G:1636

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Official Symbol ACE
Aliases DCP, ICH, ACE1, DCP1, CD143, MVCD3, MGC26566
EntrezGene 1636
UniProt Coming Soon
Unique Molecular Interactions 30
Total Molecular Interactions 41
Total Single Events 784
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ACE. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ACE. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ACE. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
2 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
3 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
4 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
5 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
6 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
7 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
8 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
9 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
10 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
11 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
12 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
13 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
14 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
15 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17
16 INT75058 Negative_regulation of ACE Negative_regulation of HHIP 1 0.25 0.43 0.15
17 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
18 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
19 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
20 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12
21 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
22 INT281898 Binding of ANG and ACE Positive_regulation of KNG1 1 0.03 0.37 0.1
23 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
24 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
25 INT344945 Negative_regulation of ACE Positive_regulation of REN 1 0.23 0.64 0.09
26 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
27 INT200638 Binding of ACE and Agtr2 1 0.10 0.93 0.06
28 INT29521 Ace Positive_regulation of ACE 1 0.19 0 0.04
29 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04
30 INT200488 Binding of ACE and SUGT1 1 0.01 0.28 0
31 INT213584 Binding of AGTR2 and ACE 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1636. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1636. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
2 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
3 INT20664 Binding of ACE 60 0.48 35.27 9.16
4 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
5 INT42038 Localization of ACE 26 0.80 8.88 7.06
6 INT26477 Regulation of ACE 26 0.45 16.31 4.33
7 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
8 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93
9 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77
10 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37
11 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99
12 INT83995 Positive_regulation of Gene_expression of ACE 8 0.68 8.09 0.82
13 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7
14 INT72446 Negative_regulation of Binding of ACE 4 0.42 2.48 0.62
15 INT56045 Positive_regulation of Localization of ACE 3 0.69 1.38 0.6
16 INT181635 Positive_regulation of Protein_catabolism of ACE 1 0.15 0.41 0.38
17 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36
18 INT96863 Transcription of ACE 3 0.69 0.38 0.29
19 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29
20 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29
21 INT108414 Negative_regulation of Regulation of ACE 1 0.43 0.67 0.17
22 INT79993 Positive_regulation of Positive_regulation of ACE 2 0.49 0.78 0.1
23 INT270742 Negative_regulation of Phosphorylation of ACE 1 0.40 0.65 0
24 INT270740 Phosphorylation of ACE 1 0.76 0.65 0
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