G:16452

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Official Symbol Jak2
Aliases Fd17, C81284, AI504024
EntrezGene 16452
UniProt Coming Soon
Unique Molecular Interactions 19
Total Molecular Interactions 22
Total Single Events 147
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Jak2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Jak2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Jak2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
2 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
3 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
4 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
5 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
6 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
7 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
8 INT253580 Csnk2a2 Negative_regulation of Jak2 Negative_regulation of Positive_regulation of Akt1 1 0.05 0 0.04
9 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
10 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
11 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
12 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
13 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
14 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
15 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
16 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
17 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
18 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
19 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
20 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16452. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16452. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
2 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
3 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
4 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
5 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
6 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
7 INT184062 Binding of Jak2 5 0.37 3.13 0.47
8 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
9 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
10 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
11 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
12 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
13 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
14 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
15 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
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