G:16409

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Official Symbol Itgam
Aliases CR3, CR3A, MAC1, Cd11b, Ly-40, Mac-1, Mac-1a, CD11b/CD18, F730045J24Rik
EntrezGene 16409
UniProt Coming Soon
Unique Molecular Interactions 24
Total Molecular Interactions 32
Total Single Events 517
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Itgam. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Itgam. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Itgam. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
2 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54
3 INT161009 Binding of Cpe and Itgam 1 0.03 0.53 0.37
4 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37
5 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37
6 INT161001 Itgam Regulation of Gfap 1 0.13 0.52 0.37
7 INT161002 Binding of Itgam and St13 1 0.11 0.52 0.37
8 INT161008 Itgam Regulation of St13 1 0.08 0.52 0.37
9 INT61266 Nfkb1 Regulation of Gene_expression of Itgam 1 0.23 0.65 0.32
10 INT224454 TNF Positive_regulation of Gene_expression of Itgam 1 0.27 0.35 0.22
11 INT224445 Il1 Positive_regulation of Gene_expression of Itgam 1 0.21 0.35 0.22
12 INT236362 Binding of Gfap and Itgam 1 0.23 2.31 0.2
13 INT314534 Ptger2 Regulation of Gene_expression of Itgam 1 0.02 1 0.17
14 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15
15 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15
16 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15
17 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1
18 INT253300 Itgam Positive_regulation of Gene_expression of Ptprc 1 0.19 0.11 0.09
19 INT254390 Binding of FCGR2A and Itgam 1 0.24 0.63 0.04
20 INT314537 Il10 Positive_regulation of Gene_expression of Itgam 1 0.21 1.23 0
21 INT281314 Positive_regulation of Stx2 Positive_regulation of Gene_expression of Itgam 1 0.08 0.21 0
22 INT344229 Itgam Regulation of Transcription of Tlr4 1 0.03 0.06 0
23 INT344220 Itgam Regulation of Transcription of Tlr2 1 0.03 0.06 0
24 INT191933 Itgam Positive_regulation of Cpox 1 0.07 0.36 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16409. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16409. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26
2 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3
3 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43
4 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01
5 INT61259 Negative_regulation of Itgam 16 0.47 11.11 3.27
6 INT171117 Binding of Itgam 35 0.36 14.87 2.76
7 INT61262 Negative_regulation of Positive_regulation of Itgam 5 0.57 4.25 1.95
8 INT94117 Regulation of Gene_expression of Itgam 13 0.36 5.9 1.87
9 INT210709 Regulation of Itgam 8 0.28 9.21 1.76
10 INT152885 Localization of Itgam 16 0.73 7.62 1.43
11 INT15171 Positive_regulation of Positive_regulation of Itgam 4 0.49 1.13 0.64
12 INT253299 Positive_regulation of Localization of Itgam 4 0.29 3.04 0.55
13 INT192858 Phosphorylation of Itgam 4 0.47 1.71 0.38
14 INT236352 Positive_regulation of Binding of Itgam 4 0.36 2.92 0.29
15 INT152888 Transcription of Itgam 4 0.44 1.29 0.25
16 INT355260 Positive_regulation of Phosphorylation of Itgam 1 0.09 1.03 0.18
17 INT191932 Negative_regulation of Binding of Itgam 1 0.17 0.48 0
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