G:16189

From wiki-pain
Jump to: navigation, search
Official Symbol Il4
Aliases Il-4, BSF-1
EntrezGene 16189
UniProt Coming Soon
Unique Molecular Interactions 113
Total Molecular Interactions 132
Total Single Events 1110
Unique Interaction Partners 69

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Il4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Il4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Il4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
2 INT129214 RYBP Positive_regulation of Gene_expression of Il4 1 0.01 1.04 0.94
3 INT209037 Il4 Positive_regulation of Csf2 1 0.03 0.38 0.73
4 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
5 INT209058 Il4 Positive_regulation of Elf1 1 0.08 0.38 0.73
6 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73
7 INT209064 Il4 Positive_regulation of Cxcl1 1 0.05 0.38 0.73
8 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
9 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
10 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
11 INT325267 Il33 Positive_regulation of Gene_expression of Il4 1 0.16 1.59 0.69
12 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67
13 INT228497 Il4 Regulation of Ncoa5 1 0.01 1.24 0.57
14 INT184243 Mthfd1 Negative_regulation of Gene_expression of Il4 1 0.02 0.88 0.56
15 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
16 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51
17 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
18 INT184099 Il4 Positive_regulation of Stat4 1 0.13 0.28 0.49
19 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48
20 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48
21 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48
22 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48
23 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48
24 INT185067 Bpifa2 Positive_regulation of Il4 1 0.20 0.84 0.48
25 INT228739 Il4 Positive_regulation of Gene_expression of Ccl17 1 0.14 0.66 0.39
26 INT237417 Il1rn Regulation of Il4 1 0.02 0.96 0.39
27 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
28 INT254278 Binding of Il13 and Il4 1 0.02 0.74 0.38
29 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
30 INT70924 Binding of Il2 and Il4 1 0.07 0.34 0.36
31 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35
32 INT151677 Il4 Negative_regulation of Art2a-ps 1 0.00 0.61 0.35
33 INT151680 Il4 Negative_regulation of Oas1b 1 0.07 0.61 0.35
34 INT187818 Gene_expression of Il10 Positive_regulation of Gene_expression of Il4 1 0.09 0.69 0.35
35 INT54504 Pomc Positive_regulation of Gene_expression of Il4 1 0.13 0 0.34
36 INT294762 Il4 Regulation of Il13 2 0.09 0.92 0.32
37 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
38 INT297422 Lvs Positive_regulation of Gene_expression of Il4 1 0.04 1.2 0.3
39 INT228734 Rae1 Negative_regulation of Il4 1 0.08 0.68 0.29
40 INT213802 Il4 Regulation of Gene_expression of Insrr 1 0.00 0.76 0.29
41 INT278214 Ciita Regulation of Gene_expression of Il4 1 0.45 1.53 0.28
42 INT185078 Bpifa2 Regulation of Il4 1 0.08 0.4 0.28
43 INT87369 Il4 Positive_regulation of Penk 1 0.37 0 0.28
44 INT251567 Il4 Negative_regulation of Gene_expression of Il10 1 0.01 0.96 0.27
45 INT251581 Il4 Negative_regulation of Gene_expression of TNF 1 0.05 0.95 0.26
46 INT194810 Il4 Regulation of Positive_regulation of Nfatc1 1 0.02 0.15 0.25
47 INT346912 Il6 Positive_regulation of Gene_expression of Il4 1 0.07 0.62 0.24
48 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23
49 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23
50 INT67085 Penk Positive_regulation of Positive_regulation of Il4 1 0.06 0.08 0.23
51 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22
52 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22
53 INT284889 Gene_expression of Hand1 Positive_regulation of Gene_expression of Il4 1 0.21 0.4 0.18
54 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18
55 INT185077 Bpifa2 Positive_regulation of Gene_expression of Il4 1 0.15 0.22 0.18
56 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
57 INT266616 Il4 Positive_regulation of Il12a 1 0.01 0.4 0.17
58 INT315491 Hspg2 Negative_regulation of Gene_expression of Il4 1 0.04 0.22 0.17
59 INT261760 Il4 Positive_regulation of Phosphorylation of Stat6 1 0.50 0.48 0.16
60 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16
61 INT56596 Pomc Positive_regulation of Localization of Il4 1 0.20 0 0.15
62 INT184098 Binding of Il4 and Socs5 1 0.09 2.05 0.15
63 INT305846 Polk Positive_regulation of Gene_expression of Il4 1 0.13 0.24 0.15
64 INT334531 Nrp1 Negative_regulation of Gene_expression of Il4 1 0.08 0.48 0.14
65 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
66 INT334527 Sema3a Negative_regulation of Gene_expression of Il4 1 0.15 0.48 0.14
67 INT338422 Il4 Positive_regulation of Gtf3a 1 0.00 0.75 0.13
68 INT299262 Dep1 Positive_regulation of Gene_expression of Il4 1 0.03 0.82 0.13
69 INT194806 MAPK1 Positive_regulation of CD28 Positive_regulation of Il4 1 0.08 0.42 0.13
70 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13
71 INT194383 Il13 Positive_regulation of Gene_expression of Il4 1 0.00 1.75 0.13
72 INT194817 CD28 Positive_regulation of Il4 1 0.15 0.41 0.13
73 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
74 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13
75 INT347017 Cd86 Positive_regulation of Gene_expression of Il4 1 0.03 0 0.13
76 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
77 INT194814 Cd3e Positive_regulation of Gene_expression of Il4 1 0.05 0 0.12
78 INT253078 Prok2 Negative_regulation of Il4 1 0.23 0.08 0.1
79 INT265211 Il4 Negative_regulation of Il23a 1 0.01 0.07 0.1
80 INT155945 Il4 Negative_regulation of Gene_expression of Tgif2 1 0.06 0.15 0.1
81 INT201348 Binding of Il4 and Ik 1 0.01 0.67 0.09
82 INT344427 Il4 Regulation of Gene_expression of Siglec5 1 0.14 0.35 0.09
83 INT201349 Binding of Hand2 and Il4 1 0.17 0.67 0.09
84 INT311988 Il4 Positive_regulation of Mthfd1 1 0.08 0.28 0.08
85 INT278218 Hand1 Negative_regulation of Gene_expression of Il4 1 0.20 0.37 0.08
86 INT188361 Il4 Positive_regulation of Socs1 1 0.14 0.15 0.08
87 INT300655 Il4 Positive_regulation of Gene_expression of IFN1@ 1 0.22 0.82 0.08
88 INT194824 Il4 Positive_regulation of MAPK1 1 0.26 0 0.07
89 INT194834 Il4 Positive_regulation of Positive_regulation of MAPK1 1 0.18 0 0.06
90 INT194831 CD28 Positive_regulation of Gene_expression of Il4 1 0.15 0 0.06
91 INT228749 Il10 Regulation of Gene_expression of Il4 1 0.11 0.21 0.05
92 INT342042 Il4 Positive_regulation of Gene_expression of Il13 1 0.03 0 0.05
93 INT228763 Il4 Regulation of Gene_expression of Il13 1 0.15 0.21 0.05
94 INT228741 Il13 Regulation of Gene_expression of Il4 1 0.15 0.21 0.05
95 INT228756 Il5 Regulation of Gene_expression of Il4 1 0.13 0.21 0.05
96 INT228755 Il4 Regulation of Gene_expression of Il5 1 0.13 0.21 0.05
97 INT294765 Negative_regulation of Serpinb1-ps1 Positive_regulation of Il4 1 0.02 0.24 0.05
98 INT347016 Cd86 Regulation of Gene_expression of Il4 1 0.03 0.19 0.04
99 INT344430 Il4 Positive_regulation of Siglec5 1 0.23 0 0.04
100 INT344432 Il4 Positive_regulation of Gene_expression of Siglec5 1 0.32 0 0.04
101 INT186359 Stat6 Negative_regulation of Il4 1 0.06 0.78 0.04
102 INT186362 Il4 Negative_regulation of Transcription of Nos2 1 0.04 0.77 0.04
103 INT347009 Hand2 Regulation of Gene_expression of Il4 1 0.01 0.19 0.04
104 INT294759 Serpinb1-ps1 Positive_regulation of Il4 1 0.02 0.24 0.04
105 INT329973 Il4 Regulation of Gene_expression of Hspb8 1 0.00 0.68 0.03
106 INT186384 Il4 Negative_regulation of Gene_expression of IFNA1 1 0.01 0.48 0.03
107 INT347013 Il4 Regulation of Gene_expression of Cd86 1 0.02 0.07 0
108 INT270204 TNF Positive_regulation of Il4 1 0.01 0.53 0
109 INT305852 Polk Positive_regulation of Positive_regulation of Il4 1 0.13 0.08 0
110 INT304167 Il4 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.94 0
111 INT184093 Negative_regulation of Il4 Positive_regulation of Stat6 1 0.08 0.93 0
112 INT278207 Ciita Negative_regulation of Transcription of Il4 1 0.31 0.79 0
113 INT304174 Binding of IL1B and Il4 1 0.00 0.96 0
114 INT134561 Cpe Negative_regulation of Gene_expression of Il4 1 0.11 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16189. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16189. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
2 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
3 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
4 INT20379 Localization of Il4 85 0.73 51.22 20.55
5 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15
6 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42
7 INT79693 Regulation of Il4 30 0.51 21.96 8.6
8 INT51741 Regulation of Gene_expression of Il4 23 0.36 12.7 7.39
9 INT56594 Positive_regulation of Localization of Il4 17 0.48 10.17 4.15
10 INT92200 Negative_regulation of Localization of Il4 10 0.51 5.66 3.65
11 INT70919 Binding of Il4 19 0.36 6.58 3.59
12 INT97438 Transcription of Il4 17 0.67 9.17 3.4
13 INT97434 Positive_regulation of Positive_regulation of Il4 8 0.40 3.51 1.66
14 INT184241 Regulation of Localization of Il4 4 0.15 3.89 1.58
15 INT59319 Negative_regulation of Positive_regulation of Il4 6 0.57 3.48 1.17
16 INT186292 Positive_regulation of Negative_regulation of Il4 3 0.14 1.57 0.58
17 INT237765 Phosphorylation of Il4 3 0.33 1.28 0.51
18 INT97436 Positive_regulation of Transcription of Il4 3 0.51 1.8 0.38
19 INT335847 Positive_regulation of Phosphorylation of Il4 1 0.17 0.85 0.32
20 INT278194 Protein_catabolism of Il4 2 0.57 1.12 0.3
21 INT97435 Regulation of Transcription of Il4 2 0.45 0.32 0.18
22 INT278201 Negative_regulation of Transcription of Il4 1 0.27 0.28 0.08
23 INT338402 Regulation of Positive_regulation of Il4 1 0.19 0.53 0.07
24 INT298029 Positive_regulation of Regulation of Il4 1 0.15 0.39 0.04
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox