G:1909

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Official Symbol EDNRA
Aliases ETA, ET-A, ETAR, ETRA, ETA-R, hET-AR
EntrezGene 1909
UniProt Coming Soon
Unique Molecular Interactions 40
Total Molecular Interactions 63
Total Single Events 292
Unique Interaction Partners 26

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to EDNRA. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to EDNRA. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to EDNRA. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
2 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
3 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
4 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
5 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
6 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
7 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
8 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
9 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
10 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53
11 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
12 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
13 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
14 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
15 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
16 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 0.03 1.1 0.35
17 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
18 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
19 INT69365 Binding of EDNRA and Pnoc 1 0.00 0 0.31
20 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
21 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
22 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
23 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
24 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26
25 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24
26 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
27 INT36876 EDNRA Regulation of Negative_regulation of PRB1 1 0.00 0 0.21
28 INT178059 Binding of EDN1 and EDNRA Positive_regulation of Phosphorylation of PXN 1 0.04 0.83 0.2
29 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
30 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 0.02 0.55 0.18
31 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
32 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 0.06 0.55 0.18
33 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
34 INT219920 EDNRA Positive_regulation of Trpv1 1 0.14 0 0.13
35 INT293627 GHRL Positive_regulation of EDNRA 1 0.00 0.96 0.1
36 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09
37 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
38 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
39 INT337297 PTAFR Positive_regulation of EDNRA 1 0.04 1.2 0.06
40 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 0.10 0.88 0.06
41 INT337303 Positive_regulation of PTAFR Positive_regulation of EDNRA 1 0.04 1.21 0.06
42 INT339778 Binding of EDNRA and PTH 1 0.12 0.35 0.05
43 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04
44 INT107859 PRSS1 Positive_regulation of EDNRA 1 0.03 0.69 0.04
45 INT115611 Binding of EDNRA and ERBB2 1 0.08 0.78 0
46 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1909. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1909. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
2 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
3 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
4 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
5 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
6 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
7 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
8 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
9 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88
10 INT186686 Regulation of Positive_regulation of EDNRA 5 0.22 2.35 0.51
11 INT120405 Phosphorylation of EDNRA 1 0.61 0.38 0.48
12 INT158057 Positive_regulation of Positive_regulation of EDNRA 2 0.15 0 0.41
13 INT350970 Negative_regulation of Binding of EDNRA 1 0.41 0.86 0.29
14 INT72023 Positive_regulation of Localization of EDNRA 1 0.02 0.07 0.18
15 INT72025 Negative_regulation of Localization of EDNRA 1 0.01 0.07 0.18
16 INT173335 Negative_regulation of Gene_expression of EDNRA 2 0.19 0.71 0.17
17 INT70908 Transcription of EDNRA 1 0.08 0.33 0.12
18 INT70906 Negative_regulation of Transcription of EDNRA 1 0.05 0.33 0.12
19 INT283233 Regulation of Regulation of EDNRA 1 0.04 2.22 0.05
20 INT246353 Protein_catabolism of EDNRA 1 0.01 0.48 0.04
21 INT186688 Regulation of Binding of EDNRA 1 0.03 0.36 0
22 INT186687 Negative_regulation of Regulation of EDNRA 1 0.03 0.28 0
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