G:16171

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Official Symbol Il17a
Aliases Il17, Ctla8, IL-17, Ctla-8, IL-17A
EntrezGene 16171
UniProt Coming Soon
Unique Molecular Interactions 48
Total Molecular Interactions 57
Total Single Events 713
Unique Interaction Partners 30

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il17a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il17a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il17a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
2 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
3 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
4 INT209048 Il3 Positive_regulation of Il17a 1 0.03 0.38 0.73
5 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
6 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73
7 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
8 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
9 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72
10 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67
11 INT252290 Binding of Il17a and Positive_regulation of Gene_expression of Ccl20 1 0.06 0.54 0.66
12 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
13 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65
14 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54
15 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54
16 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54
17 INT163391 Il17a Positive_regulation of Gene_expression of Crp 1 0.02 0.6 0.51
18 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
19 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46
20 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
21 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42
22 INT250328 Binding of TNF and Il17a 1 0.02 0.5 0.42
23 INT239042 Il17a Negative_regulation of Gene_expression of Il6 1 0.03 0.82 0.42
24 INT346130 Il17a Positive_regulation of Gene_expression of TNFSF11 1 0.08 0.61 0.41
25 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39
26 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38
27 INT161517 Mpo Positive_regulation of Gene_expression of Il17a 1 0.22 1.42 0.36
28 INT252289 Il17a Positive_regulation of Gene_expression of Il1 1 0.02 0.75 0.34
29 INT252295 Il17a Positive_regulation of Gene_expression of TNF 1 0.03 0.75 0.34
30 INT254221 Binding of Il17a and Il17ra 1 0.00 0.18 0.26
31 INT254203 Binding of Il17a and Hrec 1 0.00 0.19 0.26
32 INT254196 Binding of Il17a and Il17rc 1 0.01 0.18 0.26
33 INT335821 MIR146A Regulation of Gene_expression of Il17a 1 0.05 0.75 0.24
34 INT186391 TNF Positive_regulation of Gene_expression of Il17a 1 0.03 0.38 0.22
35 INT186358 Il1 Positive_regulation of Gene_expression of Il17a 1 0.02 0.38 0.22
36 INT318994 Il17a Regulation of Il23a 1 0.00 1.38 0.22
37 INT316538 Lvs Positive_regulation of Gene_expression of Il17a 1 0.30 1.3 0.21
38 INT231622 Pax3 Positive_regulation of Il17a 1 0.03 1.01 0.19
39 INT184458 Il17a Positive_regulation of Transcription of Adamts1 1 0.05 0.87 0.18
40 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16
41 INT265212 Cd28 Negative_regulation of Gene_expression of Il17a 1 0.10 0 0.09
42 INT316539 Il17a Positive_regulation of Gene_expression of Lvs 1 0.22 1.02 0.08
43 INT265221 Binding of Cd28 and Positive_regulation of Gene_expression of Il17a 1 0.15 0.09 0.08
44 INT231621 Il6 Positive_regulation of Positive_regulation of Il17a 1 0.15 0.19 0.04
45 INT316496 Il17a Positive_regulation of VEGFA 1 0.11 0.65 0.03
46 INT160567 Il22 Positive_regulation of Il17a 1 0.01 0 0
47 INT160566 Positive_regulation of Il22 Positive_regulation of Il17a 1 0.01 0 0
48 INT265216 Cd28 Positive_regulation of Gene_expression of Il17a 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16171. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16171. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
2 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87
3 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82
4 INT160563 Localization of Il17a 34 0.74 26.53 10.24
5 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87
6 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43
7 INT115947 Regulation of Il17a 17 0.37 14.26 5.97
8 INT235510 Binding of Il17a 14 0.34 10.67 3.99
9 INT135408 Transcription of Il17a 8 0.64 10.7 3.39
10 INT239025 Regulation of Gene_expression of Il17a 9 0.42 7.18 2.09
11 INT184235 Positive_regulation of Localization of Il17a 4 0.35 4.26 1.89
12 INT236349 Positive_regulation of Positive_regulation of Il17a 7 0.46 5.96 1.67
13 INT204771 Negative_regulation of Transcription of Il17a 2 0.39 2.31 0.63
14 INT353931 Positive_regulation of Negative_regulation of Il17a 1 0.35 0.9 0.44
15 INT254261 Negative_regulation of Binding of Il17a 1 0.06 1 0.31
16 INT300537 Positive_regulation of Regulation of Il17a 1 0.39 1.74 0.29
17 INT204774 Positive_regulation of Transcription of Il17a 1 0.12 1.08 0.29
18 INT316529 Protein_catabolism of Il17a 2 0.82 2.21 0.26
19 INT220840 Phosphorylation of Il17a 2 0.75 1.24 0.23
20 INT237157 Negative_regulation of Localization of Il17a 1 0.14 0 0.22
21 INT316534 Regulation of Positive_regulation of Il17a 1 0.42 0.99 0.08
22 INT346125 Regulation of Binding of Il17a 1 0.35 0.22 0.07
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