G:16159

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Official Symbol Il12a
Aliases p35, Ll12a, Il-12a, IL-12p35, MGC151228, MGC151232
EntrezGene 16159
UniProt Coming Soon
Unique Molecular Interactions 63
Total Molecular Interactions 74
Total Single Events 743
Unique Interaction Partners 46

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il12a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il12a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il12a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
2 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
3 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
4 INT133177 Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
5 INT249656 tm Positive_regulation of Il12a 1 0.07 1.17 0.84
6 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
7 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
8 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7
9 INT250326 Binding of Il12a and Rpsa 1 0.09 0.93 0.59
10 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
11 INT217037 Binding of IRF6 and Il12a 1 0.01 0.08 0.5
12 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49
13 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48
14 INT222924 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il12a 1 0.01 0.59 0.45
15 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
16 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34
17 INT346915 Il12a Positive_regulation of Positive_regulation of IFN1@ 1 0.20 1.26 0.34
18 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31
19 INT93989 Rab8a Positive_regulation of Gene_expression of Il12a 1 0.10 0.48 0.3
20 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
21 INT164433 Il12a Positive_regulation of Il6 1 0.01 1.71 0.29
22 INT164434 Il12a Positive_regulation of Tnf 1 0.00 1.7 0.29
23 INT213808 Il12a Regulation of Gene_expression of Insrr 1 0.00 0.76 0.28
24 INT329369 Jun Regulation of Gene_expression of Il12a 1 0.00 1.48 0.27
25 INT254598 Il12a Positive_regulation of Gene_expression of IFNA1 1 0.11 0.4 0.25
26 INT289406 C3ar1 Positive_regulation of Gene_expression of Il12a 1 0.01 1.04 0.25
27 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24
28 INT186374 Il13 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23
29 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23
30 INT329306 Spp1 Positive_regulation of Il12a 1 0.08 1.19 0.23
31 INT240539 Il12a Positive_regulation of Stat3 1 0.11 0.75 0.22
32 INT240538 Il12a Positive_regulation of Phosphorylation of Stat4 1 0.11 0.76 0.22
33 INT260437 Positive_regulation of Tlr7 Positive_regulation of Positive_regulation of Il12a 1 0.03 0.27 0.21
34 INT240535 Il12a Positive_regulation of Tyk2 1 0.10 0.75 0.21
35 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
36 INT306746 Il12a Positive_regulation of TNF 1 0.24 0.5 0.21
37 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2
38 INT186353 Binding of Il12a and Il1 1 0.21 0.38 0.2
39 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19
40 INT266616 Il4 Positive_regulation of Il12a 1 0.01 0.4 0.17
41 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16
42 INT243632 Il12a Positive_regulation of Nfatc1 1 0.03 0.44 0.16
43 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15
44 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15
45 INT313914 Binding of Il12a and Il23r 1 0.14 0.44 0.13
46 INT247157 Tas2r129 Positive_regulation of Gene_expression of Il12a 1 0.00 1.23 0.13
47 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12
48 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12
49 INT338434 Binding of Il12a and TBX21 1 0.07 0.58 0.11
50 INT233384 Il10 Negative_regulation of Il12a 1 0.01 0.54 0.11
51 INT259852 Binding of Il12a and Retnlb 1 0.01 0.59 0.11
52 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
53 INT294679 GPI Positive_regulation of Gene_expression of Il12a 1 0.00 0.69 0.08
54 INT286298 Binding of Hand2 and Negative_regulation of Gene_expression of Il12a 1 0.07 0.3 0.07
55 INT247156 Tas2r129 Positive_regulation of Il12a 1 0.00 0.8 0.07
56 INT233502 Fzd5 Positive_regulation of Gene_expression of Il12a 1 0.04 0.33 0.07
57 INT243637 Il12a Positive_regulation of Transcription of Twist1 1 0.18 0.12 0.06
58 INT186382 TNF Regulation of Il12a 1 0.06 0.72 0.03
59 INT186386 Il12a Regulation of Gene_expression of TNF 1 0.06 0.66 0.03
60 INT186378 IFNA1 Positive_regulation of Il12a 1 0.03 0.76 0
61 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0
62 INT243623 Il12a Positive_regulation of Twist1 1 0.17 0 0
63 INT317857 Tlr4 Positive_regulation of Il12a 1 0.11 1.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16159. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16159. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
2 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
3 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
4 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87
5 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38
6 INT87239 Localization of Il12a 51 0.75 31.95 12.05
7 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4
8 INT106189 Regulation of Il12a 18 0.44 12.4 5.3
9 INT174160 Binding of Il12a 19 0.24 12.61 3.4
10 INT114181 Negative_regulation of Positive_regulation of Il12a 7 0.34 3.65 2.82
11 INT258781 Regulation of Regulation of Il12a 1 0.17 1.54 1.87
12 INT110950 Positive_regulation of Negative_regulation of Il12a 2 0.44 1.75 1.73
13 INT87241 Positive_regulation of Localization of Il12a 8 0.50 1.3 1.58
14 INT110028 Transcription of Il12a 6 0.49 1.48 1.51
15 INT110949 Negative_regulation of Negative_regulation of Il12a 1 0.41 0 0.98
16 INT110027 Regulation of Localization of Il12a 3 0.41 0.6 0.85
17 INT240523 Phosphorylation of Il12a 2 0.29 1.32 0.7
18 INT237764 Regulation of Binding of Il12a 1 0.29 0.82 0.52
19 INT252282 Positive_regulation of Phosphorylation of Il12a 1 0.08 0.59 0.49
20 INT174157 Negative_regulation of Localization of Il12a 4 0.09 1.54 0.48
21 INT110022 Positive_regulation of Transcription of Il12a 2 0.43 0.13 0.45
22 INT186272 Positive_regulation of Positive_regulation of Il12a 7 0.26 4.45 0.36
23 INT237901 Protein_catabolism of Il12a 2 1.00 0.79 0.36
24 INT216975 Regulation of Negative_regulation of Il12a 1 0.16 0 0.14
25 INT306724 Negative_regulation of Transcription of Il12a 1 0.18 0.3 0.1
26 INT350811 Regulation of Transcription of Il12a 1 0.11 0.2 0.04
27 INT186281 Positive_regulation of Binding of Il12a 2 0.26 2.09 0
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