G:1950

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Official Symbol EGF
Aliases URG, HOMG4
EntrezGene 1950
UniProt Coming Soon
Unique Molecular Interactions 91
Total Molecular Interactions 131
Total Single Events 471
Unique Interaction Partners 53

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to EGF. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to EGF. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to EGF. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
2 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
3 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
4 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
5 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
6 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
7 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
8 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
9 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
10 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
11 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
12 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
13 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
14 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
15 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
16 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
17 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
18 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
19 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
20 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
21 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
22 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
23 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52
24 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
25 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
26 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
27 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
28 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
29 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
30 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
31 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
32 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
33 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32
34 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32
35 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27
36 INT285243 EGF Positive_regulation of Egf 1 0.00 1.55 0.27
37 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
38 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
39 INT220750 EGF Positive_regulation of PCa 1 0.05 0.45 0.23
40 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
41 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
42 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22
43 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
44 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21
45 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
46 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
47 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
48 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19
49 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
50 INT186098 EGF Positive_regulation of MAP2K5 1 0.01 0.19 0.18
51 INT24668 Binding of COL7A1 and EGF 1 0.14 0.25 0.16
52 INT238329 EGF Regulation of Negative_regulation of ADAMTS5 1 0.03 0 0.14
53 INT238338 Binding of EGF and Regulation of Gene_expression of GOPC 1 0.05 0 0.14
54 INT238337 EGF Regulation of Gene_expression of GOPC 1 0.03 0 0.14
55 INT238342 Binding of EGF and Regulation of Gene_expression of ADAMTS1 1 0.05 0 0.14
56 INT73924 EGF Positive_regulation of Localization of COL7A1 1 0.31 0.33 0.13
57 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
58 INT287266 EGF Positive_regulation of EGF Positive_regulation of CDC42 1 0.06 0.16 0.11
59 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
60 INT156829 EGF Positive_regulation of MAPK3 2 0.08 0.87 0.1
61 INT286963 EGF Positive_regulation of Gene_expression of STAT3 1 0.03 0.57 0.1
62 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08
63 INT309903 Binding of EGF and TXK 1 0.03 0.23 0.08
64 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07
65 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07
66 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
67 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
68 INT24666 Binding of EGF and FGF2 1 0.35 0 0.06
69 INT27738 CBS Positive_regulation of EGF 1 0.33 0.85 0.05
70 INT27737 CBS Positive_regulation of Positive_regulation of EGF 1 0.36 0.85 0.05
71 INT186097 EGF Positive_regulation of Positive_regulation of EGFR 1 0.20 0.38 0.04
72 INT285071 EGF Positive_regulation of CCL16 1 0.03 0.77 0
73 INT274060 EGF Positive_regulation of EGFR Positive_regulation of TKT 1 0.08 1 0
74 INT293801 EGF Positive_regulation of EPHB2 1 0.11 0 0
75 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0
76 INT327101 Binding of AREG and EGF 1 0.05 0.35 0
77 INT227670 EGF Positive_regulation of Gene_expression of ISYNA1 1 0.01 2.92 0
78 INT277664 Negative_regulation of Binding of EGF and EGFR 1 0.18 0.5 0
79 INT160861 Erbb2 Regulation of EGF 1 0.49 0.73 0
80 INT177945 EGF Regulation of ras 1 0.02 0.84 0
81 INT177915 EGF Positive_regulation of Phosphorylation of AKT1 1 0.03 0.51 0
82 INT274061 EGF Positive_regulation of EGFR Positive_regulation of TXK 1 0.06 1 0
83 INT309906 Binding of EGF and SRC 1 0.11 0.64 0
84 INT327100 Binding of BTC and EGF 1 0.04 0.35 0
85 INT177917 Positive_regulation of EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0
86 INT210494 Binding of EGF and TEP1 1 0.02 0.19 0
87 INT277897 EGF Positive_regulation of CALCRL 1 0.00 0.77 0
88 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0
89 INT180851 EGF Positive_regulation of Transcription of MT1L 1 0.27 1.06 0
90 INT327099 Binding of EGF and EREG 1 0.05 0.35 0
91 INT277896 EGF Positive_regulation of TKT 1 0.02 0.76 0
92 INT274062 EGF Positive_regulation of EGFR Positive_regulation of Positive_regulation of TXK 1 0.06 1 0
93 INT177912 EGF Regulation of MAPK3 1 0.02 0.84 0
94 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0
95 INT177913 EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1950. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1950. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
2 INT11157 Binding of EGF 88 0.48 53.73 21.25
3 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
4 INT2036 Localization of EGF 42 0.77 21.5 9.74
5 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
6 INT37227 Regulation of EGF 19 0.45 11.16 5.17
7 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
8 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
9 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
10 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
11 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
12 INT86382 Negative_regulation of Localization of EGF 5 0.43 1.75 1.44
13 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16
14 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06
15 INT105860 Positive_regulation of Positive_regulation of EGF 6 0.64 2.37 1.05
16 INT118290 Regulation of Phosphorylation of EGF 1 0.32 0.72 0.87
17 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7
18 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56
19 INT13818 Negative_regulation of Protein_catabolism of EGF 1 0.59 0.37 0.27
20 INT111291 Transcription of EGF 2 0.52 0.35 0.17
21 INT111294 Negative_regulation of Transcription of EGF 1 0.32 0.09 0.12
22 INT70651 Positive_regulation of Binding of EGF 1 0.50 0.98 0.09
23 INT118289 Negative_regulation of Phosphorylation of EGF 3 0.40 0.47 0
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