G:18390

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Official Symbol Oprm1
Aliases mor, Oprm, muOR, MOP-R, MOR-1, M-OR-1, MOR-1O
EntrezGene 18390
UniProt Coming Soon
Unique Molecular Interactions 214
Total Molecular Interactions 320
Total Single Events 2270
Unique Interaction Partners 122

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Oprm1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Oprm1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Oprm1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
3 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
6 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
7 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
8 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
9 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
10 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
11 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
12 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
13 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
14 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
15 INT259198 Oprm1 Negative_regulation of Binding of Oprm1 and Flna 1 0.00 0 2.64
16 INT259214 Oprm1 Negative_regulation of Binding of Flna and Flna 1 0.01 0 2.64
17 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
18 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
19 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
20 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
21 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
22 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
23 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
24 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
25 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
26 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
27 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
28 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
29 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
30 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
31 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
32 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
33 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
34 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
35 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
36 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
37 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
38 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
39 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
40 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
41 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
42 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
43 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
44 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
45 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
46 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
47 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
48 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
49 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
50 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
51 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
52 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
53 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
54 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
55 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
56 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
57 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
58 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
59 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
60 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
61 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
62 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
63 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
64 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
65 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
66 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
67 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
68 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
69 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
70 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
71 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
72 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
73 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
74 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
75 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
76 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
77 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
78 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
79 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
80 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
81 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
82 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12
83 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
84 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
85 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
86 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
87 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
88 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
89 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
90 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
91 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
92 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
93 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02
94 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01
95 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
96 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1
97 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
98 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
99 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
100 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
101 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
102 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
103 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
104 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99
105 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
106 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
107 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97
108 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
109 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
110 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
111 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94
112 INT65024 Binding of Oprm1 and Penk 1 0.03 0 0.93
113 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
114 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
115 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
116 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
117 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
118 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
119 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
120 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
121 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
122 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
123 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
124 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
125 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
126 INT6409 Binding of NFKBIL1 and Oprm1 1 0.00 0 0.8
127 INT106838 Lyar Regulation of Oprm1 1 0.04 0.28 0.8
128 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
129 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
130 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
131 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78
132 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
133 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
134 INT140312 Oprm1 Regulation of Gene_expression of Penk 1 0.07 0.26 0.77
135 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
136 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74
137 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
138 INT93710 Oprm1 Positive_regulation of Gene_expression of Calm3 1 0.25 0 0.73
139 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73
140 INT76069 Binding of Oprl1 and Oprm1 1 0.07 0 0.73
141 INT145121 Msh3 Positive_regulation of Oprm1 1 0.06 0.15 0.72
142 INT145120 Msh3 Negative_regulation of Positive_regulation of Oprm1 1 0.05 0.15 0.72
143 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
144 INT107933 Oprm1 Positive_regulation of Gene_expression of Mastl 1 0.33 0.61 0.71
145 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
146 INT138428 Binding of Oprm1 and Pomc Positive_regulation of Gene_expression of Pomc 1 0.30 0.38 0.7
147 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
148 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
149 INT207544 Qsox1 Regulation of Oprm1 1 0.08 0.06 0.7
150 INT340116 Dusp1 Regulation of Transcription of Oprm1 1 0.12 0.71 0.69
151 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68
152 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65
153 INT200357 Binding of Oprm1 and Rest Negative_regulation of Rorb 1 0.00 0 0.64
154 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
155 INT145122 Oprm1 Negative_regulation of Msh3 1 0.06 0.15 0.63
156 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
157 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63
158 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
159 INT124158 Binding of Oprm1 and Rgs7 1 0.30 0.18 0.62
160 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 0.44 0.13 0.62
161 INT124159 Binding of Oprm1 and Rgs11 1 0.31 0.18 0.62
162 INT200334 Binding of Oprm1 and Nenf 1 0.01 0 0.61
163 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6
164 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58
165 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57
166 INT114009 Pomc Regulation of Binding of Crygs and Oprm1 1 0.03 0 0.56
167 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
168 INT114921 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.06 0.05 0.54
169 INT114008 Pomc Positive_regulation of Binding of Crygs and Oprm1 1 0.03 0 0.54
170 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
171 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
172 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
173 INT95059 Binding of Oprm1 and Slc18a3 1 0.04 0 0.52
174 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
175 INT114930 Binding of Oprm1 and Crebbp Positive_regulation of Positive_regulation of Creb1 1 0.06 0 0.51
176 INT114931 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Creb1 1 0.16 0 0.51
177 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5
178 INT200329 Dbp Negative_regulation of Gene_expression of Oprm1 1 0.03 0.07 0.5
179 INT149169 Binding of Oprm1 and Atxn2l 1 0.07 0 0.5
180 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
181 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
182 INT200325 Ahrr Regulation of Oprm1 1 0.00 0.09 0.49
183 INT113752 Binding of PENK and Oprm1 1 0.01 0 0.47
184 INT113750 Negative_regulation of Binding of PENK and Oprm1 1 0.01 0 0.47
185 INT165944 Il13 Positive_regulation of Oprm1 1 0.50 0.46 0.47
186 INT207545 U Regulation of Gene_expression of Oprm1 1 0.00 0.25 0.47
187 INT200345 Binding of Gtf3a and Negative_regulation of Gene_expression of Oprm1 1 0.01 0.05 0.46
188 INT163040 E2f1 Positive_regulation of Transcription of Oprm1 1 0.00 0 0.46
189 INT200336 Gtf3a Negative_regulation of Gene_expression of Oprm1 1 0.01 0 0.45
190 INT106243 Oprm1 Regulation of Gene_expression of IL8 1 0.00 0 0.45
191 INT126829 Oprm1 Positive_regulation of Rtl1 1 0.41 0 0.43
192 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
193 INT200339 Preb Negative_regulation of Gene_expression of Oprm1 1 0.02 0.08 0.4
194 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
195 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
196 INT200303 Oprm1 Negative_regulation of Rorb 1 0.00 0.1 0.39
197 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38
198 INT200355 Binding of Rest and Sp3 Regulation of Oprm1 1 0.22 0.07 0.38
199 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
200 INT241072 Tpr Positive_regulation of Regulation of Oprm1 1 0.01 0.08 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18390. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18390. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
3 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
4 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
5 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
6 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
7 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
8 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
9 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
10 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
11 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
12 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
13 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
14 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
15 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
16 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
17 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
18 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
19 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
20 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96
21 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67
22 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85
23 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71
24 INT62524 Negative_regulation of Phosphorylation of Oprm1 7 0.59 0.08 6.92
25 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9
26 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59
27 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08
28 INT8731 Regulation of Localization of Oprm1 3 0.43 0.25 3.4
29 INT68812 Regulation of Regulation of Oprm1 5 0.40 0.16 3.28
30 INT62522 Regulation of Phosphorylation of Oprm1 3 0.13 0 1.96
31 INT105997 Positive_regulation of Protein_catabolism of Oprm1 2 0.66 0.41 1.45
32 INT129374 Negative_regulation of Regulation of Oprm1 3 0.43 0.58 1.18
33 INT123412 Negative_regulation of Transcription of Oprm1 2 0.56 0.06 0.79
34 INT149198 Positive_regulation of Regulation of Oprm1 2 0.47 0.23 0.42
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