G:16367

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Official Symbol Irs1
Aliases G972R, IRS-1
EntrezGene 16367
UniProt Coming Soon
Unique Molecular Interactions 28
Total Molecular Interactions 43
Total Single Events 279
Unique Interaction Partners 16

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Irs1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Irs1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Irs1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT246841 Binding of Irs1 and Ppp1r13b 5 0.16 0.94 0.28
2 INT255736 Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.14 2.31 0.16
3 INT246843 Positive_regulation of Binding of Irs1 and Ppp1r13b 1 0.18 0.28 0.16
4 INT246844 Binding of Irs1 and Myl7 1 0.05 0.43 0.11
5 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08
6 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08
7 INT246846 Binding of PIK3CA and Irs1 1 0.39 0.14 0.08
8 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08
9 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08
10 INT246839 Binding of Irs1 and Gopc 1 0.16 0.15 0.08
11 INT246842 Binding of Ins1 and Irs1 1 0.16 0.63 0.06
12 INT240873 Ins1 Positive_regulation of Phosphorylation of Irs1 1 0.05 0 0.05
13 INT240893 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Irs1 1 0.08 0.36 0.04
14 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04
15 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04
16 INT246834 Phosphorylation of Irs1 Negative_regulation of Ins1 1 0.14 0.44 0.03
17 INT342358 Binding of Irs1 and Erap1 1 0.37 0 0
18 INT321722 Negative_regulation of Binding of Irs1 and Ppp1r13b 1 0.20 0.07 0
19 INT321715 Regulation of Binding of Irs1 and Ppp1r13b 1 0.15 0.05 0
20 INT240880 Mapk8 Positive_regulation of Protein_catabolism of Irs1 1 0.21 0.14 0
21 INT342360 Binding of H2-K1 and Irs1 1 0.10 0 0
22 INT240900 Negative_regulation of Ros1 Positive_regulation of Gene_expression of Irs1 1 0.08 0.13 0
23 INT323495 Ghrl Positive_regulation of Irs1 1 0.20 0.5 0
24 INT342361 Binding of Irs1 and Rdh9 1 0.38 0 0
25 INT342362 Binding of Irs1 and Rara 1 0.15 0 0
26 INT240901 Negative_regulation of Ros1 Negative_regulation of Phosphorylation of Irs1 1 0.07 0.15 0
27 INT321713 Ins1 Positive_regulation of Irs1 1 0.04 0.05 0
28 INT342357 Binding of Irs1 and Irf6 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16367. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16367. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
2 INT237322 Gene_expression of Irs1 52 0.77 21.07 2
3 INT230799 Positive_regulation of Phosphorylation of Irs1 28 0.69 11.17 1.63
4 INT240842 Positive_regulation of Gene_expression of Irs1 31 0.69 12 1.31
5 INT240849 Negative_regulation of Phosphorylation of Irs1 11 0.43 4.74 0.85
6 INT246832 Positive_regulation of Irs1 16 0.69 7.33 0.55
7 INT246828 Binding of Irs1 9 0.37 2.68 0.42
8 INT240830 Positive_regulation of Protein_catabolism of Irs1 2 0.69 0.82 0.26
9 INT246817 Positive_regulation of Binding of Irs1 1 0.50 0.37 0.23
10 INT240818 Protein_catabolism of Irs1 3 0.98 1 0.22
11 INT246824 Negative_regulation of Irs1 6 0.43 2.13 0.17
12 INT240841 Regulation of Gene_expression of Irs1 3 0.45 0.75 0.15
13 INT301563 Positive_regulation of Positive_regulation of Irs1 1 0.16 1.32 0.15
14 INT230807 Regulation of Phosphorylation of Irs1 3 0.45 1.59 0.13
15 INT246818 Negative_regulation of Gene_expression of Irs1 3 0.42 1.25 0.1
16 INT240850 Regulation of Irs1 2 0.47 0.64 0.09
17 INT246825 Regulation of Positive_regulation of Irs1 1 0.45 0.47 0.09
18 INT246819 Negative_regulation of Binding of Irs1 3 0.42 0.62 0.07
19 INT301556 Negative_regulation of Positive_regulation of Irs1 1 0.10 1.63 0.04
20 INT246829 Localization of Irs1 2 0.74 0.9 0
21 INT246826 Positive_regulation of Localization of Irs1 1 0.50 0.76 0
22 INT323089 Positive_regulation of Transcription of Irs1 1 0.44 0.26 0
23 INT323107 Transcription of Irs1 1 0.50 0.26 0
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