G:16476

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Official Symbol Jun
Aliases AP-1, Junc, c-jun
EntrezGene 16476
UniProt Coming Soon
Unique Molecular Interactions 70
Total Molecular Interactions 117
Total Single Events 663
Unique Interaction Partners 45

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Jun. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Jun. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Jun. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
2 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
3 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
4 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
5 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
6 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
7 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
8 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
9 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
10 INT288168 Binding of Jun and Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.01 0.52 0.36
11 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35
12 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
13 INT288165 Binding of Jun and Ugcg 1 0.02 0.45 0.32
14 INT110471 Cpe Regulation of Binding of Atf2 and Jun 1 0.02 0 0.32
15 INT124261 Jun Regulation of Gene_expression of Cpox 1 0.13 0.44 0.32
16 INT110463 Binding of Jun and Gtf3a 1 0.04 0 0.32
17 INT124259 Negative_regulation of Plat Positive_regulation of Jun 4 0.11 1.74 0.31
18 INT110459 Binding of Atf2 and Jun 1 0.32 0 0.31
19 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29
20 INT329369 Jun Regulation of Gene_expression of Il12a 1 0.00 1.48 0.27
21 INT305334 Jun Positive_regulation of Gene_expression of Tcstv1 1 0.00 1.04 0.27
22 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27
23 INT214977 Binding of Jun and Sigmar1 1 0.01 0.27 0.24
24 INT319556 Positive_regulation of Jun Negative_regulation of Positive_regulation of gr 1 0.05 0.17 0.24
25 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24
26 INT319557 Jun Negative_regulation of gr 1 0.05 0.05 0.23
27 INT324868 Binding of Jun and Tlr4 1 0.02 1.54 0.22
28 INT324873 Binding of Jun and Tlr3 1 0.01 1.54 0.22
29 INT208942 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of Jun 1 0.10 0.42 0.2
30 INT342599 Binding of Fos and Jun 1 0.32 0.99 0.2
31 INT106526 jb Negative_regulation of Phosphorylation of Jun 1 0.02 0.14 0.19
32 INT247600 Tlr4 Positive_regulation of Jun 1 0.05 0.52 0.17
33 INT58180 Gtf3a Positive_regulation of Gene_expression of Jun 1 0.05 0.1 0.16
34 INT226507 Il1rl1 Positive_regulation of Gene_expression of Jun 1 0.13 0.2 0.15
35 INT295265 Jun Regulation of Gtf3a 1 0.00 0.34 0.15
36 INT226516 Il1rl1 Positive_regulation of Phosphorylation of Jun 1 0.02 0.19 0.14
37 INT329371 IL8 Negative_regulation of Jun 1 0.00 0.95 0.13
38 INT324869 Binding of Jun and Ticam1 1 0.01 0.76 0.11
39 INT280841 Jun Positive_regulation of Gene_expression of Crh 1 0.35 0.16 0.1
40 INT246081 Mcpt1 Regulation of Localization of Jun 1 0.20 0.52 0.08
41 INT259926 Tnfaip8 Positive_regulation of Jun 1 0.52 0.31 0.08
42 INT259930 Negative_regulation of Tnfaip8 Positive_regulation of Jun 1 0.48 0.31 0.08
43 INT89726 RYBP Positive_regulation of Jun 1 0.01 0.31 0.08
44 INT319683 Binding of Jun and Nfe2l2 1 0.05 0.26 0.07
45 INT340567 Jun Positive_regulation of Gene_expression of Ccnd1 1 0.05 0.27 0.07
46 INT259931 Plat Positive_regulation of Gene_expression of Jun 1 0.08 0.58 0.07
47 INT259933 Negative_regulation of Akt1 Negative_regulation of Gene_expression of Jun 1 0.01 0.31 0.07
48 INT280818 Jun Positive_regulation of Avp 1 0.06 0.23 0.06
49 INT280834 Negative_regulation of Jun Positive_regulation of Avp 1 0.05 0.23 0.06
50 INT259928 Binding of Jun and Plat 1 0.06 0.16 0.05
51 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
52 INT310820 Trav6-3 Positive_regulation of Phosphorylation of Jun 1 0.04 0.22 0.04
53 INT259927 Positive_regulation of Plat Positive_regulation of Jun 1 0.08 0.78 0.04
54 INT272728 Binding of Creb1 and Jun 1 0.00 0.09 0.04
55 INT342601 Proc Regulation of Jun 1 0.00 0.23 0.03
56 INT259925 Regulation of Plat Positive_regulation of Jun 1 0.05 0.11 0.03
57 INT199863 Gopc Negative_regulation of Jun 1 0.03 1.07 0
58 INT199858 Gopc Negative_regulation of Phosphorylation of Jun 1 0.03 1.08 0
59 INT259929 Negative_regulation of Akt1 Negative_regulation of Positive_regulation of Jun 1 0.01 0.39 0
60 INT319658 Jun Regulation of Gadd45gip1 1 0.07 0.13 0
61 INT182884 Jun Regulation of Phosphorylation of Mapk8 1 0.07 0.18 0
62 INT182885 Jun Regulation of Mapk8 1 0.07 0.18 0
63 INT225532 Ncoa6 Regulation of Jun 1 0.03 0.21 0
64 INT319694 Jun Regulation of Gadd45gip1 Negative_regulation of Gopc 1 0.02 0.13 0
65 INT225495 Zfp335 Positive_regulation of Transcription of Jun 1 0.01 0 0
66 INT225506 Binding of Jun and Rbm39 1 0.04 0 0
67 INT182887 Jun Regulation of Mapk1 1 0.04 0.18 0
68 INT225508 Ncoa6 Positive_regulation of Jun 1 0.13 0 0
69 INT307421 Positive_regulation of Jun Positive_regulation of Positive_regulation of TNF 1 0.01 1.03 0
70 INT225510 D0Nrs1 Positive_regulation of Transcription of Jun 1 0.01 0 0
71 INT259932 Rdh2 Positive_regulation of Jun 1 0.01 0 0
72 INT286417 Rbm39 Negative_regulation of Jun 1 0.00 0.16 0
73 INT199862 Mapk8 Negative_regulation of Jun 1 0.05 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 16476. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 16476. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
2 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
3 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
4 INT61264 Regulation of Jun 36 0.61 18.42 8.71
5 INT64815 Binding of Jun 49 0.48 21.47 8.59
6 INT64816 Transcription of Jun 31 0.69 16.01 7.64
7 INT10344 Localization of Jun 23 0.73 6.36 7.46
8 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
9 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
10 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
11 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
12 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
13 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
14 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
15 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6
16 INT59358 Regulation of Gene_expression of Jun 10 0.61 3.7 2.11
17 INT64818 Regulation of Binding of Jun 3 0.33 1.06 1.17
18 INT106523 Positive_regulation of Phosphorylation of Jun 7 0.45 3.1 0.74
19 INT124739 Negative_regulation of Binding of Jun 2 0.40 1.45 0.74
20 INT154019 Protein_catabolism of Jun 2 0.61 0.07 0.67
21 INT307186 Negative_regulation of Phosphorylation of Jun 4 0.10 2.91 0.61
22 INT183165 Negative_regulation of Localization of Jun 1 0.07 1.32 0.23
23 INT240051 Regulation of Regulation of Jun 2 0.26 1.25 0.18
24 INT307999 Positive_regulation of Localization of Jun 1 0.09 0.16 0.13
25 INT239153 Regulation of Phosphorylation of Jun 2 0.27 1.46 0.07
26 INT347634 Positive_regulation of Regulation of Jun 1 0.08 1.04 0.04
27 INT310812 Positive_regulation of Negative_regulation of Jun 1 0.11 0.16 0.03
28 INT127366 Regulation of Positive_regulation of Jun 2 0.45 0 0
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