G:18619

From wiki-pain
Jump to: navigation, search
Official Symbol Penk
Aliases ENK, PPA, Penk1, AI326464
EntrezGene 18619
UniProt Coming Soon
Unique Molecular Interactions 34
Total Molecular Interactions 48
Total Single Events 539
Unique Interaction Partners 29

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Penk. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Penk. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Penk. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
2 INT75069 Penk Regulation of Gene_expression of Pkhd1l1 1 0.09 0 1.85
3 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
4 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
5 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87
6 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
7 INT140312 Oprm1 Regulation of Gene_expression of Penk 1 0.07 0.26 0.77
8 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 0.10 0 0.66
9 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
10 INT82383 Penk Positive_regulation of Gene_expression of Il1f5 1 0.04 0 0.65
11 INT82385 Penk Positive_regulation of Gene_expression of Il1 1 0.07 0 0.65
12 INT103000 Cpe Regulation of Penk 1 0.07 0.19 0.62
13 INT11280 Fos Regulation of Transcription of Penk 1 0.04 0.55 0.57
14 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
15 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
16 INT68252 Penk Positive_regulation of Transcription of Ighg1 1 0.44 0 0.44
17 INT68253 Penk Positive_regulation of Transcription of IgG2a 1 0.29 0 0.44
18 INT87369 Il4 Positive_regulation of Penk 1 0.37 0 0.28
19 INT115413 Binding of Penk and Oxtr 1 0.00 0 0.25
20 INT67084 Penk Positive_regulation of Gene_expression of Ifng 1 0.06 0.08 0.23
21 INT67085 Penk Positive_regulation of Positive_regulation of Il4 1 0.06 0.08 0.23
22 INT131718 Mapk8 Regulation of Penk 1 0.46 0.16 0.2
23 INT57383 Binding of Creb1 and Penk 1 0.05 0.67 0.2
24 INT72513 LOC100044193 Regulation of Regulation of Penk 1 0.00 0.56 0.17
25 INT65414 Penk Positive_regulation of Binding of Sst 1 0.19 0.38 0.1
26 INT165159 Gli1 Regulation of Penk 1 0.24 0.07 0.09
27 INT65409 Penk Positive_regulation of Sst 1 0.19 0.19 0.05
28 INT65410 Penk Positive_regulation of Uchl1 1 0.05 0.19 0.05
29 INT80067 Penk Positive_regulation of Gene_expression of Glb1 1 0.07 0.1 0.05
30 INT65415 Penk Positive_regulation of Binding of Uchl1 1 0.05 0.19 0.05
31 INT57382 Creb1 Regulation of Gene_expression of Penk 1 0.06 0.51 0
32 INT93172 Ttf1 Negative_regulation of Transcription of Penk 1 0.01 0.07 0
33 INT114539 Binding of Pcsk2 and Penk 1 0.07 0 0
34 INT114540 Binding of Pcsk1 and Penk 1 0.06 0 0
35 INT63733 Fos Positive_regulation of Gene_expression of Penk 1 0.53 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18619. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18619. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13
2 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29
3 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05
4 INT21344 Negative_regulation of Penk 34 0.57 8.83 23.32
5 INT9780 Regulation of Penk 30 0.60 6.78 17.19
6 INT8530 Transcription of Penk 48 0.70 11.67 16.34
7 INT5854 Regulation of Gene_expression of Penk 22 0.61 6.91 10.03
8 INT11276 Localization of Penk 10 0.00 2.94 6.63
9 INT40178 Binding of Penk 11 0.44 0.23 6.21
10 INT8529 Regulation of Transcription of Penk 8 0.39 1.26 5.89
11 INT19641 Negative_regulation of Gene_expression of Penk 11 0.58 1.12 4.91
12 INT15618 Positive_regulation of Transcription of Penk 12 0.58 3.21 3.8
13 INT90932 Negative_regulation of Positive_regulation of Penk 3 0.41 0.36 2.66
14 INT148191 Positive_regulation of Localization of Penk 2 0.61 1.22 2.48
15 INT57282 Positive_regulation of Negative_regulation of Penk 4 0.49 0.84 2.26
16 INT90933 Positive_regulation of Protein_catabolism of Penk 1 0.28 0 1.44
17 INT90934 Negative_regulation of Protein_catabolism of Penk 1 0.24 0 1.44
18 INT70015 Protein_catabolism of Penk 3 0.64 0 1.11
19 INT11274 Positive_regulation of Positive_regulation of Penk 3 0.48 0.47 1.08
20 INT40176 Negative_regulation of Binding of Penk 2 0.54 0 1.08
21 INT75064 Negative_regulation of Transcription of Penk 1 0.51 0 0.97
22 INT326658 Regulation of Localization of Penk 1 0.24 0.75 0.96
23 INT218029 Positive_regulation of Binding of Penk 1 0.18 0 0.79
24 INT49612 Regulation of Regulation of Penk 2 0.25 0.62 0.44
25 INT57381 Positive_regulation of Regulation of Penk 1 0.05 0.66 0.2
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox