G:18787

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Official Symbol Serpine1
Aliases PAI1, PAI-1, Planh1
EntrezGene 18787
UniProt Coming Soon
Unique Molecular Interactions 26
Total Molecular Interactions 35
Total Single Events 337
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Serpine1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Serpine1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Serpine1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130355 spc Regulation of Serpine1 1 0.14 0.2 0.66
2 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
3 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
4 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
5 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 0.03 1.3 0.23
6 INT255257 Binding of Serpine1 and Tsp1 1 0.07 0.85 0.2
7 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
8 INT294207 Serpine1 Regulation of Gene_expression of Plat 1 0.50 0.92 0.16
9 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
10 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12
11 INT158615 Binding of Serpine1 and Plaur 1 0.04 0.38 0.1
12 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09
13 INT230746 Crp Positive_regulation of Localization of Serpine1 1 0.16 0.27 0.09
14 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08
15 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
16 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05
17 INT213037 Hdl1 Positive_regulation of Gene_expression of Serpine1 1 0.19 1.19 0.04
18 INT254867 Ctgf Negative_regulation of Serpine1 1 0.04 0.51 0.03
19 INT120661 Positive_regulation of Plg Positive_regulation of Serpine1 1 0.00 0 0
20 INT294205 Serpine1 Negative_regulation of Plat 1 0.47 0.51 0
21 INT294204 Binding of Serpine1 and Plat 1 0.46 0.2 0
22 INT251893 Serpine1 Negative_regulation of Plau 1 0.39 0.6 0
23 INT251891 Serpine1 Negative_regulation of Plg 1 0.12 3.13 0
24 INT115465 Binding of Serpine1 and Plau 1 0.00 0.05 0
25 INT120660 Plg Positive_regulation of Serpine1 1 0.00 0 0
26 INT57791 Binding of Serpine1 and Plat 1 0.00 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18787. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18787. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
2 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
3 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
4 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6
5 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97
6 INT23188 Localization of Serpine1 22 0.79 16.06 1.96
7 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29
8 INT54137 Positive_regulation of Positive_regulation of Serpine1 4 0.70 0.79 1.06
9 INT112336 Binding of Serpine1 8 0.41 4.62 0.78
10 INT20101 Regulation of Positive_regulation of Serpine1 1 0.10 0.94 0.44
11 INT126530 Negative_regulation of Positive_regulation of Serpine1 3 0.43 2.62 0.38
12 INT200606 Regulation of Gene_expression of Serpine1 4 0.38 2.07 0.35
13 INT172783 Regulation of Localization of Serpine1 3 0.30 3.83 0.32
14 INT99739 Protein_catabolism of Serpine1 4 0.87 1.71 0.29
15 INT125772 Positive_regulation of Negative_regulation of Serpine1 1 0.42 0.4 0.22
16 INT125773 Transcription of Serpine1 4 0.53 2.35 0.19
17 INT212989 Negative_regulation of Localization of Serpine1 1 0.26 2.2 0.16
18 INT212957 Positive_regulation of Localization of Serpine1 2 0.50 1.89 0.15
19 INT254810 Negative_regulation of Protein_catabolism of Serpine1 1 0.08 0.51 0.03
20 INT254787 Positive_regulation of Protein_catabolism of Serpine1 1 0.10 0.52 0.03
21 INT254802 Phosphorylation of Serpine1 1 0.05 0 0
22 INT200607 Positive_regulation of Regulation of Serpine1 1 0.42 0.97 0
23 INT310172 Positive_regulation of Transcription of Serpine1 1 0.18 1.99 0
24 INT310178 Negative_regulation of Transcription of Serpine1 1 0.15 0.98 0
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