G:16176

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Official Symbol Il1b
Aliases Il-1b, IL-1beta
EntrezGene 16176
UniProt Coming Soon
Unique Molecular Interactions 40
Total Molecular Interactions 53
Total Single Events 515
Unique Interaction Partners 25

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il1b. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il1b. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il1b. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
2 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
3 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
4 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
5 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
6 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
7 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
8 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
9 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
10 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
11 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
12 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
13 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
14 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
15 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83
16 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
17 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
18 INT161481 Slc7a12 Regulation of Gene_expression of Il1b 1 0.14 1.21 0.77
19 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
20 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74
21 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
22 INT58229 Il1b Regulation of Gene_expression of Fam166a 1 0.01 0 0.64
23 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
24 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
25 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
26 INT80752 Binding of Il1b and El4 1 0.49 0.08 0.54
27 INT80751 Negative_regulation of Binding of Il1b and El4 1 0.60 0.08 0.54
28 INT169400 Negative_regulation of IRF6 Positive_regulation of Gene_expression of Il1b 1 0.50 0.62 0.5
29 INT132729 Plat Positive_regulation of Il1b 1 0.09 0.76 0.41
30 INT165568 Tnf Regulation of Gene_expression of Il1b 1 0.41 1.26 0.41
31 INT109091 Tnf Positive_regulation of Localization of Il1b 1 0.56 1.08 0.36
32 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
33 INT189489 Il1b Positive_regulation of Localization of Darc 1 0.00 0.53 0.34
34 INT132732 Binding of Il1b and Il6 1 0.35 0.6 0.3
35 INT62549 Il1b Regulation of Icam1 1 0.13 0.39 0.25
36 INT62548 Il1b Regulation of Gene_expression of Icam1 1 0.22 0.39 0.25
37 INT302385 Il1b Positive_regulation of Nfib Positive_regulation of Gene_expression of Ccl2 1 0.00 1.48 0.09
38 INT204897 Tlr4 Positive_regulation of Il1b 1 0.21 0.09 0.09
39 INT302382 Il1b Positive_regulation of Gene_expression of Ccl2 1 0.00 1.39 0.09
40 INT302383 Il1b Positive_regulation of Nfib 1 0.00 1.42 0.09
41 INT204900 Tlr4 Negative_regulation of Il1b 1 0.19 0.09 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16176. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16176. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
2 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
3 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
4 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
5 INT48081 Localization of Il1b 46 0.80 21.59 22.4
6 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
7 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
8 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
9 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
10 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
11 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
12 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
13 INT80750 Binding of Il1b 11 0.47 7.97 5.95
14 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
15 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
16 INT116033 Negative_regulation of Transcription of Il1b 4 0.42 2.05 1.94
17 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26
18 INT83618 Regulation of Positive_regulation of Il1b 2 0.44 1.04 0.58
19 INT153878 Negative_regulation of Negative_regulation of Il1b 1 0.42 0.78 0.36
20 INT117736 Regulation of Localization of Il1b 1 0.02 1.33 0.18
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