G:18024

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Official Symbol Nfe2l2
Aliases Nrf2, AI194320
EntrezGene 18024
UniProt Coming Soon
Unique Molecular Interactions 56
Total Molecular Interactions 120
Total Single Events 398
Unique Interaction Partners 26

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Nfe2l2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Nfe2l2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Nfe2l2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
2 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52
3 INT118396 Nfe2l2 Positive_regulation of Gene_expression of Cars 1 0.05 0.26 0.47
4 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
5 INT147475 co Positive_regulation of Gene_expression of Nfe2l2 1 0.01 0.57 0.36
6 INT119548 Fos Regulation of Gene_expression of Nfe2l2 1 0.48 0.47 0.25
7 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22
8 INT319663 Binding of Nfe2l2 and Keap1 1 0.40 2.83 0.17
9 INT319680 Keap1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.36 0.93 0.17
10 INT295261 Binding of Hmox1 and Nfe2l2 1 0.17 0.49 0.13
11 INT295264 Positive_regulation of Binding of Hmox1 and Nfe2l2 1 0.25 0.5 0.13
12 INT167747 Negative_regulation of Nfkb1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.45 0.41 0.11
13 INT167745 Negative_regulation of Nfkb1 Negative_regulation of Nfe2l2 1 0.45 0.41 0.11
14 INT167746 Nfkb1 Positive_regulation of Gene_expression of Nfe2l2 1 0.53 0.45 0.09
15 INT319672 Nfe2l2 Regulation of Binding of Keap1 1 0.23 0.46 0.09
16 INT131598 Keap1 Negative_regulation of Nfe2l2 2 0.65 1.27 0.08
17 INT319683 Binding of Jun and Nfe2l2 1 0.05 0.26 0.07
18 INT295260 Positive_regulation of Nfe2l2 Positive_regulation of Gene_expression of Gclm 1 0.26 0.23 0.07
19 INT266902 Nfe2l2 Positive_regulation of Sod2 1 0.16 0.19 0.04
20 INT266901 Nfe2l2 Positive_regulation of Cat 1 0.10 0.19 0.04
21 INT266897 Nfe2l2 Positive_regulation of Sod1 1 0.11 0.19 0.04
22 INT262149 Binding of Nfe2l2 and Rare1 1 0.03 0.32 0.03
23 INT315269 Rela Regulation of Gene_expression of Nfe2l2 1 0.10 0.25 0.03
24 INT319686 Positive_regulation of Sfn Positive_regulation of Nfe2l2 1 0.18 0 0
25 INT319690 Gadd45gip1 Positive_regulation of Nfe2l2 1 0.45 0 0
26 INT319682 Binding of Nfe2l2 and Gadd45gip1 1 0.43 1.41 0
27 INT319657 Binding of Nfe2l2 and Gopc 1 0.10 0.17 0
28 INT315271 Eri1 Regulation of Nfe2l2 1 0.00 0.48 0
29 INT319667 Gadd45gip1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.53 0.06 0
30 INT315259 Binding of Nfe2l2 and Gcat 1 0.00 0.52 0
31 INT319668 Keap1 Regulation of Nfe2l2 1 0.52 0.84 0
32 INT319693 Gene_expression of Gadd45gip1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.39 0 0
33 INT319673 Gadd45gip1 Regulation of Transcription of Nfe2l2 1 0.41 0.13 0
34 INT315268 Gopc Positive_regulation of Binding of Nfe2l2 1 0.10 0.09 0
35 INT315262 Negative_regulation of Keap1 Negative_regulation of Gene_expression of Nfe2l2 1 0.30 0.48 0
36 INT317769 Binding of Nfe2l2 and Acly 1 0.22 0.08 0
37 INT319687 Gadd45gip1 Negative_regulation of Nfe2l2 1 0.39 0.66 0
38 INT315266 Rela Positive_regulation of Negative_regulation of Nfe2l2 1 0.11 0.63 0
39 INT317768 Nfe2l2 Regulation of Acly 1 0.38 0.25 0
40 INT169050 Nfe2l2 Regulation of Sult4a1 1 0.01 0.17 0
41 INT319666 Gadd45gip1 Regulation of Nfe2l2 1 0.55 2.23 0
42 INT169056 Nfe2l2 Regulation of SULT1A2 1 0.00 0.17 0
43 INT319670 Negative_regulation of Binding of Nfe2l2 and Keap1 1 0.36 0.44 0
44 INT319681 Gadd45gip1 Regulation of Positive_regulation of Nfe2l2 1 0.41 0 0
45 INT319671 Gadd45gip1 Regulation of Protein_catabolism of Nfe2l2 1 0.24 0.44 0
46 INT305986 Binding of Nfe2l2 and Cul3 1 0.39 0.44 0
47 INT319660 Negative_regulation of Binding of Nfe2l2 and Gadd45gip1 1 0.39 0.11 0
48 INT319659 Sfn Positive_regulation of Nfe2l2 1 0.18 0 0
49 INT317767 Nfe2l2 Regulation of Serpina1a 1 0.21 0 0
50 INT319691 Binding of Gadd45gip1 and Regulation of Nfe2l2 1 0.24 0.23 0
51 INT319656 Gadd45gip1 Regulation of Gene_expression of Nfe2l2 1 0.55 0.89 0
52 INT317766 Nfe2l2 Regulation of Gstm1 1 0.11 0 0
53 INT319664 Gadd45gip1 Positive_regulation of Protein_catabolism of Nfe2l2 1 0.42 0.66 0
54 INT315267 Gopc Negative_regulation of Gene_expression of Nfe2l2 1 0.09 0.48 0
55 INT319689 Binding of Nfe2l2 and Sfn 1 0.14 0.12 0
56 INT249750 Nfe2l2 Regulation of Gene_expression of TFAM 1 0.00 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18024. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18024. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118390 Positive_regulation of Nfe2l2 82 0.70 20.41 10.61
2 INT118388 Localization of Nfe2l2 40 0.81 9.59 5.89
3 INT119544 Gene_expression of Nfe2l2 50 0.77 19.32 4.19
4 INT118393 Positive_regulation of Localization of Nfe2l2 9 0.70 2.82 3.3
5 INT118394 Positive_regulation of Positive_regulation of Nfe2l2 13 0.70 1.4 2.81
6 INT154651 Negative_regulation of Nfe2l2 19 0.59 10.48 2.01
7 INT119540 Binding of Nfe2l2 29 0.48 6.34 1.74
8 INT147471 Positive_regulation of Gene_expression of Nfe2l2 10 0.57 4.18 1.43
9 INT144623 Negative_regulation of Gene_expression of Nfe2l2 10 0.47 3.6 1.17
10 INT147685 Negative_regulation of Binding of Nfe2l2 3 0.35 0.42 0.67
11 INT147686 Negative_regulation of Localization of Nfe2l2 1 0.20 0 0.66
12 INT159065 Phosphorylation of Nfe2l2 1 0.16 0.66 0.66
13 INT131223 Regulation of Nfe2l2 21 0.62 5.57 0.65
14 INT167739 Positive_regulation of Negative_regulation of Nfe2l2 3 0.48 2.08 0.52
15 INT239159 Transcription of Nfe2l2 9 0.58 3.59 0.37
16 INT167743 Negative_regulation of Positive_regulation of Nfe2l2 6 0.47 2.34 0.35
17 INT167738 Regulation of Gene_expression of Nfe2l2 7 0.50 2.31 0.31
18 INT154655 Negative_regulation of Negative_regulation of Nfe2l2 3 0.43 0.72 0.28
19 INT167740 Regulation of Regulation of Nfe2l2 2 0.37 1.01 0.1
20 INT319644 Regulation of Binding of Nfe2l2 1 0.37 0.64 0.09
21 INT305922 Protein_catabolism of Nfe2l2 2 0.81 3.53 0
22 INT315232 Regulation of Negative_regulation of Nfe2l2 1 0.37 0.49 0
23 INT319611 Positive_regulation of Protein_catabolism of Nfe2l2 1 0.41 0.87 0
24 INT319637 Positive_regulation of Binding of Nfe2l2 1 0.41 0.06 0
25 INT319642 Positive_regulation of Transcription of Nfe2l2 1 0.41 0.12 0
26 INT319616 Regulation of Transcription of Nfe2l2 1 0.37 0.12 0
27 INT319617 Positive_regulation of Regulation of Nfe2l2 1 0.41 0 0
28 INT319627 Regulation of Positive_regulation of Nfe2l2 1 0.37 0 0
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