23 INT335988 Protein_catabolism of Il10 1 0.61 0.1 0.05
24 INT355686 Regulation of Transcription of Il10 1 0.12 0 0
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