G:18439

Official Symbol P2rx7 Aliases P2X7R, P2X(7), AI467586 EntrezGene 18439 UniProt Coming Soon

Unique Molecular Interactions 29 Total Molecular Interactions 34 Total Single Events 326 Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to P2rx7. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to P2rx7. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to P2rx7. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT151779	Calca Positive_regulation of Transcription of P2rx7	1	0.02	0.54	0.87
2	INT205706	P2rx7 Regulation of Gene_expression of Il18	1	0.21	1.35	0.7
3	INT205702	P2rx7 Regulation of Gene_expression of Il1	1	0.04	1.38	0.67
4	INT205705	Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6	1	0.07	1.42	0.58
5	INT216941	P2rx7 Regulation of Ryr1	1	0.01	0.55	0.52
6	INT205704	P2rx7 Regulation of Localization of Il18	1	0.09	0.67	0.35
7	INT205713	Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8	1	0.03	0.77	0.33
8	INT217025	P2rx7 Regulation of Gene_expression of Ik	1	0.00	0.25	0.33
9	INT217024	Regulation of P2rx7 Regulation of Gene_expression of Ik	1	0.00	0.25	0.33
10	INT205703	P2rx7 Regulation of Positive_regulation of Casp1	1	0.11	0.66	0.33
11	INT205711	P2rx7 Regulation of Localization of IL8	1	0.02	0.92	0.33
12	INT145682	Binding of P2rx4 and P2rx7	2	0.25	0.36	0.31
13	INT205701	P2rx7 Positive_regulation of Il1	1	0.04	0.8	0.25
14	INT216911	Positive_regulation of P2rx7 Positive_regulation of Localization of Plg	1	0.02	0.13	0.23
15	INT216946	P2rx7 Regulation of Il10	1	0.28	0.17	0.21
16	INT205710	CAMP Positive_regulation of P2rx7	1	0.02	0.47	0.19
17	INT270827	P2rx7 Positive_regulation of Localization of Panx1	1	0.41	0.18	0.13
18	INT216945	Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1	1	0.14	0.18	0.12
19	INT205708	Binding of Icam1 and P2rx7	1	0.08	1.03	0.09
20	INT217036	IRF6 Positive_regulation of Gene_expression of P2rx7	1	0.02	0	0.09
21	INT270824	Binding of P2rx7 and Panx1	1	0.34	0.15	0.09
22	INT304464	Binding of P2rx7 and P2rx6	1	0.05	0	0.09
23	INT243156	Positive_regulation of P2rx7 Positive_regulation of NOS1	1	0.00	0.08	0.08
24	INT270829	P2rx7 Positive_regulation of Panx1	1	0.66	0.08	0.08
25	INT270835	Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1	1	0.04	0.08	0.07
26	INT270825	P2rx7 Positive_regulation of Slc37a4	1	0.01	0	0.04
27	INT217031	Binding of P2rx7 and Positive_regulation of Casp1	1	0.02	0	0
28	INT217032	Binding of P2rx7 and Positive_regulation of Il1	1	0.02	0	0
29	INT216942	Positive_regulation of P2rx7 Positive_regulation of Casp1	1	0.14	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18439. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18439. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT88327	Gene_expression of P2rx7	109	0.77	48.86	22.41
2	INT121241	Positive_regulation of P2rx7	65	0.69	40.94	13.59
3	INT88326	Negative_regulation of P2rx7	16	0.58	8.77	6.25
4	INT145680	Regulation of P2rx7	22	0.61	11.92	5.42
5	INT144830	Positive_regulation of Gene_expression of P2rx7	22	0.68	9.78	3.92
6	INT144828	Binding of P2rx7	19	0.47	7.84	3.16
7	INT144829	Localization of P2rx7	12	0.79	2.92	2.12
8	INT216936	Negative_regulation of Gene_expression of P2rx7	5	0.42	2.59	1.84
9	INT125735	Transcription of P2rx7	3	0.62	1.34	1.58
10	INT205691	Regulation of Gene_expression of P2rx7	5	0.44	3.25	1.42
11	INT205690	Positive_regulation of Positive_regulation of P2rx7	14	0.68	6.26	1.3
12	INT151776	Positive_regulation of Transcription of P2rx7	1	0.03	0.53	0.86
13	INT125734	Negative_regulation of Transcription of P2rx7	1	0.38	0.81	0.67
14	INT121239	Regulation of Positive_regulation of P2rx7	2	0.61	1.32	0.32
15	INT216937	Regulation of Binding of P2rx7	1	0.44	0.08	0.29
16	INT216938	Negative_regulation of Localization of P2rx7	1	0.37	0.25	0.24
17	INT216940	Negative_regulation of Binding of P2rx7	1	0.37	0.15	0.2
18	INT216889	Phosphorylation of P2rx7	1	0.23	0	0.18
19	INT270813	Positive_regulation of Localization of P2rx7	1	0.46	0.24	0.15