G:16428

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Official Symbol Itk
Aliases Emt, Tsk, Tcsk
EntrezGene 16428
UniProt Coming Soon
Unique Molecular Interactions 12
Total Molecular Interactions 12
Total Single Events 71
Unique Interaction Partners 10

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Itk. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Itk. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Itk. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
2 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22
3 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
4 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07
5 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04
6 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04
7 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
8 INT324056 Binding of Itk and Furin 1 0.03 0.48 0
9 INT326727 Sox10 Regulation of Regulation of Itk 1 0.02 0.06 0
10 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0
11 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0
12 INT326726 Twist1 Regulation of Itk 1 0.02 0.84 0
13 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16428. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16428. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09
2 INT120075 Gene_expression of Itk 11 0.43 6.39 1.27
3 INT169706 Positive_regulation of Gene_expression of Itk 2 0.32 2.08 0.81
4 INT233845 Negative_regulation of Itk 7 0.18 4.81 0.22
5 INT285664 Regulation of Itk 3 0.05 1.66 0.07
6 INT331613 Regulation of Positive_regulation of Itk 1 0.02 0.87 0.06
7 INT307937 Negative_regulation of Positive_regulation of Itk 1 0.18 2.5 0.05
8 INT324054 Negative_regulation of Gene_expression of Itk 1 0.08 0.39 0
9 INT307933 Binding of Itk 1 0.15 0.71 0
10 INT326710 Regulation of Gene_expression of Itk 1 0.03 0.06 0
11 INT307934 Localization of Itk 1 0.36 2.65 0
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