G:19225

From wiki-pain
Jump to: navigation, search
Official Symbol Ptgs2
Aliases COX2, Cox-2, PHS-2, Pghs2, TIS10, PGHS-2
EntrezGene 19225
UniProt Coming Soon
Unique Molecular Interactions 24
Total Molecular Interactions 31
Total Single Events 518
Unique Interaction Partners 21

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Ptgs2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Ptgs2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Ptgs2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
3 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
4 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
5 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
6 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
7 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
8 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
9 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
10 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26
11 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
12 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
13 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21
14 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
15 INT283747 Tbs1 Positive_regulation of Ptgs2 1 0.00 0 0.2
16 INT119130 Binding of Nos2 and Ptgs2 1 0.33 0.07 0.17
17 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16
18 INT117568 Dspp Negative_regulation of Ptgs2 1 0.11 0.13 0.12
19 INT87922 Gm7869 Negative_regulation of Ptgs2 1 0.01 0.56 0.1
20 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1
21 INT327559 Pla2g4a Positive_regulation of Gene_expression of Ptgs2 1 0.14 1 0.09
22 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
23 INT149883 Agtr2 Positive_regulation of Gene_expression of Ptgs2 1 0.06 0.31 0
24 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 19225. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 19225. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
2 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
3 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
4 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
5 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
6 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
7 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
8 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
9 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
10 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
11 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
12 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
13 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
14 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
15 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
16 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
17 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
18 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
19 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
20 INT87715 Negative_regulation of Negative_regulation of Ptgs2 1 0.16 0.68 0.17
21 INT247598 Regulation of Binding of Ptgs2 1 0.10 1.69 0.16
22 INT52697 Regulation of Positive_regulation of Ptgs2 2 0.27 0.34 0.13
23 INT212801 Phosphorylation of Ptgs2 2 0.22 1.03 0.1
24 INT283729 Protein_catabolism of Ptgs2 1 0.01 0.09 0.08
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox