G:18033

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Official Symbol Nfkb1
Aliases p50, p105, NF-KB1, p50/p105, NF-kappaB, NF-kappaB1
EntrezGene 18033
UniProt Coming Soon
Unique Molecular Interactions 133
Total Molecular Interactions 156
Total Single Events 1334
Unique Interaction Partners 91

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Nfkb1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Nfkb1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Nfkb1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
2 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
3 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
4 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
5 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
6 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
7 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
8 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
9 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
10 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
11 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
12 INT152702 Nfkb1 Negative_regulation of Ltp 1 0.01 0.15 0.89
13 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
14 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
15 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
16 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
17 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79
18 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
19 INT159593 Regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.38 0.46 0.74
20 INT135215 Nfkb1 Regulation of Gene_expression of Gmeb1 1 0.01 0.48 0.69
21 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
22 INT135214 Gmeb1 Regulation of Gene_expression of Nfkb1 1 0.01 0.48 0.69
23 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
24 INT135210 Ighen Regulation of Gene_expression of Nfkb1 1 0.01 0.47 0.68
25 INT135212 Nfkb1 Regulation of Gene_expression of Ighen 1 0.01 0.47 0.68
26 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
27 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56
28 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56
29 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55
30 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55
31 INT93951 Nfkb1 Regulation of Gene_expression of Timp1 1 0.00 0.26 0.51
32 INT201740 Positive_regulation of Ngf Positive_regulation of Nfkb1 1 0.01 1.07 0.51
33 INT81661 Binding of Nfkb1 and Pdyn 1 0.00 0 0.5
34 INT143922 TMSB4X Negative_regulation of Positive_regulation of Nfkb1 1 0.01 1.22 0.5
35 INT103934 Cps1 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.2 0.49
36 INT166841 ANXA1 Negative_regulation of Binding of ANXA1 and Nfkb1 1 0.33 0.85 0.48
37 INT201727 Ngf Positive_regulation of Nfkb1 1 0.01 1 0.48
38 INT81662 Pdyn Positive_regulation of Nfkb1 1 0.00 0 0.48
39 INT131819 Binding of Cpox and Nfkb1 1 0.15 0.44 0.46
40 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
41 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44
42 INT157567 Nfkb1 Regulation of Gene_expression of tf 1 0.03 0.74 0.43
43 INT347901 Positive_regulation of Nfkb1 Regulation of Transcription of Gtf3a 1 0.00 0.45 0.42
44 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
45 INT135972 Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.41
46 INT347902 Nfkb1 Regulation of Transcription of Gtf3a 1 0.00 0.45 0.41
47 INT178340 Cxcl1 Positive_regulation of Nfkb1 1 0.11 1.01 0.41
48 INT154756 Tnf Positive_regulation of Nfkb1 1 0.31 0.78 0.4
49 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4
50 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
51 INT152241 Mapk14 Positive_regulation of Localization of Nfkb1 1 0.25 0.13 0.39
52 INT168427 RYBP Positive_regulation of Nfkb1 1 0.01 0.53 0.38
53 INT97404 Nfkb1 Positive_regulation of Transcription of JUN 1 0.00 1.03 0.38
54 INT97403 JUN Positive_regulation of Transcription of Nfkb1 1 0.00 1.03 0.38
55 INT287438 HTS Negative_regulation of Nfkb1 1 0.01 1.77 0.37
56 INT127099 Memo1 Negative_regulation of Nfkb1 1 0.11 0.57 0.36
57 INT127100 Memo1 Negative_regulation of Binding of Nfkb1 1 0.11 0.57 0.36
58 INT110760 Tnfaip8 Positive_regulation of Positive_regulation of Nfkb1 1 0.14 0.87 0.34
59 INT110759 Tnfaip8 Positive_regulation of Nfkb1 1 0.13 0.87 0.34
60 INT165766 Tnfsf11 Negative_regulation of Tnfsf11 Positive_regulation of Nfkb1 1 0.00 1.08 0.33
61 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33
62 INT103391 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of Nfkb1 1 0.01 0.88 0.32
63 INT61266 Nfkb1 Regulation of Gene_expression of Itgam 1 0.23 0.65 0.32
64 INT103390 Negative_regulation of SLC9A1 Negative_regulation of Nfkb1 1 0.01 0.88 0.32
65 INT61265 Nfkb1 Regulation of Gene_expression of Sele 1 0.28 0.65 0.32
66 INT146963 TCF19 Negative_regulation of Nfkb1 1 0.12 1.3 0.31
67 INT267123 ROS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.01 1.05 0.31
68 INT146964 Negative_regulation of TCF19 Negative_regulation of Nfkb1 1 0.12 1.3 0.31
69 INT208947 Pax3 Positive_regulation of Tacr1 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
70 INT143722 Binding of Ikbkg and Nfkb1 1 0.02 0.79 0.29
71 INT71888 Phosphorylation of Nfkb1 Positive_regulation of Nfkb1 1 0.00 0.39 0.29
72 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
73 INT143721 Positive_regulation of Binding of Ikbkg and Nfkb1 1 0.03 0.8 0.29
74 INT168809 Nfkb1 Positive_regulation of Transcription of Trub1 1 0.02 0.44 0.28
75 INT116561 Ptpn5 Positive_regulation of Nfkb1 1 0.04 0.66 0.27
76 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26
77 INT143725 Chuk Negative_regulation of Phosphorylation of Nfkb1 1 0.17 0.71 0.26
78 INT146701 Nfkb1 Regulation of Gene_expression of TNF 1 0.02 0.72 0.26
79 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
80 INT146962 TCF19 Regulation of Nfkb1 1 0.07 1.17 0.24
81 INT146961 TCF19 Regulation of Gene_expression of Nfkb1 1 0.12 1.17 0.24
82 INT142751 Thpo Positive_regulation of Positive_regulation of Nfkb1 1 0.47 1.04 0.24
83 INT316375 Ang Positive_regulation of Nfkb1 1 0.08 0.73 0.23
84 INT154644 Nfkb1 Negative_regulation of Nfkb1 1 0.00 0.17 0.23
85 INT165919 Tlr4 Positive_regulation of Positive_regulation of Nfkb1 1 0.16 0.55 0.23
86 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23
87 INT154757 Negative_regulation of Tnf Positive_regulation of Nfkb1 1 0.19 0.45 0.22
88 INT329530 Malt1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.48 0.22
89 INT231843 Tlr4 Positive_regulation of Nfkb1 1 0.01 1.23 0.22
90 INT344398 Nfkb1 Positive_regulation of Gene_expression of IL6 1 0.12 0.56 0.21
91 INT165636 Ptpn6 Regulation of Nfkb1 1 0.01 0.36 0.2
92 INT168425 Ptger2 Negative_regulation of RYBP Positive_regulation of Nfkb1 1 0.01 0.27 0.19
93 INT154754 Positive_regulation of Tnf Positive_regulation of Nfkb1 1 0.21 0.34 0.18
94 INT150366 Nfkb1 Regulation of Gene_expression of Pomc 1 0.03 0.17 0.17
95 INT172829 Binding of Nfkb1 and ISYNA1 1 0.00 2.06 0.17
96 INT172820 Binding of Nfkb1 and T2dm2 1 0.00 2.14 0.17
97 INT179501 Tlr4 Regulation of Nfkb1 1 0.05 0.3 0.17
98 INT168807 Binding of Nfkb1 and Ptges 1 0.04 0.35 0.16
99 INT172837 ROS1 Positive_regulation of Nfkb1 1 0.00 2.11 0.16
100 INT137510 Nfkb1 Positive_regulation of Gene_expression of ABCB1 1 0.17 0.59 0.14
101 INT226907 Binding of E2f1 and Nfkb1 1 0.14 0.6 0.12
102 INT226904 Nfkb1 Regulation of Gene_expression of Vcam1 1 0.14 0.27 0.12
103 INT167747 Negative_regulation of Nfkb1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.45 0.41 0.11
104 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
105 INT167745 Negative_regulation of Nfkb1 Negative_regulation of Nfe2l2 1 0.45 0.41 0.11
106 INT226910 Slc11a1 Positive_regulation of Localization of Nfkb1 1 0.11 0.62 0.11
107 INT161178 Binding of Nfkb1 and Trpc6 1 0.35 0.74 0.11
108 INT208939 Positive_regulation of Tacr1 Positive_regulation of Nfkb1 1 0.19 0 0.1
109 INT167746 Nfkb1 Positive_regulation of Gene_expression of Nfe2l2 1 0.53 0.45 0.09
110 INT208937 Nfkb1 Positive_regulation of Gene_expression of Nppa 1 0.04 0.38 0.08
111 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
112 INT140048 Mapk7 Positive_regulation of Nfkb1 1 0.53 0.38 0.08
113 INT201736 Nfkb1 Positive_regulation of Transcription of Sod2 1 0.01 0.93 0.08
114 INT138133 Nfkb1 Regulation of Positive_regulation of Mmp13 1 0.00 0.31 0.07
115 INT224453 Nfkb1 Positive_regulation of Gene_expression of VEGFA 1 0.08 0.37 0.07
116 INT138134 Nfkb1 Positive_regulation of Adamts4 1 0.01 0.26 0.06
117 INT174678 Nfkb1 Positive_regulation of Luc7l3 1 0.13 1.13 0.05
118 INT201729 Traf6 Positive_regulation of Phosphorylation of Nfkb1 1 0.00 0.45 0.04
119 INT201739 Traf6 Positive_regulation of Localization of Nfkb1 1 0.00 0.45 0.04
120 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03
121 INT201732 Ngfr Positive_regulation of Nfkb1 1 0.01 0.43 0.03
122 INT95305 RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
123 INT95308 Binding of RELA and Nfkb1 1 0.00 0.08 0
124 INT228217 Nfkb1 Regulation of Gene_expression of Ptger2 1 0.01 1.22 0
125 INT95306 Negative_regulation of RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
126 INT228214 Nfkb1 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.97 0
127 INT225595 Ncoa6 Regulation of Nfkb1 1 0.04 0.21 0
128 INT226896 Slc11a1 Positive_regulation of Binding of Nfkb1 1 0.11 0.08 0
129 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0
130 INT95307 Negative_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
131 INT225528 Ncoa6 Positive_regulation of Nfkb1 1 0.08 0 0
132 INT228218 Negative_regulation of Nfkb1 Negative_regulation of Gene_expression of Ptger2 1 0.01 1.13 0
133 INT95304 Positive_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
134 INT226909 Positive_regulation of Binding of Nfkb1 and Slc11a1 1 0.07 0.18 0
135 INT226898 Binding of Nfkb1 and Slc11a1 1 0.06 0.2 0
136 INT226908 Binding of Nfkb1 and Map3k8 1 0.14 0.14 0
137 INT225546 Gene_expression of Nfkb1 Positive_regulation of Positive_regulation of gr 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18033. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18033. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
2 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
3 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
4 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
5 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
6 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
7 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
8 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
9 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48
10 INT71878 Protein_catabolism of Nfkb1 24 0.65 10.85 9.46
11 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89
12 INT61258 Transcription of Nfkb1 24 0.67 10.89 6.32
13 INT88873 Negative_regulation of Gene_expression of Nfkb1 24 0.56 9.93 5.97
14 INT87211 Positive_regulation of Localization of Nfkb1 27 0.59 15.84 5.25
15 INT66757 Negative_regulation of Binding of Nfkb1 17 0.57 8.14 4.94
16 INT71882 Phosphorylation of Nfkb1 20 0.81 11.46 4.1
17 INT71877 Positive_regulation of Protein_catabolism of Nfkb1 9 0.24 2.73 3.06
18 INT78581 Positive_regulation of Binding of Nfkb1 13 0.66 7.37 2.79
19 INT69009 Regulation of Binding of Nfkb1 9 0.27 9.86 2.58
20 INT95808 Negative_regulation of Negative_regulation of Nfkb1 8 0.41 2.84 2.44
21 INT71881 Positive_regulation of Phosphorylation of Nfkb1 5 0.45 1.38 2.24
22 INT101937 Negative_regulation of Protein_catabolism of Nfkb1 6 0.19 3.21 2.21
23 INT100256 Positive_regulation of Transcription of Nfkb1 8 0.49 3.41 2.2
24 INT61255 Negative_regulation of Transcription of Nfkb1 6 0.23 2.79 2.2
25 INT100940 Regulation of Negative_regulation of Nfkb1 5 0.35 3.59 1.91
26 INT87214 Regulation of Positive_regulation of Nfkb1 7 0.43 5.85 1.79
27 INT143712 Negative_regulation of Phosphorylation of Nfkb1 4 0.39 1.64 1.73
28 INT52530 Regulation of Gene_expression of Nfkb1 8 0.59 4.41 1.68
29 INT117735 Positive_regulation of Regulation of Nfkb1 3 0.44 2.93 0.91
30 INT95286 Regulation of Localization of Nfkb1 6 0.60 3.82 0.71
31 INT137944 Regulation of Transcription of Nfkb1 2 0.45 0.87 0.58
32 INT165914 Positive_regulation of Negative_regulation of Nfkb1 2 0.48 1.01 0.34
33 INT228183 Regulation of Protein_catabolism of Nfkb1 1 0.12 0.24 0.05
34 INT228185 Regulation of Phosphorylation of Nfkb1 1 0.12 0.29 0.04
35 INT228196 Regulation of Regulation of Nfkb1 1 0.12 1.13 0
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