G:19164

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Official Symbol Psen1
Aliases PS1, Ad3h, PS-1, S182
EntrezGene 19164
UniProt Coming Soon
Unique Molecular Interactions 22
Total Molecular Interactions 32
Total Single Events 407
Unique Interaction Partners 16

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Psen1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Psen1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Psen1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
2 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
3 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
4 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
5 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
6 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
7 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
8 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
9 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
10 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
11 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
12 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
13 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
14 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
15 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
16 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
17 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
18 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
19 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
20 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
21 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
22 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 19164. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 19164. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
2 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
3 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
4 INT163544 Binding of Psen1 40 0.36 15.28 2.42
5 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
6 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
7 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
8 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
9 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
10 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
11 INT193856 Localization of Psen1 19 0.73 9.79 0.41
12 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
13 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
14 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
15 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
16 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
17 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
18 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
19 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
20 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
21 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
22 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
23 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
24 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
25 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
26 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
27 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
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