G:18708

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Official Symbol Pik3r1
Aliases PI3K, AA414921, p50alpha, p55alpha, p85alpha, C530050K14
EntrezGene 18708
UniProt Coming Soon
Unique Molecular Interactions 53
Total Molecular Interactions 67
Total Single Events 355
Unique Interaction Partners 36

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pik3r1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pik3r1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pik3r1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
2 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
3 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
4 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
5 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
6 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
7 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
8 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
9 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
10 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
11 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
12 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
13 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
14 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
15 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
16 INT168781 Tnf Positive_regulation of Binding of Pik3r1 and Tnf 1 0.00 0.73 0.33
17 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
18 INT185141 Pik3r1 Positive_regulation of Snrpd1 1 0.00 0.16 0.29
19 INT166163 Binding of Ccr9 and Ccl25 Positive_regulation of Pik3r1 1 0.44 1.47 0.28
20 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
21 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18
22 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
23 INT253488 Ptger2 Positive_regulation of Ptger4 Positive_regulation of Positive_regulation of Pik3r1 1 0.06 1.2 0.13
24 INT166153 Pik3r1 Regulation of Gene_expression of Ccr9 1 0.36 0.78 0.12
25 INT317888 Binding of Eef1a1 and Pik3r1 1 0.01 1.04 0.11
26 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
27 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
28 INT213051 Hdl1 Positive_regulation of Pik3r1 1 0.13 1.93 0.09
29 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08
30 INT331796 Akt1 Negative_regulation of Negative_regulation of Pik3r1 1 0.04 0.88 0.08
31 INT340553 Pik3r1 Regulation of Gene_expression of Fbxo32 1 0.04 0.52 0.07
32 INT340320 Binding of Shc1 and Positive_regulation of Pik3r1 1 0.23 0 0.07
33 INT120569 Binding of Egfr and Pik3r1 1 0.40 1.22 0.06
34 INT120570 Positive_regulation of Binding of Egfr and Pik3r1 1 0.55 1.22 0.06
35 INT213016 Regulation of Hdl1 Positive_regulation of Pik3r1 1 0.09 0.97 0.05
36 INT199106 Negative_regulation of Pik3r1 Negative_regulation of Gene_expression of Ros1 1 0.03 0.08 0.04
37 INT213031 Positive_regulation of Pik3r1 Positive_regulation of Gene_expression of Nos3 1 0.10 0.8 0.04
38 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03
39 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
40 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
41 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
42 INT306646 Mapk1 Regulation of Pik3r1 1 0.03 0.39 0
43 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
44 INT176551 Binding of Pik3r1 and Spp1 1 0.03 0.65 0
45 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0
46 INT253565 Akt1 Positive_regulation of Positive_regulation of Pik3r1 1 0.10 0 0
47 INT211572 Binding of Kit and Pik3r1 1 0.21 0.06 0
48 INT176553 Pik3r1 Positive_regulation of Positive_regulation of Mapk14 1 0.02 0.41 0
49 INT176542 Pik3r1 Positive_regulation of Positive_regulation of Mapk1 1 0.01 0.41 0
50 INT176536 Binding of Pik3r1 and Mtv7 1 0.02 0.46 0
51 INT253581 Pik3r1 Regulation of Binding of Csnk2a2 and Sp3 1 0.06 0.06 0
52 INT211574 Regulation of Binding of Kit and Pik3r1 1 0.16 0.06 0
53 INT306618 Myoz1 Regulation of Pik3r1 1 0.00 0.39 0
54 INT176550 Pik3r1 Positive_regulation of Gene_expression of Spp1 1 0.05 0.47 0
55 INT253567 Binding of Pik3r1 and Sp3 1 0.11 0.06 0
56 INT176557 Binding of Pik3r1 and Mtv7 Regulation of Gene_expression of Spp1 1 0.02 0.46 0
57 INT211571 Pik3r1 Positive_regulation of Gene_expression of Kit 1 0.30 0.3 0
58 INT278380 Syk Positive_regulation of Pik3r1 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18708. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18708. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
2 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
3 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
4 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
5 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
6 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
7 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
8 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
9 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
10 INT109301 Positive_regulation of Phosphorylation of Pik3r1 5 0.42 1.45 1.38
11 INT288191 Positive_regulation of Localization of Pik3r1 4 0.15 1.27 0.81
12 INT166456 Negative_regulation of Gene_expression of Pik3r1 4 0.41 1.72 0.64
13 INT135666 Negative_regulation of Negative_regulation of Pik3r1 2 0.29 0.3 0.6
14 INT168766 Positive_regulation of Binding of Pik3r1 3 0.21 1.54 0.35
15 INT212985 Negative_regulation of Positive_regulation of Pik3r1 3 0.19 3.28 0.3
16 INT185119 Regulation of Positive_regulation of Pik3r1 3 0.13 0.45 0.3
17 INT236698 Transcription of Pik3r1 1 0.15 1.3 0.18
18 INT309653 Negative_regulation of Localization of Pik3r1 1 0.14 0.55 0.15
19 INT288190 Regulation of Localization of Pik3r1 1 0.04 0.07 0.1
20 INT308619 Regulation of Phosphorylation of Pik3r1 1 0.09 1.06 0.06
21 INT239161 Positive_regulation of Negative_regulation of Pik3r1 1 0.30 0.77 0
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