G:18505

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Official Symbol Pax3
Aliases Sp, Pax-3, splotch
EntrezGene 18505
UniProt Coming Soon
Unique Molecular Interactions 49
Total Molecular Interactions 76
Total Single Events 406
Unique Interaction Partners 35

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pax3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pax3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pax3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
3 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
4 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
5 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
6 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
7 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
8 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
9 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
10 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
11 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
12 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
13 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
14 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
15 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
16 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
17 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
18 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
19 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
20 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
21 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
22 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
23 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
24 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
25 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
26 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
27 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
28 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
29 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
30 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
31 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
32 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
33 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
34 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
35 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
36 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
37 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
38 INT126339 Pax3 Regulation of Insrr 1 0.00 0.56 0.44
39 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
40 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42
41 INT15104 Binding of Pax3 and Penk 1 0.01 0 0.37
42 INT208947 Pax3 Positive_regulation of Tacr1 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
43 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
44 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29
45 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
46 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25
47 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
48 INT294904 Binding of Pax3 and Slc12a3 1 0.02 1.9 0.2
49 INT231622 Pax3 Positive_regulation of Il17a 1 0.03 1.01 0.19
50 INT149115 Cat Negative_regulation of Pax3 1 0.02 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18505. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18505. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8534 Localization of Pax3 85 0.59 28.71 82.82
2 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
3 INT4913 Binding of Pax3 52 0.28 9.57 42.67
4 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
5 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
6 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
7 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
8 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
9 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
10 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
11 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
12 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
13 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
14 INT48807 Regulation of Binding of Pax3 2 0.13 0 2.59
15 INT121224 Positive_regulation of Positive_regulation of Pax3 5 0.14 2.32 2.4
16 INT70558 Regulation of Localization of Pax3 1 0.20 0.07 2.29
17 INT213959 Transcription of Pax3 2 0.03 0.68 1.54
18 INT189015 Negative_regulation of Positive_regulation of Pax3 1 0.12 0.31 1.31
19 INT170442 Positive_regulation of Binding of Pax3 2 0.17 2.05 1.24
20 INT118779 Positive_regulation of Protein_catabolism of Pax3 1 0.47 0.05 1.2
21 INT118783 Negative_regulation of Protein_catabolism of Pax3 1 0.35 0.09 0.89
22 INT15247 Negative_regulation of Negative_regulation of Pax3 1 0.16 0 0.86
23 INT170437 Regulation of Positive_regulation of Pax3 1 0.03 0 0.45
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