G:19013

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Official Symbol Ppara
Aliases Ppar, Nr1c1, AW742785, PPARalpha, PPAR-alpha, 4933429D07Rik
EntrezGene 19013
UniProt Coming Soon
Unique Molecular Interactions 110
Total Molecular Interactions 141
Total Single Events 2516
Unique Interaction Partners 82

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Ppara. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Ppara. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Ppara. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
2 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
3 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
4 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 0.18 0.79 0.4
5 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4
6 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
7 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
8 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38
9 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
10 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38
11 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
12 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37
13 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
14 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
15 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
16 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
17 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28
18 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
19 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
20 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
21 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
22 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23
23 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23
24 INT229702 Binding of Ppara and Ros1 1 0.01 1.05 0.23
25 INT263339 Ptger2 Regulation of Ppara 1 0.09 0.44 0.21
26 INT220513 Ugt1a6b Positive_regulation of Ppara 1 0.01 0.98 0.18
27 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
28 INT220524 Ppara Negative_regulation of Positive_regulation of Gdf15 1 0.01 0.56 0.17
29 INT220516 Ppara Negative_regulation of Positive_regulation of Atf3 1 0.10 0.56 0.17
30 INT290670 Binding of Nos2 and Ppara 1 0.17 0.41 0.16
31 INT332968 Hoxb4 Positive_regulation of Ppara 1 0.02 0.25 0.16
32 INT225608 Ppara Regulation of Ncoa6 1 0.27 0.44 0.14
33 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14
34 INT215394 Binding of Csf2 and Positive_regulation of Ppara 1 0.12 0.49 0.14
35 INT332966 Binding of Fas and Ppara 1 0.15 0.25 0.13
36 INT145058 Nr1i3 Regulation of Transcription of Ppara 1 0.28 0.23 0.13
37 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13
38 INT332893 Ppara Regulation of Gene_expression of Arntl 1 0.43 0 0.11
39 INT342227 TRNAI1 Positive_regulation of Ppara 1 0.03 1.06 0.11
40 INT202619 Binding of Ppara and Spna1 1 0.01 0.27 0.1
41 INT332891 Per2 Positive_regulation of Ppara 1 0.43 0 0.1
42 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09
43 INT290673 Ppara Positive_regulation of Gtf3a 1 0.01 0.58 0.09
44 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09
45 INT290674 Ppara Positive_regulation of Gtf3a Positive_regulation of Ppara 1 0.01 0.58 0.09
46 INT234437 asa Negative_regulation of Ppara 1 0.13 0.4 0.09
47 INT229703 Binding of Ppara and Rxrg 1 0.03 0.08 0.08
48 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
49 INT336383 TIMP1 Positive_regulation of Ppara 1 0.08 0.77 0.07
50 INT236936 Ppara Positive_regulation of Mapk1 1 0.09 0.64 0.07
51 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
52 INT332897 Ppara Regulation of Transcription of Clock 1 0.24 0.31 0.06
53 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
54 INT332880 Arntl Regulation of Ppara 1 0.29 0 0.06
55 INT250635 Ppara Positive_regulation of SLC16A13 1 0.22 0 0.05
56 INT256548 Regulation of Cd320 Positive_regulation of Ppara 1 0.28 0.43 0.05
57 INT332900 Ppara Regulation of Clock 1 0.21 0 0.05
58 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
59 INT329218 Phosphorylation of Ppara Positive_regulation of Prkag1 1 0.34 0.2 0.05
60 INT256551 Cd320 Regulation of Cd320 Positive_regulation of Ppara 1 0.31 0.43 0.05
61 INT145060 Binding of PPARA and Ppara 1 0.10 0.26 0.05
62 INT145057 Binding of Ppara and Plcl1 1 0.36 0.26 0.05
63 INT239334 Ppara Negative_regulation of Gene_expression of Apo 1 0.06 1.18 0.05
64 INT342225 Gene_expression of TRNAI1 Negative_regulation of Gene_expression of Ppara 1 0.03 0.19 0.05
65 INT332895 Binding of Ppara and Ncor1 1 0.31 0.15 0.05
66 INT233855 Binding of Ppara and Mapk7 1 0.09 0.9 0.05
67 INT256547 Cd320 Positive_regulation of Ppara 1 0.47 0.43 0.05
68 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
69 INT236725 Binding of Ppara and KLK15 1 0.02 0.08 0.04
70 INT332888 Binding of Arntl and Ppara 1 0.34 0 0.04
71 INT263337 Ptger4 Regulation of Ppara 1 0.02 0.3 0.04
72 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04
73 INT235434 SSB Positive_regulation of Ppara 1 0.00 1.56 0.04
74 INT342356 Arrd1 Positive_regulation of Negative_regulation of Ppara 1 0.01 0.81 0.04
75 INT332889 Clock Regulation of Ppara 1 0.12 0 0.04
76 INT332886 Binding of Clock and Ppara 1 0.32 0 0.04
77 INT236149 Binding of Ncoa1 and Ppara 1 0.07 0 0.03
78 INT236146 Binding of Ppara and Pprc1 1 0.01 0 0.03
79 INT239330 Positive_regulation of Ppara Positive_regulation of Hdl1 1 0.05 1.17 0.03
80 INT332970 Binding of Ppara and Tmed4 1 0.05 1.91 0.03
81 INT194485 SNRNP70 Regulation of Ppara 1 0.00 0.53 0
82 INT332958 Binding of Esr1 and Ppara 1 0.36 0.21 0
83 INT263336 Ppara Regulation of Olfm4 1 0.00 0.33 0
84 INT332887 Clock Positive_regulation of Ppara 1 0.71 0 0
85 INT332960 Atp6v1e1 Negative_regulation of Ppara 1 0.18 0.99 0
86 INT332965 Binding of Atp6v1e1 and Ppara 1 0.15 0.36 0
87 INT301635 Ppara Positive_regulation of Gene_expression of Fabp1 1 0.26 0.29 0
88 INT301657 Binding of Dbi and Ppara 1 0.26 0.23 0
89 INT332969 Binding of Atp6v1e1 and Positive_regulation of Ppara 1 0.21 0 0
90 INT332884 Clock Regulation of Gene_expression of Ppara 1 0.63 0.06 0
91 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0
92 INT256543 Fabp4 Positive_regulation of Ppara 1 0.29 0 0
93 INT301621 Ppara Positive_regulation of Gene_expression of Mttp 1 0.22 0.59 0
94 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0
95 INT301669 PPA1 Positive_regulation of Ppara 1 0.02 0.14 0
96 INT342223 Binding of TRNAI1 and Ppara 1 0.03 0.18 0
97 INT285389 Binding of Ppara and Mgst1 1 0.11 0.22 0
98 INT263338 Ptger2 Positive_regulation of Ppara 1 0.17 0 0
99 INT342224 Negative_regulation of Binding of TRNAI1 and Ppara 1 0.03 0.18 0
100 INT235431 cla Positive_regulation of Ppara 1 0.06 0.6 0
101 INT332885 Binding of Ppara and Ppargc1a 1 0.40 0.3 0
102 INT236723 VEGFA Positive_regulation of Positive_regulation of Ppara 1 0.12 1.01 0
103 INT256546 Fabp5 Positive_regulation of Ppara 1 0.24 0 0
104 INT332973 Atp6v1e1 Positive_regulation of Ppara 1 0.19 0 0
105 INT332899 Binding of Ppara and Tcf12 1 0.02 0 0
106 INT181835 Binding of Baat and Ppara 1 0.09 0.31 0
107 INT332959 Atp6v1e1 Negative_regulation of Gene_expression of Ppara 1 0.18 1.33 0
108 INT307210 Ide Positive_regulation of Ppara 1 0.02 0.18 0
109 INT307216 Ppara Regulation of Srebf1 1 0.22 0.12 0
110 INT307208 Binding of Ppara and Nrip1 1 0.34 0.31 0
111 INT332967 Atp6v1e1 Regulation of Ppara 1 0.11 0.47 0
112 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0
113 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 19013. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 19013. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
2 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
3 INT122041 Binding of Ppara 308 0.48 189.17 51.48
4 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
5 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
6 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
7 INT194462 Localization of Ppara 94 0.78 68.33 12.09
8 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
9 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
10 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
11 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
12 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
13 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
14 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
15 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
16 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
17 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
18 INT122040 Positive_regulation of Transcription of Ppara 9 0.50 3.97 1.33
19 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21
20 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2
21 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17
22 INT227552 Regulation of Phosphorylation of Ppara 7 0.44 3.13 0.92
23 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91
24 INT236707 Regulation of Negative_regulation of Ppara 5 0.41 2.97 0.8
25 INT180458 Regulation of Regulation of Ppara 6 0.45 6.44 0.49
26 INT197168 Regulation of Localization of Ppara 6 0.39 3.7 0.41
27 INT194468 Positive_regulation of Phosphorylation of Ppara 4 0.46 2.11 0.38
28 INT239779 Negative_regulation of Regulation of Ppara 4 0.42 1.48 0.36
29 INT215377 Negative_regulation of Protein_catabolism of Ppara 2 0.31 0.5 0.35
30 INT145051 Regulation of Transcription of Ppara 5 0.43 2.14 0.31
31 INT301573 Positive_regulation of Protein_catabolism of Ppara 1 0.37 0.28 0.22
32 INT178770 Negative_regulation of Negative_regulation of Ppara 2 0.32 1.24 0.09
33 INT203727 Negative_regulation of Phosphorylation of Ppara 4 0.42 3.54 0.07
34 INT233882 Negative_regulation of Transcription of Ppara 3 0.58 1.76 0
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