G:19645

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Official Symbol Rb1
Aliases Rb, pRb, Rb-1
EntrezGene 19645
UniProt Coming Soon
Unique Molecular Interactions 21
Total Molecular Interactions 37
Total Single Events 158
Unique Interaction Partners 13

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Rb1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Rb1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Rb1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
2 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
3 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
4 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
5 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
6 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
7 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
8 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
9 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
10 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
11 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
12 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
13 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
14 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0
15 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
16 INT196965 Hmga2 Positive_regulation of Binding of Hmga2 and Rb1 1 0.53 0.36 0
17 INT196950 Binding of Rb1 and E2f2 1 0.01 0.6 0
18 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
19 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
20 INT196945 Rb1 Negative_regulation of Transcription of E2f1 1 0.42 0.35 0
21 INT196963 Binding of E2f1 and Rb1 Negative_regulation of E2f1 1 0.46 0.6 0
22 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
23 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0
24 INT196964 Binding of E2f1 and Rb1 Negative_regulation of Transcription of E2f1 1 0.46 0.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 19645. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 19645. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
2 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
3 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
4 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
5 INT169931 Localization of Rb1 6 0.70 4.79 0.65
6 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
7 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
8 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
9 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
10 INT169930 Binding of Rb1 15 0.43 5.91 0.16
11 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
12 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
13 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03
14 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03
15 INT298776 Regulation of Phosphorylation of Rb1 1 0.04 0.39 0.03
16 INT196935 Negative_regulation of Binding of Rb1 1 0.38 0.24 0
17 INT196910 Positive_regulation of Binding of Rb1 1 0.45 0.81 0
18 INT204055 Positive_regulation of Negative_regulation of Rb1 1 0.03 0.55 0
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