G:20201

From wiki-pain
Jump to: navigation, search
Official Symbol S100a8
Aliases p8, B8Ag, CFAg, Caga, MRP8, CP-10, 60B8Ag, AI323541
EntrezGene 20201
UniProt Coming Soon
Unique Molecular Interactions 38
Total Molecular Interactions 46
Total Single Events 562
Unique Interaction Partners 31

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to S100a8. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to S100a8. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to S100a8. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT161512 Ppig Negative_regulation of Positive_regulation of S100a8 1 0.02 0.23 1.12
2 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
3 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
4 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
5 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
6 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
7 INT190525 Acot1 Positive_regulation of Localization of S100a8 1 0.00 0.86 0.63
8 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62
9 INT164150 Binding of S100a8 and Trpv1 1 0.04 0.6 0.62
10 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
11 INT295270 S100a8 Regulation of Il6 1 0.01 0.56 0.48
12 INT347903 Gtf3a Regulation of Gene_expression of S100a8 1 0.00 0.52 0.44
13 INT337047 Art2b Positive_regulation of Gene_expression of S100a8 1 0.00 1.03 0.42
14 INT230501 Il1 Positive_regulation of Gene_expression of S100a8 1 0.01 1.82 0.39
15 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32
16 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31
17 INT327379 S100a8 Regulation of Oxt 1 0.00 0.95 0.29
18 INT349506 S100a8 Positive_regulation of Gene_expression of Nos2 1 0.02 0.67 0.28
19 INT295266 S100a8 Regulation of Cxcl10 1 0.01 0.28 0.24
20 INT295269 S100a8 Regulation of Irf7 1 0.01 0.28 0.24
21 INT336738 S100a8 Regulation of Gene_expression of Ambp 1 0.02 2.15 0.24
22 INT327315 S100a8 Negative_regulation of Binding of Khsrp 1 0.01 0.55 0.21
23 INT336739 Binding of S100a8 and Tlr4 1 0.19 1.28 0.2
24 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19
25 INT295268 S100a8 Positive_regulation of Stat3 1 0.00 0.5 0.18
26 INT280813 Binding of Avp and S100a8 1 0.00 0.28 0.15
27 INT347336 Binding of S100a4 and S100a8 1 0.40 0.51 0.15
28 INT347332 Binding of S100a8 and Vegfa 1 0.38 0.46 0.15
29 INT347331 Binding of Fgf1 and S100a8 1 0.26 0.46 0.15
30 INT347330 Binding of S100a8 and Il1 1 0.09 0.45 0.15
31 INT347337 Binding of Il6 and S100a8 1 0.29 0.46 0.15
32 INT327329 S100a8 Positive_regulation of Mapk14 1 0.00 0.36 0.14
33 INT324812 Tlr4 Positive_regulation of Gene_expression of S100a8 1 0.11 0.38 0.13
34 INT336740 Positive_regulation of Ambp Positive_regulation of Gene_expression of S100a8 1 0.02 1.3 0.12
35 INT327384 S100a8 Regulation of Gene_expression of Oxtr 1 0.00 0.1 0.1
36 INT278378 Hps5 Positive_regulation of Gene_expression of S100a8 1 0.00 0.42 0.09
37 INT266387 Binding of S100a1 and S100a8 1 0.09 0.17 0.05
38 INT266379 S100a8 Positive_regulation of Ager 1 0.01 0.3 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 20201. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 20201. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02
2 INT97596 Localization of S100a8 94 0.78 90.69 40.41
3 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4
4 INT152729 Negative_regulation of Gene_expression of S100a8 33 0.42 32.25 13.64
5 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99
6 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25
7 INT97598 Negative_regulation of Localization of S100a8 8 0.42 6.52 4.31
8 INT117465 Positive_regulation of Localization of S100a8 8 0.42 10.04 3.89
9 INT125013 Regulation of S100a8 9 0.26 7.93 3.21
10 INT181018 Binding of S100a8 20 0.45 22.14 3.18
11 INT161506 Regulation of Gene_expression of S100a8 6 0.45 4.68 2.9
12 INT204763 Transcription of S100a8 8 0.69 6.22 1.69
13 INT131228 Regulation of Localization of S100a8 4 0.45 1.81 1.65
14 INT152728 Negative_regulation of Positive_regulation of S100a8 4 0.43 3.96 1.29
15 INT275512 Positive_regulation of Negative_regulation of S100a8 1 0.45 2.31 0.63
16 INT241735 Positive_regulation of Positive_regulation of S100a8 1 0.02 0.98 0.59
17 INT236090 Regulation of Negative_regulation of S100a8 1 0.02 1.55 0.54
18 INT323607 Positive_regulation of Regulation of S100a8 1 0.02 1 0.49
19 INT181044 Positive_regulation of Binding of S100a8 1 0.47 1.36 0.28
20 INT204764 Positive_regulation of Transcription of S100a8 1 0.02 1.15 0.22
21 INT206526 Negative_regulation of Transcription of S100a8 1 0.42 0.55 0.18
22 INT125014 Negative_regulation of Phosphorylation of S100a8 1 0.42 0 0
23 INT125016 Phosphorylation of S100a8 1 0.80 0 0
24 INT125012 Regulation of Phosphorylation of S100a8 1 0.26 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox