G:16183

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Official Symbol Il2
Aliases Il-2
EntrezGene 16183
UniProt Coming Soon
Unique Molecular Interactions 55
Total Molecular Interactions 64
Total Single Events 726
Unique Interaction Partners 48

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
2 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
3 INT54501 beta-End6-31 Positive_regulation of Gene_expression of Il2 1 0.03 0 1.06
4 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
5 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
6 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
7 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
8 INT21535 Binding of Il2 and Il1f5 1 0.13 0 0.73
9 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
10 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73
11 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73
12 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73
13 INT151681 Il2 Negative_regulation of Art2a-ps 1 0.00 1.23 0.7
14 INT151678 Il2 Negative_regulation of Oas1b 1 0.13 1.23 0.7
15 INT54502 Pomc Positive_regulation of Gene_expression of Il2 1 0.16 0 0.68
16 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 0.10 0 0.66
17 INT72504 IgG Negative_regulation of Il2 1 0.37 0 0.65
18 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
19 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
20 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
21 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46
22 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46
23 INT70924 Binding of Il2 and Il4 1 0.07 0.34 0.36
24 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34
25 INT298993 Il2 Positive_regulation of Gene_expression of Il13 1 0.01 0.73 0.24
26 INT331087 Csf2 Positive_regulation of Gene_expression of Il2 1 0.00 0.22 0.24
27 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18
28 INT52790 D5Nam12 Regulation of Localization of Il2 1 0.01 0 0.18
29 INT211310 Trav6-3 Positive_regulation of Positive_regulation of Il2 1 0.02 0.2 0.15
30 INT302826 Negative_regulation of Binding of Il2 and Kit 1 0.01 1.28 0.14
31 INT302827 Binding of Il2 and Kit 1 0.01 1.27 0.14
32 INT315492 Hspg2 Negative_regulation of Gene_expression of Il2 1 0.06 0.14 0.14
33 INT252336 Il2 Positive_regulation of Akt1 1 0.01 0 0.13
34 INT215010 Myoz1 Positive_regulation of Gene_expression of Il2 1 0.05 0.13 0.13
35 INT299782 Cd28 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
36 INT299781 Cd80 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
37 INT253074 Prok2 Regulation of Gene_expression of Il2 1 0.09 0.15 0.1
38 INT315490 Hspg2 Negative_regulation of Il2 1 0.08 0 0.09
39 INT182897 Mak Positive_regulation of Gene_expression of Il2 1 0.38 0.09 0.07
40 INT192407 Col7a1 Positive_regulation of Gene_expression of Il2 1 0.01 0.09 0.07
41 INT215006 Myoz1 Regulation of Transcription of Il2 1 0.06 0.44 0.06
42 INT25399 Il2 Positive_regulation of Gene_expression of Csf2 1 0.41 0.07 0.05
43 INT182098 Binding of IL8 and Il2 1 0.00 0 0.04
44 INT299762 Binding of Cd28 and Positive_regulation of Gene_expression of Il2 1 0.03 0.07 0.04
45 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04
46 INT182099 Binding of TNF and Il2 1 0.01 0 0.04
47 INT265226 Binding of IFN1@ and Il2 1 0.07 0.19 0.04
48 INT182095 Binding of Il2 and Il6 1 0.01 0 0.04
49 INT120449 Pparg Positive_regulation of Negative_regulation of Il2 1 0.75 0 0.04
50 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
51 INT270660 Binding of Il2 and Idd3 1 0.29 0.92 0
52 INT146022 Oprl1 Positive_regulation of Negative_regulation of Il2 1 0.16 0.07 0
53 INT270662 Ctex Regulation of Il2 1 0.32 0.51 0
54 INT134560 Cpe Negative_regulation of Gene_expression of Il2 1 0.17 0 0
55 INT309837 Binding of Zfp366 and Trav6-3 Positive_regulation of Gene_expression of Il2 1 0.00 0.14 0
56 INT130902 Jag2 Regulation of Localization of Il2 1 0.01 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16183. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16183. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11807 Gene_expression of Il2 266 0.78 112 64.97
2 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
3 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
4 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96
5 INT20381 Localization of Il2 71 0.77 34.23 13.03
6 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22
7 INT25385 Positive_regulation of Localization of Il2 17 0.45 9.53 6.45
8 INT11805 Regulation of Gene_expression of Il2 19 0.62 6.62 5.2
9 INT59320 Transcription of Il2 32 0.69 6.39 4.95
10 INT11815 Regulation of Il2 16 0.59 4.81 2.83
11 INT25382 Binding of Il2 16 0.37 11.69 2.32
12 INT52789 Regulation of Localization of Il2 9 0.30 1.9 1.88
13 INT87236 Regulation of Negative_regulation of Il2 3 0.24 0.75 1.62
14 INT236091 Positive_regulation of Transcription of Il2 2 0.44 2.78 1.19
15 INT70817 Negative_regulation of Transcription of Il2 5 0.40 0.25 0.87
16 INT120447 Negative_regulation of Localization of Il2 9 0.56 1.74 0.86
17 INT70815 Negative_regulation of Positive_regulation of Il2 4 0.40 1.37 0.76
18 INT354977 Regulation of Positive_regulation of Il2 1 0.07 0.82 0.4
19 INT25388 Regulation of Binding of Il2 2 0.37 0.2 0.37
20 INT120448 Positive_regulation of Negative_regulation of Il2 1 0.45 0.19 0.19
21 INT11806 Positive_regulation of Positive_regulation of Il2 2 0.50 1.02 0.18
22 INT215001 Phosphorylation of Il2 1 0.41 0.05 0.14
23 INT120445 Negative_regulation of Negative_regulation of Il2 1 0.42 0.11 0.12
24 INT60073 Negative_regulation of Binding of Il2 2 0.42 1.03 0.09
25 INT315489 Regulation of Transcription of Il2 1 0.11 0 0.09
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