G:19122

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Official Symbol Prnp
Aliases PrP, PrPC, Sinc, CD230, PrPSc, Prn-i, Prn-p, PrP<C>, AA960666, AI325101, prP27-30, prP33-35C
EntrezGene 19122
UniProt Coming Soon
Unique Molecular Interactions 43
Total Molecular Interactions 58
Total Single Events 1184
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Prnp. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Prnp. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Prnp. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41
2 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4
3 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
4 INT231305 Positive_regulation of Binding of Prnp and Helt 1 0.03 1.63 0.19
5 INT134698 Regulation of Prnp Positive_regulation of Nup214 1 0.26 1.18 0.14
6 INT134697 Prnp Positive_regulation of Nup214 1 0.44 1.18 0.13
7 INT231301 Prnp Regulation of Regulation of Grin1 1 0.26 0.24 0.08
8 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08
9 INT229539 Cpz Negative_regulation of Localization of Prnp 1 0.05 0.58 0.07
10 INT229538 Cpz Negative_regulation of Positive_regulation of Prnp 1 0.05 0.58 0.07
11 INT231300 Positive_regulation of Grin2b Positive_regulation of Prnp 1 0.39 0.16 0.05
12 INT231299 Prnp Regulation of Grin2d 1 0.28 0 0.05
13 INT231302 Binding of Grin2d and Prnp 1 0.38 0.11 0.05
14 INT231311 Prnp Negative_regulation of Helt 1 0.04 0.05 0.03
15 INT231308 Prnp Negative_regulation of Gene_expression of Grin1 1 0.41 0.05 0.03
16 INT231312 Prnp Negative_regulation of Grin1 1 0.42 0.05 0.03
17 INT260518 Binding of Prnp and Gopc 2 0.13 1.06 0
18 INT268647 ATP2B3 Positive_regulation of Prnp 1 0.01 0.57 0
19 INT335952 Prnp Positive_regulation of can 1 0.17 0.58 0
20 INT268183 Gene_expression of Rab22a Negative_regulation of Gene_expression of Prnp 1 0.28 0.1 0
21 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
22 INT260523 Binding of Cnp and Prnp 1 0.33 0.34 0
23 INT268192 Gene_expression of Rab22a Positive_regulation of Protein_catabolism of Prnp 1 0.30 0.08 0
24 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0
25 INT268648 ATP2B3 Regulation of ATP2B3 Positive_regulation of Prnp 1 0.00 0.57 0
26 INT268191 Rab4a Regulation of Gene_expression of Prnp 1 0.23 0.22 0
27 INT231314 Prnp Positive_regulation of Grin2d Regulation of Prnp 1 0.32 0.16 0
28 INT260522 Binding of Myc and Prnp 1 0.30 0.35 0
29 INT335950 Negative_regulation of Prnp Positive_regulation of can 1 0.16 0.59 0
30 INT268197 Gene_expression of Rab22a Regulation of Prnp 1 0.29 0.08 0
31 INT268184 Prnp Regulation of Gene_expression of Rab22a 1 0.34 0.17 0
32 INT231313 Prnp Positive_regulation of Grin2d 1 0.47 0.16 0
33 INT268201 Tg(CAG-EGFP)D4Nagy Regulation of Prnp 1 0.01 0.22 0
34 INT268198 Prnp Positive_regulation of Erc1 1 0.04 0.26 0
35 INT268194 Erc1 Positive_regulation of Gene_expression of Prnp 1 0.05 0.2 0
36 INT268190 Gene_expression of Rab22a Negative_regulation of Prnp 1 0.32 0.08 0
37 INT268177 Rab4a Regulation of Prnp 1 0.14 0.22 0
38 INT268182 Positive_regulation of Binding of Prnp and Erc1 1 0.06 0.1 0
39 INT268188 Binding of Prnp and Erc1 1 0.04 0.27 0
40 INT268185 Rab22a Negative_regulation of Gene_expression of Prnp 1 0.32 0.08 0
41 INT268195 Rab22a Negative_regulation of Prnp 1 0.44 0.09 0
42 INT268176 Positive_regulation of Erc1 Positive_regulation of Gene_expression of Prnp 1 0.06 0.2 0
43 INT287034 Pgp Regulation of Positive_regulation of Prnp 1 0.13 0.09 0
44 INT268646 Prnp Positive_regulation of PRNP 1 0.08 0.42 0
45 INT354482 Binding of PRNP and Prnp 1 0.16 0.88 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 19122. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 19122. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
2 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
3 INT69572 Localization of Prnp 96 0.81 38.11 5.45
4 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81
5 INT69570 Binding of Prnp 75 0.48 44.26 4.37
6 INT102255 Regulation of Prnp 35 0.62 18.97 3.25
7 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62
8 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45
9 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03
10 INT136634 Transcription of Prnp 9 0.72 3.34 0.83
11 INT190662 Regulation of Positive_regulation of Prnp 4 0.24 1.15 0.7
12 INT69571 Positive_regulation of Positive_regulation of Prnp 6 0.70 5.88 0.67
13 INT124164 Protein_catabolism of Prnp 20 1.00 8.58 0.44
14 INT229518 Phosphorylation of Prnp 5 0.69 1.62 0.27
15 INT331055 Positive_regulation of Phosphorylation of Prnp 1 0.07 0.24 0.27
16 INT69568 Positive_regulation of Localization of Prnp 5 0.50 2.43 0.26
17 INT268171 Negative_regulation of Binding of Prnp 3 0.42 0.82 0.25
18 INT190664 Regulation of Binding of Prnp 3 0.52 4.29 0.1
19 INT207304 Positive_regulation of Protein_catabolism of Prnp 9 0.69 2.08 0.09
20 INT207302 Positive_regulation of Transcription of Prnp 1 0.47 0.71 0.06
21 INT229516 Negative_regulation of Positive_regulation of Prnp 5 0.42 0.95 0.04
22 INT229519 Regulation of Localization of Prnp 4 0.61 0.7 0.03
23 INT287031 Positive_regulation of Negative_regulation of Prnp 1 0.46 0.16 0.03
24 INT268144 Negative_regulation of Localization of Prnp 3 0.37 0.71 0
25 INT190666 Positive_regulation of Binding of Prnp 2 0.50 1.87 0
26 INT268161 Regulation of Negative_regulation of Prnp 2 0.39 0.33 0
27 INT229517 Regulation of Phosphorylation of Prnp 1 0.39 0.26 0
28 INT315417 Negative_regulation of Transcription of Prnp 1 0.43 0.14 0
29 INT268173 Negative_regulation of Negative_regulation of Prnp 1 0.37 0 0
30 INT268148 Regulation of Protein_catabolism of Prnp 1 0.45 0 0
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